5EUD
S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
A | 0008117 | molecular_function | sphinganine-1-phosphate aldolase activity |
A | 0016829 | molecular_function | lyase activity |
A | 0016830 | molecular_function | carbon-carbon lyase activity |
A | 0019752 | biological_process | carboxylic acid metabolic process |
A | 0030149 | biological_process | sphingolipid catabolic process |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 0042802 | molecular_function | identical protein binding |
B | 0004058 | molecular_function | aromatic-L-amino-acid decarboxylase activity |
B | 0008117 | molecular_function | sphinganine-1-phosphate aldolase activity |
B | 0016829 | molecular_function | lyase activity |
B | 0016830 | molecular_function | carbon-carbon lyase activity |
B | 0019752 | biological_process | carboxylic acid metabolic process |
B | 0030149 | biological_process | sphingolipid catabolic process |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue PO4 A 601 |
Chain | Residue |
A | ALA103 |
A | TYR105 |
A | LLP311 |
A | HOH705 |
A | HOH732 |
A | HOH775 |
B | ASN126 |
B | HIS129 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue 5S6 A 602 |
Chain | Residue |
A | PHE249 |
A | LLP311 |
A | VAL496 |
A | PHE500 |
B | PRO127 |
B | LEU128 |
B | PRO130 |
B | TRP340 |
B | GLY342 |
B | ILE344 |
B | TYR345 |
B | ALA346 |
B | HOH714 |
A | HIS201 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue 5S6 A 603 |
Chain | Residue |
A | LEU128 |
A | PRO130 |
A | TRP340 |
A | GLY342 |
A | ILE344 |
A | TYR345 |
A | ALA346 |
A | HOH712 |
A | HOH747 |
B | HIS201 |
B | PHE249 |
B | LLP311 |
B | SER497 |
B | PHE500 |
site_id | AC4 |
Number of Residues | 12 |
Details | binding site for residue PO4 B 601 |
Chain | Residue |
A | ASN126 |
A | LEU128 |
A | HIS129 |
A | HOH712 |
A | HOH745 |
B | ALA103 |
B | TYR105 |
B | LLP311 |
B | HOH703 |
B | HOH738 |
B | HOH741 |
B | HOH800 |