5EWX

Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0019865	molecular_function	immunoglobulin binding
B	0003796	molecular_function	lysozyme activity
B	0009253	biological_process	peptidoglycan catabolic process
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0019865	molecular_function	immunoglobulin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue EYC A 1301

Chain	Residue
A	CYS40
B	EYC1301
A	GLN1237
A	CYS1258
A	ALA1262
A	ALA1265
A	GLN1266
A	HOH1424
B	SER44
B	GLN1266

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site_id	AC2
Number of Residues	9
Details	binding site for residue EYC B 1301

Chain	Residue
A	SER44
A	EYC1301
B	CYS40
B	GLN1237
B	CYS1258
B	ALA1265
B	GLN1266
B	HOH1406
B	HOH1422

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098

Chain	Residue	Details
A	GLU11
B	GLU11

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098

Chain	Residue	Details
A	ASP20
B	ASP20

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:8266098

Chain	Residue	Details
A	LEU32
A	PHE104
B	LEU32
B	PHE104

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000303|PubMed:7831309

Chain	Residue	Details
A	SER117
A	ASN132
B	SER117
B	ASN132

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 921

Chain	Residue	Details
A	GLU11	proton shuttle (general acid/base)
A	ASP20	covalent catalysis

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site_id	MCSA2
Number of Residues	2
Details	M-CSA 921

Chain	Residue	Details
B	GLU11	proton shuttle (general acid/base)
B	ASP20	covalent catalysis

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