5EOM
Structure of full-length human MAB21L1 with bound CTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001654 | biological_process | eye development |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0009653 | biological_process | anatomical structure morphogenesis |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0001654 | biological_process | eye development |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0009653 | biological_process | anatomical structure morphogenesis |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0001654 | biological_process | eye development |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0009653 | biological_process | anatomical structure morphogenesis |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0001654 | biological_process | eye development |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005525 | molecular_function | GTP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0009653 | biological_process | anatomical structure morphogenesis |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0001654 | biological_process | eye development |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005525 | molecular_function | GTP binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0009653 | biological_process | anatomical structure morphogenesis |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016779 | molecular_function | nucleotidyltransferase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0001654 | biological_process | eye development |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005525 | molecular_function | GTP binding |
| F | 0005634 | cellular_component | nucleus |
| F | 0009653 | biological_process | anatomical structure morphogenesis |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016779 | molecular_function | nucleotidyltransferase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0001654 | biological_process | eye development |
| G | 0005515 | molecular_function | protein binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005525 | molecular_function | GTP binding |
| G | 0005634 | cellular_component | nucleus |
| G | 0009653 | biological_process | anatomical structure morphogenesis |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016779 | molecular_function | nucleotidyltransferase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0001654 | biological_process | eye development |
| H | 0005515 | molecular_function | protein binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005525 | molecular_function | GTP binding |
| H | 0005634 | cellular_component | nucleus |
| H | 0009653 | biological_process | anatomical structure morphogenesis |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016779 | molecular_function | nucleotidyltransferase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0001654 | biological_process | eye development |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005525 | molecular_function | GTP binding |
| I | 0005634 | cellular_component | nucleus |
| I | 0009653 | biological_process | anatomical structure morphogenesis |
| I | 0016740 | molecular_function | transferase activity |
| I | 0016779 | molecular_function | nucleotidyltransferase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0000166 | molecular_function | nucleotide binding |
| J | 0001654 | biological_process | eye development |
| J | 0005515 | molecular_function | protein binding |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005525 | molecular_function | GTP binding |
| J | 0005634 | cellular_component | nucleus |
| J | 0009653 | biological_process | anatomical structure morphogenesis |
| J | 0016740 | molecular_function | transferase activity |
| J | 0016779 | molecular_function | nucleotidyltransferase activity |
| J | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CIT A 401 |
| Chain | Residue |
| A | TYR10 |
| A | HIS11 |
| A | LYS14 |
| A | LYS354 |
| A | GLU357 |
| D | TRP343 |
| D | ARG347 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue TMO A 402 |
| Chain | Residue |
| A | PRO190 |
| A | ILE192 |
| A | PRO195 |
| A | PRO188 |
| A | LEU189 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue CTP A 403 |
| Chain | Residue |
| A | ARG23 |
| A | LYS24 |
| A | ILE27 |
| A | ILE31 |
| A | ARG62 |
| A | TYR63 |
| A | LEU66 |
| A | VAL68 |
| A | LYS248 |
| A | SER252 |
| A | LYS255 |
| A | HOH502 |
| A | HOH504 |
| A | HOH505 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue CIT B 401 |
| Chain | Residue |
| B | LYS7 |
| B | TYR10 |
| B | HIS11 |
| B | LYS14 |
| B | LYS354 |
| C | TRP343 |
| C | ARG344 |
| C | ARG347 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue CTP B 402 |
| Chain | Residue |
| B | ARG23 |
| B | LYS24 |
| B | ILE27 |
| B | ILE31 |
| B | ASN61 |
| B | ARG62 |
| B | TYR63 |
| B | LEU66 |
| B | VAL68 |
| B | SER252 |
| B | LYS255 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CIT D 401 |
| Chain | Residue |
| D | TYR10 |
| D | HIS11 |
| D | LYS14 |
| D | LYS354 |
| F | LYS340 |
| F | ARG347 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue CTP D 402 |
| Chain | Residue |
| D | ARG23 |
| D | LYS24 |
| D | ILE31 |
| D | ARG62 |
| D | TYR63 |
| D | LEU66 |
| D | VAL68 |
| D | LYS248 |
| D | SER252 |
| D | LYS255 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue CIT E 401 |
| Chain | Residue |
| E | TYR10 |
| E | HIS11 |
| E | LYS14 |
| E | LYS354 |
| E | GLU357 |
| G | TRP343 |
| G | ARG344 |
| G | ARG347 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue CTP E 402 |
| Chain | Residue |
| E | ARG23 |
| E | LYS24 |
| E | ILE27 |
| E | ILE31 |
| E | ARG62 |
| E | TYR63 |
| E | LEU66 |
| E | VAL68 |
| E | LYS248 |
| E | SER252 |
| E | LYS255 |
| E | HOH501 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue CIT F 401 |
| Chain | Residue |
| B | LYS340 |
| B | TRP343 |
| B | ARG347 |
| F | TYR10 |
| F | HIS11 |
| F | LYS14 |
| F | LYS354 |
| F | HOH503 |
| F | HOH525 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue TMO F 402 |
| Chain | Residue |
| F | SER144 |
| F | TYR145 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue CTP F 403 |
| Chain | Residue |
| F | LEU66 |
| F | VAL68 |
| F | LYS248 |
| F | SER252 |
| F | LYS255 |
| F | HOH510 |
| F | ARG23 |
| F | LYS24 |
| F | ILE27 |
| F | ILE31 |
| F | ASN61 |
| F | ARG62 |
| F | TYR63 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CIT G 401 |
| Chain | Residue |
| G | TYR10 |
| G | HIS11 |
| G | LYS14 |
| G | LYS354 |
| I | LYS340 |
| I | TRP343 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue CTP G 402 |
| Chain | Residue |
| G | ARG23 |
| G | LYS24 |
| G | ILE31 |
| G | ARG62 |
| G | TYR63 |
| G | LEU66 |
| G | VAL68 |
| G | SER252 |
| G | LYS255 |
| G | HOH507 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CIT H 401 |
| Chain | Residue |
| H | LYS340 |
| H | ARG347 |
| J | TYR10 |
| J | HIS11 |
| J | LYS354 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue CIT H 402 |
| Chain | Residue |
| E | LYS340 |
| E | TRP343 |
| H | TYR10 |
| H | HIS11 |
| H | LYS354 |
| H | GLU357 |
| site_id | AD8 |
| Number of Residues | 13 |
| Details | binding site for residue CTP H 403 |
| Chain | Residue |
| H | ARG23 |
| H | LYS24 |
| H | ALA28 |
| H | ARG62 |
| H | TYR63 |
| H | LEU66 |
| H | VAL68 |
| H | LYS248 |
| H | SER252 |
| H | LYS255 |
| H | HOH502 |
| H | HOH504 |
| H | HOH505 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue CIT I 401 |
| Chain | Residue |
| I | TYR10 |
| I | LYS14 |
| I | LYS354 |
| I | HOH502 |
| I | HOH508 |
| J | LYS340 |
| J | TRP343 |
| J | ARG347 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue CTP I 402 |
| Chain | Residue |
| I | ARG23 |
| I | LYS24 |
| I | ALA28 |
| I | ILE31 |
| I | ARG62 |
| I | TYR63 |
| I | LYS248 |
| I | SER252 |
| I | LYS255 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue CTP J 401 |
| Chain | Residue |
| J | ARG23 |
| J | LYS24 |
| J | ALA28 |
| J | ILE31 |
| J | ARG32 |
| J | TYR63 |
| J | LEU66 |
| J | VAL68 |
| J | LYS248 |
| J | SER252 |
| J | LYS255 |
| J | HOH501 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue CIT C 401 |
| Chain | Residue |
| A | LYS340 |
| A | TRP343 |
| A | ARG344 |
| C | TYR10 |
| C | HIS11 |
| C | LYS14 |
| C | LYS354 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue TMO C 402 |
| Chain | Residue |
| C | THR72 |
| C | ARG161 |
| C | ARG165 |
| C | VAL167 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue TMO C 403 |
| Chain | Residue |
| C | PRO188 |
| C | LEU189 |
| C | PRO190 |
| C | ILE192 |
| site_id | AE6 |
| Number of Residues | 11 |
| Details | binding site for residue CTP C 404 |
| Chain | Residue |
| C | ARG23 |
| C | LYS24 |
| C | ILE27 |
| C | ILE31 |
| C | ARG62 |
| C | TYR63 |
| C | LEU66 |
| C | VAL68 |
| C | LYS248 |
| C | SER252 |
| C | LYS255 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27271801","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EOM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8N884","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
