5ETY

Crystal Structure of human Tankyrase-1 bound to K-756

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ poly-ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+ poly-ADP-ribosyltransferase activity
C	0003950	molecular_function	NAD+ poly-ADP-ribosyltransferase activity
D	0003950	molecular_function	NAD+ poly-ADP-ribosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1401

Chain	Residue
A	CYS1234
A	HIS1237
A	CYS1242
A	CYS1245

---

site_id	AC2
Number of Residues	15
Details	binding site for residue K56 A 1402

Chain	Residue
A	GLY1196
A	ASP1198
A	HIS1201
A	GLY1211
A	ILE1212
A	TYR1213
A	TYR1224
A	ILE1228
A	HOH1507
A	HOH1511
A	HIS1184
A	GLY1185
A	PHE1188
A	ALA1191
A	ILE1192

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 1401

Chain	Residue
B	CYS1234
B	HIS1237
B	CYS1242
B	CYS1245

---

site_id	AC4
Number of Residues	11
Details	binding site for residue K56 B 1402

Chain	Residue
B	HIS1184
B	GLY1185
B	PHE1188
B	ILE1192
B	GLY1196
B	ASP1198
B	HIS1201
B	GLY1211
B	ILE1212
B	TYR1213
B	ILE1228

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 1401

Chain	Residue
C	CYS1234
C	HIS1237
C	CYS1242
C	CYS1245

---

site_id	AC6
Number of Residues	11
Details	binding site for residue K56 C 1402

Chain	Residue
C	HIS1184
C	GLY1185
C	SER1186
C	PHE1188
C	ALA1191
C	GLY1196
C	ASP1198
C	HIS1201
C	GLY1211
C	TYR1213
C	ILE1228

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 1401

Chain	Residue
D	CYS1234
D	HIS1237
D	CYS1242
D	CYS1245

---

site_id	AC8
Number of Residues	13
Details	binding site for residue K56 D 1402

Chain	Residue
D	HIS1184
D	SER1186
D	PHE1188
D	ALA1191
D	ILE1192
D	GLY1196
D	ASP1198
D	HIS1201
D	ALA1202
D	GLY1211
D	TYR1213
D	ILE1228
D	HOH1501

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18436240","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2RF5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UDD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UH4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DVI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4I9I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4K4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KRS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LI6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MSG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MSK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MT9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N3R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N4V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TOS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W6E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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