5F1I

MHC with 9-mer peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002376	biological_process	immune system process
A	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
A	0016020	cellular_component	membrane
A	0030670	cellular_component	phagocytic vesicle membrane
A	0042612	cellular_component	MHC class I protein complex
A	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
B	0000139	cellular_component	Golgi membrane
B	0001913	biological_process	T cell mediated cytotoxicity
B	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
B	0002237	biological_process	response to molecule of bacterial origin
B	0002376	biological_process	immune system process
B	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
B	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
B	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
B	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
B	0002726	biological_process	positive regulation of T cell cytokine production
B	0005198	molecular_function	structural molecule activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005765	cellular_component	lysosomal membrane
B	0005783	cellular_component	endoplasmic reticulum
B	0005788	cellular_component	endoplasmic reticulum lumen
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005925	cellular_component	focal adhesion
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006955	biological_process	immune response
B	0007608	biological_process	sensory perception of smell
B	0007611	biological_process	learning or memory
B	0009897	cellular_component	external side of plasma membrane
B	0009986	cellular_component	cell surface
B	0010038	biological_process	response to metal ion
B	0010977	biological_process	negative regulation of neuron projection development
B	0012507	cellular_component	ER to Golgi transport vesicle membrane
B	0016020	cellular_component	membrane
B	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
B	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
B	0023026	molecular_function	MHC class II protein complex binding
B	0030670	cellular_component	phagocytic vesicle membrane
B	0031901	cellular_component	early endosome membrane
B	0031902	cellular_component	late endosome membrane
B	0031905	cellular_component	early endosome lumen
B	0033077	biological_process	T cell differentiation in thymus
B	0033572	biological_process	transferrin transport
B	0034756	biological_process	regulation of iron ion transport
B	0034757	biological_process	negative regulation of iron ion transport
B	0035580	cellular_component	specific granule lumen
B	0042026	biological_process	protein refolding
B	0042605	molecular_function	peptide antigen binding
B	0042612	cellular_component	MHC class I protein complex
B	0042613	cellular_component	MHC class II protein complex
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0042824	cellular_component	MHC class I peptide loading complex
B	0045646	biological_process	regulation of erythrocyte differentiation
B	0048260	biological_process	positive regulation of receptor-mediated endocytosis
B	0048261	biological_process	negative regulation of receptor-mediated endocytosis
B	0050680	biological_process	negative regulation of epithelial cell proliferation
B	0050768	biological_process	negative regulation of neurogenesis
B	0050778	biological_process	positive regulation of immune response
B	0050870	biological_process	positive regulation of T cell activation
B	0051289	biological_process	protein homotetramerization
B	0055038	cellular_component	recycling endosome membrane
B	0060586	biological_process	multicellular organismal-level iron ion homeostasis
B	0070062	cellular_component	extracellular exosome
B	0071281	biological_process	cellular response to iron ion
B	0071283	biological_process	cellular response to iron(III) ion
B	0071316	biological_process	cellular response to nicotine
B	1904724	cellular_component	tertiary granule lumen
B	1990000	biological_process	amyloid fibril formation
B	1990712	cellular_component	HFE-transferrin receptor complex
B	2000774	biological_process	positive regulation of cellular senescence
B	2000978	biological_process	negative regulation of forebrain neuron differentiation
D	0002376	biological_process	immune system process
D	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
D	0016020	cellular_component	membrane
D	0030670	cellular_component	phagocytic vesicle membrane
D	0042612	cellular_component	MHC class I protein complex
D	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
E	0000139	cellular_component	Golgi membrane
E	0001913	biological_process	T cell mediated cytotoxicity
E	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
E	0002237	biological_process	response to molecule of bacterial origin
E	0002376	biological_process	immune system process
E	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
E	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
E	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
E	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
E	0002726	biological_process	positive regulation of T cell cytokine production
E	0005198	molecular_function	structural molecule activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005765	cellular_component	lysosomal membrane
E	0005783	cellular_component	endoplasmic reticulum
E	0005788	cellular_component	endoplasmic reticulum lumen
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005925	cellular_component	focal adhesion
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006955	biological_process	immune response
E	0007608	biological_process	sensory perception of smell
E	0007611	biological_process	learning or memory
E	0009897	cellular_component	external side of plasma membrane
E	0009986	cellular_component	cell surface
E	0010038	biological_process	response to metal ion
E	0010977	biological_process	negative regulation of neuron projection development
E	0012507	cellular_component	ER to Golgi transport vesicle membrane
E	0016020	cellular_component	membrane
E	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
E	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
E	0023026	molecular_function	MHC class II protein complex binding
E	0030670	cellular_component	phagocytic vesicle membrane
E	0031901	cellular_component	early endosome membrane
E	0031902	cellular_component	late endosome membrane
E	0031905	cellular_component	early endosome lumen
E	0033077	biological_process	T cell differentiation in thymus
E	0033572	biological_process	transferrin transport
E	0034756	biological_process	regulation of iron ion transport
E	0034757	biological_process	negative regulation of iron ion transport
E	0035580	cellular_component	specific granule lumen
E	0042026	biological_process	protein refolding
E	0042605	molecular_function	peptide antigen binding
E	0042612	cellular_component	MHC class I protein complex
E	0042613	cellular_component	MHC class II protein complex
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0042824	cellular_component	MHC class I peptide loading complex
E	0045646	biological_process	regulation of erythrocyte differentiation
E	0048260	biological_process	positive regulation of receptor-mediated endocytosis
E	0048261	biological_process	negative regulation of receptor-mediated endocytosis
E	0050680	biological_process	negative regulation of epithelial cell proliferation
E	0050768	biological_process	negative regulation of neurogenesis
E	0050778	biological_process	positive regulation of immune response
E	0050870	biological_process	positive regulation of T cell activation
E	0051289	biological_process	protein homotetramerization
E	0055038	cellular_component	recycling endosome membrane
E	0060586	biological_process	multicellular organismal-level iron ion homeostasis
E	0070062	cellular_component	extracellular exosome
E	0071281	biological_process	cellular response to iron ion
E	0071283	biological_process	cellular response to iron(III) ion
E	0071316	biological_process	cellular response to nicotine
E	1904724	cellular_component	tertiary granule lumen
E	1990000	biological_process	amyloid fibril formation
E	1990712	cellular_component	HFE-transferrin receptor complex
E	2000774	biological_process	positive regulation of cellular senescence
E	2000978	biological_process	negative regulation of forebrain neuron differentiation
G	0002376	biological_process	immune system process
G	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
G	0016020	cellular_component	membrane
G	0030670	cellular_component	phagocytic vesicle membrane
G	0042612	cellular_component	MHC class I protein complex
G	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
H	0000139	cellular_component	Golgi membrane
H	0001913	biological_process	T cell mediated cytotoxicity
H	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
H	0002237	biological_process	response to molecule of bacterial origin
H	0002376	biological_process	immune system process
H	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
H	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
H	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
H	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
H	0002726	biological_process	positive regulation of T cell cytokine production
H	0005198	molecular_function	structural molecule activity
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0005765	cellular_component	lysosomal membrane
H	0005783	cellular_component	endoplasmic reticulum
H	0005788	cellular_component	endoplasmic reticulum lumen
H	0005794	cellular_component	Golgi apparatus
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0005925	cellular_component	focal adhesion
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006955	biological_process	immune response
H	0007608	biological_process	sensory perception of smell
H	0007611	biological_process	learning or memory
H	0009897	cellular_component	external side of plasma membrane
H	0009986	cellular_component	cell surface
H	0010038	biological_process	response to metal ion
H	0010977	biological_process	negative regulation of neuron projection development
H	0012507	cellular_component	ER to Golgi transport vesicle membrane
H	0016020	cellular_component	membrane
H	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
H	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
H	0023026	molecular_function	MHC class II protein complex binding
H	0030670	cellular_component	phagocytic vesicle membrane
H	0031901	cellular_component	early endosome membrane
H	0031902	cellular_component	late endosome membrane
H	0031905	cellular_component	early endosome lumen
H	0033077	biological_process	T cell differentiation in thymus
H	0033572	biological_process	transferrin transport
H	0034756	biological_process	regulation of iron ion transport
H	0034757	biological_process	negative regulation of iron ion transport
H	0035580	cellular_component	specific granule lumen
H	0042026	biological_process	protein refolding
H	0042605	molecular_function	peptide antigen binding
H	0042612	cellular_component	MHC class I protein complex
H	0042613	cellular_component	MHC class II protein complex
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0042824	cellular_component	MHC class I peptide loading complex
H	0045646	biological_process	regulation of erythrocyte differentiation
H	0048260	biological_process	positive regulation of receptor-mediated endocytosis
H	0048261	biological_process	negative regulation of receptor-mediated endocytosis
H	0050680	biological_process	negative regulation of epithelial cell proliferation
H	0050768	biological_process	negative regulation of neurogenesis
H	0050778	biological_process	positive regulation of immune response
H	0050870	biological_process	positive regulation of T cell activation
H	0051289	biological_process	protein homotetramerization
H	0055038	cellular_component	recycling endosome membrane
H	0060586	biological_process	multicellular organismal-level iron ion homeostasis
H	0070062	cellular_component	extracellular exosome
H	0071281	biological_process	cellular response to iron ion
H	0071283	biological_process	cellular response to iron(III) ion
H	0071316	biological_process	cellular response to nicotine
H	1904724	cellular_component	tertiary granule lumen
H	1990000	biological_process	amyloid fibril formation
H	1990712	cellular_component	HFE-transferrin receptor complex
H	2000774	biological_process	positive regulation of cellular senescence
H	2000978	biological_process	negative regulation of forebrain neuron differentiation
J	0002376	biological_process	immune system process
J	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
J	0016020	cellular_component	membrane
J	0030670	cellular_component	phagocytic vesicle membrane
J	0042612	cellular_component	MHC class I protein complex
J	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
K	0000139	cellular_component	Golgi membrane
K	0001913	biological_process	T cell mediated cytotoxicity
K	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
K	0002237	biological_process	response to molecule of bacterial origin
K	0002376	biological_process	immune system process
K	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
K	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
K	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
K	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
K	0002726	biological_process	positive regulation of T cell cytokine production
K	0005198	molecular_function	structural molecule activity
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0005765	cellular_component	lysosomal membrane
K	0005783	cellular_component	endoplasmic reticulum
K	0005788	cellular_component	endoplasmic reticulum lumen
K	0005794	cellular_component	Golgi apparatus
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0005925	cellular_component	focal adhesion
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006955	biological_process	immune response
K	0007608	biological_process	sensory perception of smell
K	0007611	biological_process	learning or memory
K	0009897	cellular_component	external side of plasma membrane
K	0009986	cellular_component	cell surface
K	0010038	biological_process	response to metal ion
K	0010977	biological_process	negative regulation of neuron projection development
K	0012507	cellular_component	ER to Golgi transport vesicle membrane
K	0016020	cellular_component	membrane
K	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
K	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
K	0023026	molecular_function	MHC class II protein complex binding
K	0030670	cellular_component	phagocytic vesicle membrane
K	0031901	cellular_component	early endosome membrane
K	0031902	cellular_component	late endosome membrane
K	0031905	cellular_component	early endosome lumen
K	0033077	biological_process	T cell differentiation in thymus
K	0033572	biological_process	transferrin transport
K	0034756	biological_process	regulation of iron ion transport
K	0034757	biological_process	negative regulation of iron ion transport
K	0035580	cellular_component	specific granule lumen
K	0042026	biological_process	protein refolding
K	0042605	molecular_function	peptide antigen binding
K	0042612	cellular_component	MHC class I protein complex
K	0042613	cellular_component	MHC class II protein complex
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0042824	cellular_component	MHC class I peptide loading complex
K	0045646	biological_process	regulation of erythrocyte differentiation
K	0048260	biological_process	positive regulation of receptor-mediated endocytosis
K	0048261	biological_process	negative regulation of receptor-mediated endocytosis
K	0050680	biological_process	negative regulation of epithelial cell proliferation
K	0050768	biological_process	negative regulation of neurogenesis
K	0050778	biological_process	positive regulation of immune response
K	0050870	biological_process	positive regulation of T cell activation
K	0051289	biological_process	protein homotetramerization
K	0055038	cellular_component	recycling endosome membrane
K	0060586	biological_process	multicellular organismal-level iron ion homeostasis
K	0070062	cellular_component	extracellular exosome
K	0071281	biological_process	cellular response to iron ion
K	0071283	biological_process	cellular response to iron(III) ion
K	0071316	biological_process	cellular response to nicotine
K	1904724	cellular_component	tertiary granule lumen
K	1990000	biological_process	amyloid fibril formation
K	1990712	cellular_component	HFE-transferrin receptor complex
K	2000774	biological_process	positive regulation of cellular senescence
K	2000978	biological_process	negative regulation of forebrain neuron differentiation
M	0002376	biological_process	immune system process
M	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
M	0016020	cellular_component	membrane
M	0030670	cellular_component	phagocytic vesicle membrane
M	0042612	cellular_component	MHC class I protein complex
M	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
N	0000139	cellular_component	Golgi membrane
N	0001913	biological_process	T cell mediated cytotoxicity
N	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
N	0002237	biological_process	response to molecule of bacterial origin
N	0002376	biological_process	immune system process
N	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
N	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
N	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
N	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
N	0002726	biological_process	positive regulation of T cell cytokine production
N	0005198	molecular_function	structural molecule activity
N	0005515	molecular_function	protein binding
N	0005576	cellular_component	extracellular region
N	0005615	cellular_component	extracellular space
N	0005765	cellular_component	lysosomal membrane
N	0005783	cellular_component	endoplasmic reticulum
N	0005788	cellular_component	endoplasmic reticulum lumen
N	0005794	cellular_component	Golgi apparatus
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0005925	cellular_component	focal adhesion
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0006955	biological_process	immune response
N	0007608	biological_process	sensory perception of smell
N	0007611	biological_process	learning or memory
N	0009897	cellular_component	external side of plasma membrane
N	0009986	cellular_component	cell surface
N	0010038	biological_process	response to metal ion
N	0010977	biological_process	negative regulation of neuron projection development
N	0012507	cellular_component	ER to Golgi transport vesicle membrane
N	0016020	cellular_component	membrane
N	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
N	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
N	0023026	molecular_function	MHC class II protein complex binding
N	0030670	cellular_component	phagocytic vesicle membrane
N	0031901	cellular_component	early endosome membrane
N	0031902	cellular_component	late endosome membrane
N	0031905	cellular_component	early endosome lumen
N	0033077	biological_process	T cell differentiation in thymus
N	0033572	biological_process	transferrin transport
N	0034756	biological_process	regulation of iron ion transport
N	0034757	biological_process	negative regulation of iron ion transport
N	0035580	cellular_component	specific granule lumen
N	0042026	biological_process	protein refolding
N	0042605	molecular_function	peptide antigen binding
N	0042612	cellular_component	MHC class I protein complex
N	0042613	cellular_component	MHC class II protein complex
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0042824	cellular_component	MHC class I peptide loading complex
N	0045646	biological_process	regulation of erythrocyte differentiation
N	0048260	biological_process	positive regulation of receptor-mediated endocytosis
N	0048261	biological_process	negative regulation of receptor-mediated endocytosis
N	0050680	biological_process	negative regulation of epithelial cell proliferation
N	0050768	biological_process	negative regulation of neurogenesis
N	0050778	biological_process	positive regulation of immune response
N	0050870	biological_process	positive regulation of T cell activation
N	0051289	biological_process	protein homotetramerization
N	0055038	cellular_component	recycling endosome membrane
N	0060586	biological_process	multicellular organismal-level iron ion homeostasis
N	0070062	cellular_component	extracellular exosome
N	0071281	biological_process	cellular response to iron ion
N	0071283	biological_process	cellular response to iron(III) ion
N	0071316	biological_process	cellular response to nicotine
N	1904724	cellular_component	tertiary granule lumen
N	1990000	biological_process	amyloid fibril formation
N	1990712	cellular_component	HFE-transferrin receptor complex
N	2000774	biological_process	positive regulation of cellular senescence
N	2000978	biological_process	negative regulation of forebrain neuron differentiation
P	0002376	biological_process	immune system process
P	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
P	0016020	cellular_component	membrane
P	0030670	cellular_component	phagocytic vesicle membrane
P	0042612	cellular_component	MHC class I protein complex
P	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
Q	0000139	cellular_component	Golgi membrane
Q	0001913	biological_process	T cell mediated cytotoxicity
Q	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
Q	0002237	biological_process	response to molecule of bacterial origin
Q	0002376	biological_process	immune system process
Q	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
Q	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
Q	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
Q	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
Q	0002726	biological_process	positive regulation of T cell cytokine production
Q	0005198	molecular_function	structural molecule activity
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005615	cellular_component	extracellular space
Q	0005765	cellular_component	lysosomal membrane
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005788	cellular_component	endoplasmic reticulum lumen
Q	0005794	cellular_component	Golgi apparatus
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0005925	cellular_component	focal adhesion
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0006955	biological_process	immune response
Q	0007608	biological_process	sensory perception of smell
Q	0007611	biological_process	learning or memory
Q	0009897	cellular_component	external side of plasma membrane
Q	0009986	cellular_component	cell surface
Q	0010038	biological_process	response to metal ion
Q	0010977	biological_process	negative regulation of neuron projection development
Q	0012507	cellular_component	ER to Golgi transport vesicle membrane
Q	0016020	cellular_component	membrane
Q	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
Q	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
Q	0023026	molecular_function	MHC class II protein complex binding
Q	0030670	cellular_component	phagocytic vesicle membrane
Q	0031901	cellular_component	early endosome membrane
Q	0031902	cellular_component	late endosome membrane
Q	0031905	cellular_component	early endosome lumen
Q	0033077	biological_process	T cell differentiation in thymus
Q	0033572	biological_process	transferrin transport
Q	0034756	biological_process	regulation of iron ion transport
Q	0034757	biological_process	negative regulation of iron ion transport
Q	0035580	cellular_component	specific granule lumen
Q	0042026	biological_process	protein refolding
Q	0042605	molecular_function	peptide antigen binding
Q	0042612	cellular_component	MHC class I protein complex
Q	0042613	cellular_component	MHC class II protein complex
Q	0042802	molecular_function	identical protein binding
Q	0042803	molecular_function	protein homodimerization activity
Q	0042824	cellular_component	MHC class I peptide loading complex
Q	0045646	biological_process	regulation of erythrocyte differentiation
Q	0048260	biological_process	positive regulation of receptor-mediated endocytosis
Q	0048261	biological_process	negative regulation of receptor-mediated endocytosis
Q	0050680	biological_process	negative regulation of epithelial cell proliferation
Q	0050768	biological_process	negative regulation of neurogenesis
Q	0050778	biological_process	positive regulation of immune response
Q	0050870	biological_process	positive regulation of T cell activation
Q	0051289	biological_process	protein homotetramerization
Q	0055038	cellular_component	recycling endosome membrane
Q	0060586	biological_process	multicellular organismal-level iron ion homeostasis
Q	0070062	cellular_component	extracellular exosome
Q	0071281	biological_process	cellular response to iron ion
Q	0071283	biological_process	cellular response to iron(III) ion
Q	0071316	biological_process	cellular response to nicotine
Q	1904724	cellular_component	tertiary granule lumen
Q	1990000	biological_process	amyloid fibril formation
Q	1990712	cellular_component	HFE-transferrin receptor complex
Q	2000774	biological_process	positive regulation of cellular senescence
Q	2000978	biological_process	negative regulation of forebrain neuron differentiation
S	0002376	biological_process	immune system process
S	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
S	0016020	cellular_component	membrane
S	0030670	cellular_component	phagocytic vesicle membrane
S	0042612	cellular_component	MHC class I protein complex
S	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
T	0000139	cellular_component	Golgi membrane
T	0001913	biological_process	T cell mediated cytotoxicity
T	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
T	0002237	biological_process	response to molecule of bacterial origin
T	0002376	biological_process	immune system process
T	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
T	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
T	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
T	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
T	0002726	biological_process	positive regulation of T cell cytokine production
T	0005198	molecular_function	structural molecule activity
T	0005515	molecular_function	protein binding
T	0005576	cellular_component	extracellular region
T	0005615	cellular_component	extracellular space
T	0005765	cellular_component	lysosomal membrane
T	0005783	cellular_component	endoplasmic reticulum
T	0005788	cellular_component	endoplasmic reticulum lumen
T	0005794	cellular_component	Golgi apparatus
T	0005829	cellular_component	cytosol
T	0005886	cellular_component	plasma membrane
T	0005925	cellular_component	focal adhesion
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0006955	biological_process	immune response
T	0007608	biological_process	sensory perception of smell
T	0007611	biological_process	learning or memory
T	0009897	cellular_component	external side of plasma membrane
T	0009986	cellular_component	cell surface
T	0010038	biological_process	response to metal ion
T	0010977	biological_process	negative regulation of neuron projection development
T	0012507	cellular_component	ER to Golgi transport vesicle membrane
T	0016020	cellular_component	membrane
T	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
T	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
T	0023026	molecular_function	MHC class II protein complex binding
T	0030670	cellular_component	phagocytic vesicle membrane
T	0031901	cellular_component	early endosome membrane
T	0031902	cellular_component	late endosome membrane
T	0031905	cellular_component	early endosome lumen
T	0033077	biological_process	T cell differentiation in thymus
T	0033572	biological_process	transferrin transport
T	0034756	biological_process	regulation of iron ion transport
T	0034757	biological_process	negative regulation of iron ion transport
T	0035580	cellular_component	specific granule lumen
T	0042026	biological_process	protein refolding
T	0042605	molecular_function	peptide antigen binding
T	0042612	cellular_component	MHC class I protein complex
T	0042613	cellular_component	MHC class II protein complex
T	0042802	molecular_function	identical protein binding
T	0042803	molecular_function	protein homodimerization activity
T	0042824	cellular_component	MHC class I peptide loading complex
T	0045646	biological_process	regulation of erythrocyte differentiation
T	0048260	biological_process	positive regulation of receptor-mediated endocytosis
T	0048261	biological_process	negative regulation of receptor-mediated endocytosis
T	0050680	biological_process	negative regulation of epithelial cell proliferation
T	0050768	biological_process	negative regulation of neurogenesis
T	0050778	biological_process	positive regulation of immune response
T	0050870	biological_process	positive regulation of T cell activation
T	0051289	biological_process	protein homotetramerization
T	0055038	cellular_component	recycling endosome membrane
T	0060586	biological_process	multicellular organismal-level iron ion homeostasis
T	0070062	cellular_component	extracellular exosome
T	0071281	biological_process	cellular response to iron ion
T	0071283	biological_process	cellular response to iron(III) ion
T	0071316	biological_process	cellular response to nicotine
T	1904724	cellular_component	tertiary granule lumen
T	1990000	biological_process	amyloid fibril formation
T	1990712	cellular_component	HFE-transferrin receptor complex
T	2000774	biological_process	positive regulation of cellular senescence
T	2000978	biological_process	negative regulation of forebrain neuron differentiation
V	0002376	biological_process	immune system process
V	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
V	0016020	cellular_component	membrane
V	0030670	cellular_component	phagocytic vesicle membrane
V	0042612	cellular_component	MHC class I protein complex
V	0098553	cellular_component	lumenal side of endoplasmic reticulum membrane
W	0000139	cellular_component	Golgi membrane
W	0001913	biological_process	T cell mediated cytotoxicity
W	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
W	0002237	biological_process	response to molecule of bacterial origin
W	0002376	biological_process	immune system process
W	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
W	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
W	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
W	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
W	0002726	biological_process	positive regulation of T cell cytokine production
W	0005198	molecular_function	structural molecule activity
W	0005515	molecular_function	protein binding
W	0005576	cellular_component	extracellular region
W	0005615	cellular_component	extracellular space
W	0005765	cellular_component	lysosomal membrane
W	0005783	cellular_component	endoplasmic reticulum
W	0005788	cellular_component	endoplasmic reticulum lumen
W	0005794	cellular_component	Golgi apparatus
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0005925	cellular_component	focal adhesion
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006955	biological_process	immune response
W	0007608	biological_process	sensory perception of smell
W	0007611	biological_process	learning or memory
W	0009897	cellular_component	external side of plasma membrane
W	0009986	cellular_component	cell surface
W	0010038	biological_process	response to metal ion
W	0010977	biological_process	negative regulation of neuron projection development
W	0012507	cellular_component	ER to Golgi transport vesicle membrane
W	0016020	cellular_component	membrane
W	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
W	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
W	0023026	molecular_function	MHC class II protein complex binding
W	0030670	cellular_component	phagocytic vesicle membrane
W	0031901	cellular_component	early endosome membrane
W	0031902	cellular_component	late endosome membrane
W	0031905	cellular_component	early endosome lumen
W	0033077	biological_process	T cell differentiation in thymus
W	0033572	biological_process	transferrin transport
W	0034756	biological_process	regulation of iron ion transport
W	0034757	biological_process	negative regulation of iron ion transport
W	0035580	cellular_component	specific granule lumen
W	0042026	biological_process	protein refolding
W	0042605	molecular_function	peptide antigen binding
W	0042612	cellular_component	MHC class I protein complex
W	0042613	cellular_component	MHC class II protein complex
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0042824	cellular_component	MHC class I peptide loading complex
W	0045646	biological_process	regulation of erythrocyte differentiation
W	0048260	biological_process	positive regulation of receptor-mediated endocytosis
W	0048261	biological_process	negative regulation of receptor-mediated endocytosis
W	0050680	biological_process	negative regulation of epithelial cell proliferation
W	0050768	biological_process	negative regulation of neurogenesis
W	0050778	biological_process	positive regulation of immune response
W	0050870	biological_process	positive regulation of T cell activation
W	0051289	biological_process	protein homotetramerization
W	0055038	cellular_component	recycling endosome membrane
W	0060586	biological_process	multicellular organismal-level iron ion homeostasis
W	0070062	cellular_component	extracellular exosome
W	0071281	biological_process	cellular response to iron ion
W	0071283	biological_process	cellular response to iron(III) ion
W	0071316	biological_process	cellular response to nicotine
W	1904724	cellular_component	tertiary granule lumen
W	1990000	biological_process	amyloid fibril formation
W	1990712	cellular_component	HFE-transferrin receptor complex
W	2000774	biological_process	positive regulation of cellular senescence
W	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH

Chain	Residue	Details
B	TYR78-HIS84
A	TYR258-HIS264

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	MOD_RES: Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280

Chain	Residue	Details
B	GLN2
E	GLN2
H	GLN2
K	GLN2
N	GLN2
Q	GLN2
T	GLN2
W	GLN2

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	CARBOHYD: N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443

Chain	Residue	Details
B	ILE1
E	ILE1
H	ILE1
K	ILE1
N	ILE1
Q	ILE1
T	ILE1
W	ILE1

---

site_id	SWS_FT_FI3
Number of Residues	48
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443

Chain	Residue	Details
B	LYS19
E	LYS58
E	LYS91
E	LYS94
H	LYS19
H	LYS41
H	LYS48
H	LYS58
H	LYS91
H	LYS94
K	LYS19
B	LYS41
K	LYS41
K	LYS48
K	LYS58
K	LYS91
K	LYS94
N	LYS19
N	LYS41
N	LYS48
N	LYS58
N	LYS91
B	LYS48
N	LYS94
Q	LYS19
Q	LYS41
Q	LYS48
Q	LYS58
Q	LYS91
Q	LYS94
T	LYS19
T	LYS41
T	LYS48
B	LYS58
T	LYS58
T	LYS91
T	LYS94
W	LYS19
W	LYS41
W	LYS48
W	LYS58
W	LYS91
W	LYS94
B	LYS91
B	LYS94
E	LYS19
E	LYS41
E	LYS48

---