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5EPM

Ceratotoxin variant in complex with specific antibody Fab fragment

Functional Information from GO Data
ChainGOidnamespacecontents
C0005246molecular_functioncalcium channel regulator activity
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0008200molecular_functionion channel inhibitor activity
C0017080molecular_functionsodium channel regulator activity
C0019871molecular_functionsodium channel inhibitor activity
C0044493biological_processvenom-mediated inhibition of voltage-gated sodium channel activity
C0090729molecular_functiontoxin activity
C0099106molecular_functionion channel regulator activity
D0005246molecular_functioncalcium channel regulator activity
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0008200molecular_functionion channel inhibitor activity
D0017080molecular_functionsodium channel regulator activity
D0019871molecular_functionsodium channel inhibitor activity
D0044493biological_processvenom-mediated inhibition of voltage-gated sodium channel activity
D0090729molecular_functiontoxin activity
D0099106molecular_functionion channel regulator activity
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
BTYR197-HIS203

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues64
DetailsPeptide: {"description":"Beta-theraphotoxin-Cm1a","featureId":"PRO_0000045000","evidences":[{"source":"PubMed","id":"16267209","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsModified residue: {"description":"Leucine amide","evidences":[{"source":"PubMed","id":"16267209","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

243911

PDB entries from 2025-10-29

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