5ELG
The structure of DHAR1 from Arabidopsis thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000325 | cellular_component | plant-type vacuole |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006952 | biological_process | defense response |
| A | 0009507 | cellular_component | chloroplast |
| A | 0009570 | cellular_component | chloroplast stroma |
| A | 0009610 | biological_process | response to symbiotic fungus |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0009753 | biological_process | response to jasmonic acid |
| A | 0010043 | biological_process | response to zinc ion |
| A | 0010193 | biological_process | response to ozone |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019852 | biological_process | L-ascorbic acid metabolic process |
| A | 0033355 | biological_process | ascorbate glutathione cycle |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0034702 | cellular_component | monoatomic ion channel complex |
| A | 0043903 | biological_process | regulation of biological process involved in symbiotic interaction |
| A | 0045174 | molecular_function | glutathione dehydrogenase (ascorbate) activity |
| A | 0048046 | cellular_component | apoplast |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0080151 | biological_process | positive regulation of salicylic acid mediated signaling pathway |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 0140547 | biological_process | acquisition of seed longevity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | LYS8 |
| A | ASP19 |
| A | GLY206 |
| A | TRP207 |
| A | LYS210 |
| A | HOH452 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue GSH A 302 |
| Chain | Residue |
| A | LYS59 |
| A | VAL60 |
| A | PRO61 |
| A | ASP72 |
| A | SER73 |
| A | HOH415 |
| A | HOH469 |
| A | HOH529 |
| A | HOH544 |
| A | HOH549 |
| A | CYS20 |
| A | PHE22 |
| A | LYS47 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | HIS16 |
| A | LEU17 |
| A | LYS38 |
| A | GLU199 |
| A | HOH490 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | ASP138 |
| A | GLY166 |
| A | SER170 |
| A | SER172 |
| A | HOH441 |
| A | HOH555 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | ASN101 |
| A | GLY104 |
| A | HOH421 |
| A | HOH443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | GLU32 |
| A | PHE141 |
| A | ARG146 |
| A | VAL147 |
| A | LEU190 |
| A | HOH592 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 73 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 129 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Motif: {"description":"Glutathione-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Copper-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q65XA0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q65XA0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2015","submissionDatabase":"PDB data bank","title":"Arabidopsis thaliana DHAR1 apo structure.","authors":["Menault M.","Roszak A.W.","Lapthorn A.J."]}},{"source":"PDB","id":"5ELG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-glutathionyl cysteine","evidences":[{"source":"PubMed","id":"12077129","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16055689","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
