5F4Z
The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004301 | molecular_function | epoxide hydrolase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016803 | molecular_function | ether hydrolase activity |
| A | 0097176 | biological_process | epoxide metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004301 | molecular_function | epoxide hydrolase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016803 | molecular_function | ether hydrolase activity |
| B | 0097176 | biological_process | epoxide metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004301 | molecular_function | epoxide hydrolase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016803 | molecular_function | ether hydrolase activity |
| C | 0097176 | biological_process | epoxide metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004301 | molecular_function | epoxide hydrolase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016803 | molecular_function | ether hydrolase activity |
| D | 0097176 | biological_process | epoxide metabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004301 | molecular_function | epoxide hydrolase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016803 | molecular_function | ether hydrolase activity |
| E | 0097176 | biological_process | epoxide metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | HIS82 |
| A | ARG84 |
| A | LEU164 |
| A | GLY165 |
| A | TYR166 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ARG168 |
| A | PRO92 |
| A | GLY165 |
| A | TYR166 |
| A | SER167 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | LEU293 |
| A | HOH523 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ALA58 |
| A | ALA59 |
| A | ARG62 |
| A | HOH511 |
| A | HOH512 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | HIS191 |
| A | HOH505 |
| A | HOH714 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | ASP21 |
| A | ARG51 |
| A | ASP52 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 407 |
| Chain | Residue |
| A | ASP12 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue 5V4 A 408 |
| Chain | Residue |
| A | ASP175 |
| A | TRP179 |
| A | PHE199 |
| A | ILE201 |
| A | PHE228 |
| A | TYR235 |
| A | MSE236 |
| A | TRP268 |
| A | PRO312 |
| A | SER337 |
| A | ALA338 |
| A | HIS363 |
| A | HOH504 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 401 |
| Chain | Residue |
| B | GLU267 |
| B | TRS403 |
| D | HOH505 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue PG4 B 402 |
| Chain | Residue |
| A | HOH568 |
| B | ILE8 |
| B | PRO9 |
| B | ASP12 |
| B | LEU293 |
| B | HOH673 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue TRS B 403 |
| Chain | Residue |
| B | MSE266 |
| B | GLU267 |
| B | TRP268 |
| B | GLY269 |
| B | ALA335 |
| B | ACT401 |
| D | GLU216 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue 5V4 B 404 |
| Chain | Residue |
| B | ASP175 |
| B | TRP179 |
| B | PHE199 |
| B | ILE201 |
| B | PHE228 |
| B | TYR235 |
| B | MSE236 |
| B | TRP268 |
| B | PRO312 |
| B | SER337 |
| B | ALA338 |
| B | HIS363 |
| B | HOH502 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 401 |
| Chain | Residue |
| C | LEU20 |
| C | ASP21 |
| C | TRP25 |
| C | HOH512 |
| C | HOH531 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue 5V4 C 402 |
| Chain | Residue |
| C | ASP175 |
| C | TRP179 |
| C | PHE199 |
| C | ILE201 |
| C | PHE228 |
| C | TYR235 |
| C | MSE236 |
| C | TRP268 |
| C | PRO312 |
| C | SER337 |
| C | ALA338 |
| C | HIS363 |
| C | HOH514 |
| site_id | AD6 |
| Number of Residues | 13 |
| Details | binding site for residue 5V4 D 401 |
| Chain | Residue |
| D | ASP175 |
| D | TRP179 |
| D | PHE199 |
| D | ILE201 |
| D | PHE228 |
| D | TYR235 |
| D | MSE236 |
| D | TRP268 |
| D | PRO312 |
| D | SER337 |
| D | ALA338 |
| D | HIS363 |
| D | HOH508 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 401 |
| Chain | Residue |
| E | TYR166 |
| E | SER167 |
| E | ARG168 |
| E | PRO92 |
| E | GLY165 |
| site_id | AD8 |
| Number of Residues | 12 |
| Details | binding site for residue 5V4 E 402 |
| Chain | Residue |
| E | ASP175 |
| E | TRP179 |
| E | PHE199 |
| E | ILE201 |
| E | PHE228 |
| E | TYR235 |
| E | MSE236 |
| E | TRP268 |
| E | PRO312 |
| E | SER337 |
| E | HIS363 |
| E | HOH502 |
