Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 301 |
Chain | Residue |
A | LEU60 |
A | PRO60 |
A | MET235 |
A | HOH427 |
A | HOH447 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 302 |
Chain | Residue |
A | GLY69 |
A | THR115 |
A | GLN118 |
A | HOH439 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 303 |
Chain | Residue |
A | GLU26 |
A | TRP137 |
A | LYS157 |
A | HOH494 |
site_id | AC4 |
Number of Residues | 9 |
Details | binding site for residue SO4 A 304 |
Chain | Residue |
A | TRP24 |
A | GLY25 |
A | TRP27 |
A | GLY69 |
A | ILE70 |
A | LEU71 |
A | PHE117 |
A | LEU155 |
A | HOH431 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 305 |
Chain | Residue |
A | LEU37 |
A | THR38 |
A | ALA38 |
A | ARG39 |
A | LYS119 |
A | LYS185 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 306 |
Chain | Residue |
A | TRP24 |
A | PHE117 |
A | ASN159 |
A | PRO161 |
A | TYR184 |
A | HOH549 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 307 |
Chain | Residue |
A | GLN34 |
A | GLN38 |
A | LEU73 |
A | ILE76 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 308 |
Chain | Residue |
A | TYR184 |
A | GLY186 |
A | LYS186 |
A | HOH532 |
site_id | AC9 |
Number of Residues | 9 |
Details | binding site for residue MRZ B 100 |
Chain | Residue |
A | ASP189 |
A | ALA190 |
A | THR213 |
A | TRP215 |
A | GLY219 |
A | GLY226 |
A | HOH499 |
B | PHE5 |
B | ALA6 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
Chain | Residue | Details |
A | ASN21 | |
A | ASN113 | |
Chain | Residue | Details |
A | ASN72 | |