5EZ5

Crystal structure of active Rab11A (S20V) in complex with GTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 201

Chain	Residue
A	SER25
A	THR43
A	GTP202
A	HOH301

---

site_id	AC2
Number of Residues	24
Details	binding site for residue GTP A 202

Chain	Residue
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38
A	SER40
A	SER42
A	THR43
A	ALA68
A	GLY69
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	ALA155
A	LEU156
A	MG201
A	HOH301
A	VAL20
A	GLY21
A	VAL22
A	GLY23
A	LYS24

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG B 201

Chain	Residue
B	SER25
B	THR43
B	ASP66
B	GTP202
B	HOH301

---

site_id	AC4
Number of Residues	24
Details	binding site for residue GTP B 202

Chain	Residue
B	VAL20
B	GLY21
B	VAL22
B	GLY23
B	LYS24
B	SER25
B	ASN26
B	PHE36
B	ASN37
B	LEU38
B	SER40
B	SER42
B	THR43
B	ALA68
B	GLY69
B	ASN124
B	LYS125
B	ASP127
B	SER154
B	ALA155
B	LEU156
B	MG201
B	HOH301
B	HOH303

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837192","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16905101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17007872","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17030804","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D7C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GZH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---