5EJ8
EcMenD-ThDP-Mn2+ complex structure soaked with 2-ketoglutarate for 2 min
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0009234 | biological_process | menaquinone biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0044281 | biological_process | small molecule metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0009234 | biological_process | menaquinone biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0044281 | biological_process | small molecule metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0009234 | biological_process | menaquinone biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0030976 | molecular_function | thiamine pyrophosphate binding |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0044281 | biological_process | small molecule metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0009234 | biological_process | menaquinone biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0030976 | molecular_function | thiamine pyrophosphate binding |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0044281 | biological_process | small molecule metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0009234 | biological_process | menaquinone biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0030145 | molecular_function | manganese ion binding |
| E | 0030976 | molecular_function | thiamine pyrophosphate binding |
| E | 0042803 | molecular_function | protein homodimerization activity |
| E | 0044281 | biological_process | small molecule metabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0009234 | biological_process | menaquinone biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0030145 | molecular_function | manganese ion binding |
| F | 0030976 | molecular_function | thiamine pyrophosphate binding |
| F | 0042803 | molecular_function | protein homodimerization activity |
| F | 0044281 | biological_process | small molecule metabolic process |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0009234 | biological_process | menaquinone biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0030145 | molecular_function | manganese ion binding |
| G | 0030976 | molecular_function | thiamine pyrophosphate binding |
| G | 0042803 | molecular_function | protein homodimerization activity |
| G | 0044281 | biological_process | small molecule metabolic process |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0009234 | biological_process | menaquinone biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0030145 | molecular_function | manganese ion binding |
| H | 0030976 | molecular_function | thiamine pyrophosphate binding |
| H | 0042803 | molecular_function | protein homodimerization activity |
| H | 0044281 | biological_process | small molecule metabolic process |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0070204 | molecular_function | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue TD6 A 601 |
| Chain | Residue |
| A | ASN390 |
| A | GLY441 |
| A | ASP442 |
| A | LEU443 |
| A | SER444 |
| A | TYR447 |
| A | ASN469 |
| A | GLY471 |
| A | GLY472 |
| A | GLN473 |
| A | ILE474 |
| A | SER391 |
| A | MN602 |
| A | MG603 |
| A | HOH796 |
| A | HOH901 |
| A | HOH990 |
| B | PRO30 |
| B | GLU55 |
| B | THR81 |
| B | ALA82 |
| B | ASN117 |
| A | LEU392 |
| B | GLN118 |
| B | FMT601 |
| A | ARG395 |
| A | ARG413 |
| A | SER416 |
| A | GLY417 |
| A | ILE418 |
| A | ASP419 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 602 |
| Chain | Residue |
| A | ASP442 |
| A | ASN469 |
| A | GLY471 |
| A | TD6601 |
| A | HOH901 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | ASP442 |
| A | ASN469 |
| A | GLY471 |
| A | TD6601 |
| A | HOH901 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | HIS49 |
| A | HIS50 |
| A | THR51 |
| A | ARG430 |
| A | LEU454 |
| A | GLN457 |
| A | HOH746 |
| A | HOH880 |
| B | HOH869 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | ARG364 |
| A | HIS374 |
| A | CYS377 |
| A | ASP378 |
| A | HOH950 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | HOH703 |
| A | HOH704 |
| A | HOH715 |
| A | HOH1073 |
| A | HOH1127 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 607 |
| Chain | Residue |
| A | LYS70 |
| A | ASP311 |
| A | HOH718 |
| A | HOH828 |
| A | HOH914 |
| A | HOH1016 |
| A | HOH1137 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 608 |
| Chain | Residue |
| A | ALA241 |
| A | GLN242 |
| A | TRP246 |
| A | HOH851 |
| A | HOH958 |
| A | HOH1109 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue FMT A 609 |
| Chain | Residue |
| A | LYS220 |
| A | LEU244 |
| A | GLY245 |
| A | TRP246 |
| A | ARG342 |
| A | GLN343 |
| A | TRP345 |
| A | HOH897 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | GLN457 |
| A | VAL458 |
| A | HOH1158 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | GLY94 |
| A | SER128 |
| A | HIS129 |
| A | THR131 |
| A | HOH702 |
| A | HOH1008 |
| B | ARG121 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | ALA405 |
| A | GLY406 |
| A | TYR407 |
| A | HOH810 |
| A | HOH865 |
| A | HOH1050 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 613 |
| Chain | Residue |
| A | LEU295 |
| A | EDO614 |
| A | HOH730 |
| A | HOH762 |
| A | HOH777 |
| A | HOH784 |
| B | GLY115 |
| B | ASN117 |
| A | SER288 |
| A | LEU289 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue EDO A 614 |
| Chain | Residue |
| A | LEU289 |
| A | THR290 |
| A | LEU295 |
| A | ARG395 |
| A | ARG413 |
| A | EDO613 |
| A | HOH719 |
| A | HOH762 |
| A | HOH829 |
| A | HOH1176 |
| B | ASN117 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 615 |
| Chain | Residue |
| A | GLU207 |
| A | ASP332 |
| A | GLU335 |
| A | LEU336 |
| A | HOH1115 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue FMT A 616 |
| Chain | Residue |
| A | GLY31 |
| A | SER32 |
| A | ARG33 |
| A | THR78 |
| A | ARG107 |
| A | GLN118 |
| A | HOH1040 |
| B | TD6602 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue FMT A 617 |
| Chain | Residue |
| A | ALA127 |
| A | SER128 |
| A | HIS129 |
| A | HOH710 |
| B | ARG121 |
| B | PRO123 |
| B | MET125 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 618 |
| Chain | Residue |
| A | ARG121 |
| A | PRO123 |
| A | MET125 |
| B | ALA127 |
| B | SER128 |
| B | HIS129 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue FMT B 601 |
| Chain | Residue |
| A | TD6601 |
| B | GLY31 |
| B | SER32 |
| B | ARG33 |
| B | THR78 |
| B | ARG107 |
| B | GLN118 |
| B | HOH1052 |
| site_id | AE2 |
| Number of Residues | 31 |
| Details | binding site for residue TD6 B 602 |
| Chain | Residue |
| A | PRO30 |
| A | GLU55 |
| A | THR81 |
| A | ALA82 |
| A | ASN117 |
| A | GLN118 |
| A | FMT616 |
| B | ASN390 |
| B | SER391 |
| B | LEU392 |
| B | ARG395 |
| B | ARG413 |
| B | SER416 |
| B | GLY417 |
| B | ILE418 |
| B | ASP419 |
| B | GLY441 |
| B | ASP442 |
| B | LEU443 |
| B | SER444 |
| B | TYR447 |
| B | ASN469 |
| B | GLY471 |
| B | GLY472 |
| B | GLN473 |
| B | ILE474 |
| B | MN603 |
| B | MG604 |
| B | HOH794 |
| B | HOH802 |
| B | HOH986 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 603 |
| Chain | Residue |
| B | ASP442 |
| B | ASN469 |
| B | GLY471 |
| B | TD6602 |
| B | HOH794 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 604 |
| Chain | Residue |
| B | ASP442 |
| B | ASN469 |
| B | GLY471 |
| B | TD6602 |
| B | HOH794 |
| site_id | AE5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | HIS49 |
| B | HIS50 |
| B | THR51 |
| B | ARG430 |
| B | LEU454 |
| B | GLN457 |
| B | HOH770 |
| B | HOH817 |
| B | HOH931 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 606 |
| Chain | Residue |
| A | GLU340 |
| B | ASN513 |
| B | TRP514 |
| B | GLN515 |
| B | HOH748 |
| B | HOH762 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 607 |
| Chain | Residue |
| B | ASP311 |
| B | HOH875 |
| B | HOH895 |
| B | HOH953 |
| B | HOH1130 |
| B | HOH1322 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue FMT B 608 |
| Chain | Residue |
| B | ALA241 |
| B | GLN242 |
| B | TRP246 |
| B | FMT609 |
| B | HOH730 |
| B | HOH800 |
| B | HOH1116 |
| B | HOH1126 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue FMT B 609 |
| Chain | Residue |
| B | LEU260 |
| B | FMT608 |
| B | HOH800 |
| B | HOH1171 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 610 |
| Chain | Residue |
| B | HIS25 |
| B | SER69 |
| B | GLN71 |
| B | HOH855 |
| B | HOH1020 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 611 |
| Chain | Residue |
| B | PRO173 |
| B | LEU174 |
| B | TYR175 |
| B | HOH784 |
| B | HOH906 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 612 |
| Chain | Residue |
| B | GLN383 |
| B | GLY433 |
| B | LYS434 |
| B | PRO435 |
| B | HOH707 |
| B | HOH880 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 613 |
| Chain | Residue |
| A | ASN117 |
| A | HOH774 |
| B | LEU289 |
| B | THR290 |
| B | LEU295 |
| B | ARG413 |
| site_id | AF5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 601 |
| Chain | Residue |
| B | PRO137 |
| B | ARG138 |
| B | HOH917 |
| C | PRO137 |
| C | ARG138 |
| C | HOH704 |
| C | HOH834 |
| C | HOH1026 |
| site_id | AF6 |
| Number of Residues | 30 |
| Details | binding site for residue TD6 C 602 |
| Chain | Residue |
| C | ASN390 |
| C | SER391 |
| C | LEU392 |
| C | ARG395 |
| C | ARG413 |
| C | SER416 |
| C | GLY417 |
| C | ILE418 |
| C | ASP419 |
| C | GLY441 |
| C | ASP442 |
| C | LEU443 |
| C | SER444 |
| C | TYR447 |
| C | ASN469 |
| C | GLY471 |
| C | GLY472 |
| C | GLN473 |
| C | ILE474 |
| C | MN603 |
| C | MG604 |
| C | HOH800 |
| C | HOH859 |
| C | HOH973 |
| D | PRO30 |
| D | GLU55 |
| D | THR81 |
| D | ASN117 |
| D | GLN118 |
| D | FMT610 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 603 |
| Chain | Residue |
| C | ASP442 |
| C | ASN469 |
| C | GLY471 |
| C | TD6602 |
| C | HOH859 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 604 |
| Chain | Residue |
| C | ASP442 |
| C | ASN469 |
| C | GLY471 |
| C | TD6602 |
| C | HOH859 |
| site_id | AF9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 605 |
| Chain | Residue |
| C | HIS49 |
| C | HIS50 |
| C | THR51 |
| C | ARG430 |
| C | GLN457 |
| C | HOH733 |
| C | HOH788 |
| C | HOH791 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue TRS C 606 |
| Chain | Residue |
| C | GLU16 |
| C | ASN44 |
| C | SER45 |
| C | ALA46 |
| C | HOH757 |
| C | HOH760 |
| site_id | AG2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO C 607 |
| Chain | Residue |
| C | THR96 |
| C | ARG228 |
| C | ASP311 |
| C | MG608 |
| C | HOH761 |
| C | HOH790 |
| C | HOH889 |
| C | HOH995 |
| C | HOH1087 |
| C | HOH1104 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 608 |
| Chain | Residue |
| C | ASP311 |
| C | EDO607 |
| C | HOH790 |
| C | HOH1087 |
| C | HOH1104 |
| site_id | AG4 |
| Number of Residues | 7 |
| Details | binding site for residue FMT C 609 |
| Chain | Residue |
| C | ALA241 |
| C | GLN242 |
| C | TRP246 |
| C | EDO610 |
| C | HOH795 |
| C | HOH941 |
| C | HOH1072 |
| site_id | AG5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 610 |
| Chain | Residue |
| C | ALA238 |
| C | GLN242 |
| C | LEU248 |
| C | PRO259 |
| C | FMT609 |
| C | HOH711 |
| C | HOH773 |
| C | HOH1080 |
| site_id | AG6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 611 |
| Chain | Residue |
| C | MET229 |
| C | SER230 |
| C | ALA231 |
| C | GLN255 |
| C | VAL409 |
| C | TYR410 |
| C | HOH778 |
| C | HOH950 |
| site_id | AG7 |
| Number of Residues | 6 |
| Details | binding site for residue FMT C 612 |
| Chain | Residue |
| C | GLU505 |
| C | LEU506 |
| C | LYS507 |
| C | THR529 |
| C | THR530 |
| C | HOH989 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 613 |
| Chain | Residue |
| C | HIS21 |
| C | LYS70 |
| C | GLN71 |
| C | LYS99 |
| C | HOH1038 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue FMT C 614 |
| Chain | Residue |
| C | LYS210 |
| C | GLN211 |
| C | ARG212 |
| C | ASP213 |
| C | HOH793 |
| site_id | AH1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO C 615 |
| Chain | Residue |
| C | LEU289 |
| C | THR290 |
| C | ARG395 |
| C | ARG413 |
| C | EDO616 |
| C | HOH715 |
| C | HOH721 |
| D | ASN117 |
| D | HOH740 |
| site_id | AH2 |
| Number of Residues | 11 |
| Details | binding site for residue EDO C 616 |
| Chain | Residue |
| C | SER288 |
| C | LEU289 |
| C | LEU295 |
| C | EDO615 |
| C | HOH738 |
| C | HOH748 |
| C | HOH806 |
| D | GLY115 |
| D | ALA116 |
| D | ASN117 |
| D | HOH740 |
| site_id | AH3 |
| Number of Residues | 8 |
| Details | binding site for residue FMT C 617 |
| Chain | Residue |
| C | GLY31 |
| C | SER32 |
| C | ARG33 |
| C | THR78 |
| C | ARG107 |
| C | GLN118 |
| C | HOH1023 |
| D | TD6602 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue FMT D 601 |
| Chain | Residue |
| C | HIS49 |
| C | HOH1050 |
| D | ARG487 |
| D | HOH1081 |
| site_id | AH5 |
| Number of Residues | 31 |
| Details | binding site for residue TD6 D 602 |
| Chain | Residue |
| C | PRO30 |
| C | GLU55 |
| C | THR81 |
| C | ALA82 |
| C | ASN117 |
| C | GLN118 |
| C | FMT617 |
| D | ASN390 |
| D | SER391 |
| D | LEU392 |
| D | ARG395 |
| D | ARG413 |
| D | SER416 |
| D | GLY417 |
| D | ILE418 |
| D | ASP419 |
| D | GLY441 |
| D | ASP442 |
| D | LEU443 |
| D | SER444 |
| D | TYR447 |
| D | ASN469 |
| D | GLY471 |
| D | GLY472 |
| D | GLN473 |
| D | ILE474 |
| D | MN603 |
| D | MG604 |
| D | HOH825 |
| D | HOH870 |
| D | HOH958 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 603 |
| Chain | Residue |
| D | ASP442 |
| D | ASN469 |
| D | GLY471 |
| D | TD6602 |
| D | HOH870 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 604 |
| Chain | Residue |
| D | ASP442 |
| D | ASN469 |
| D | GLY471 |
| D | TD6602 |
| D | HOH870 |
| site_id | AH8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 605 |
| Chain | Residue |
| D | HIS49 |
| D | HIS50 |
| D | THR51 |
| D | ARG430 |
| D | LEU454 |
| D | HOH730 |
| D | HOH746 |
| D | HOH801 |
| site_id | AH9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 606 |
| Chain | Residue |
| D | GLU16 |
| D | HOH759 |
| D | HOH933 |
| D | HOH1060 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue FMT D 607 |
| Chain | Residue |
| D | PRO173 |
| D | LEU174 |
| D | TYR175 |
| D | HOH717 |
| D | HOH750 |
| site_id | AI2 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 608 |
| Chain | Residue |
| D | ASP311 |
| D | HOH727 |
| D | HOH846 |
| D | HOH981 |
| D | HOH989 |
| D | HOH1215 |
| site_id | AI3 |
| Number of Residues | 6 |
| Details | binding site for residue FMT D 609 |
| Chain | Residue |
| D | PRO123 |
| D | GLY124 |
| D | ILE134 |
| D | SER135 |
| D | HIS165 |
| D | ASN167 |
| site_id | AI4 |
| Number of Residues | 8 |
| Details | binding site for residue FMT D 610 |
| Chain | Residue |
| C | TD6602 |
| D | GLY31 |
| D | SER32 |
| D | ARG33 |
| D | THR78 |
| D | ARG107 |
| D | GLN118 |
| D | HOH962 |
| site_id | AI5 |
| Number of Residues | 11 |
| Details | binding site for residue EDO D 611 |
| Chain | Residue |
| C | ASN117 |
| D | LEU289 |
| D | THR290 |
| D | LEU295 |
| D | ARG395 |
| D | ARG413 |
| D | FMT612 |
| D | HOH729 |
| D | HOH745 |
| D | HOH876 |
| D | HOH983 |
| site_id | AI6 |
| Number of Residues | 8 |
| Details | binding site for residue FMT D 612 |
| Chain | Residue |
| C | GLY115 |
| C | ASN117 |
| D | SER288 |
| D | LEU289 |
| D | LEU295 |
| D | EDO611 |
| D | HOH706 |
| D | HOH709 |
| site_id | AI7 |
| Number of Residues | 30 |
| Details | binding site for residue TD6 E 601 |
| Chain | Residue |
| E | ASN390 |
| E | SER391 |
| E | LEU392 |
| E | ARG395 |
| E | ARG413 |
| E | SER416 |
| E | GLY417 |
| E | ILE418 |
| E | ASP419 |
| E | GLY441 |
| E | ASP442 |
| E | LEU443 |
| E | SER444 |
| E | TYR447 |
| E | ASN469 |
| E | GLY471 |
| E | GLY472 |
| E | GLN473 |
| E | ILE474 |
| E | MN602 |
| E | MG603 |
| E | HOH783 |
| E | HOH876 |
| E | HOH906 |
| F | PRO30 |
| F | GLU55 |
| F | THR81 |
| F | ASN117 |
| F | GLN118 |
| F | FMT601 |
| site_id | AI8 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 602 |
| Chain | Residue |
| E | ASP442 |
| E | ASN469 |
| E | GLY471 |
| E | TD6601 |
| E | HOH783 |
| site_id | AI9 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 603 |
| Chain | Residue |
| E | ASP442 |
| E | ASN469 |
| E | GLY471 |
| E | TD6601 |
| E | HOH783 |
| site_id | AJ1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL E 604 |
| Chain | Residue |
| E | HIS49 |
| E | HIS50 |
| E | THR51 |
| E | ARG430 |
| E | LEU454 |
| E | GLN457 |
| E | HOH744 |
| E | HOH789 |
| E | HOH879 |
| site_id | AJ2 |
| Number of Residues | 5 |
| Details | binding site for residue FMT E 605 |
| Chain | Residue |
| E | PRO123 |
| E | GLY124 |
| E | ILE134 |
| E | SER135 |
| E | HIS165 |
| site_id | AJ3 |
| Number of Residues | 4 |
| Details | binding site for residue FMT E 606 |
| Chain | Residue |
| E | PRO173 |
| E | LEU174 |
| E | TYR175 |
| E | HOH853 |
| site_id | AJ4 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 607 |
| Chain | Residue |
| E | ASP311 |
| E | HOH716 |
| E | HOH742 |
| E | HOH851 |
| E | HOH925 |
| E | HOH933 |
| site_id | AJ5 |
| Number of Residues | 4 |
| Details | binding site for residue FMT E 608 |
| Chain | Residue |
| E | LYS70 |
| E | HOH716 |
| E | HOH733 |
| E | HOH734 |
| site_id | AJ6 |
| Number of Residues | 7 |
| Details | binding site for residue FMT E 609 |
| Chain | Residue |
| E | ARG121 |
| E | PRO123 |
| E | MET125 |
| E | HOH703 |
| F | ALA127 |
| F | SER128 |
| F | HIS129 |
| site_id | AJ7 |
| Number of Residues | 8 |
| Details | binding site for residue FMT E 610 |
| Chain | Residue |
| E | SER288 |
| E | LEU289 |
| E | LEU295 |
| E | HOH701 |
| E | HOH710 |
| E | HOH844 |
| F | GLY115 |
| F | ASN117 |
| site_id | AJ8 |
| Number of Residues | 3 |
| Details | binding site for residue FMT E 611 |
| Chain | Residue |
| E | HIS25 |
| E | ALA431 |
| E | HOH1061 |
| site_id | AJ9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 612 |
| Chain | Residue |
| E | HOH728 |
| E | HOH878 |
| E | HOH1070 |
| site_id | AK1 |
| Number of Residues | 8 |
| Details | binding site for residue FMT E 613 |
| Chain | Residue |
| E | GLY31 |
| E | SER32 |
| E | ARG33 |
| E | THR78 |
| E | ARG107 |
| E | GLN118 |
| E | HOH1054 |
| F | TD6602 |
| site_id | AK2 |
| Number of Residues | 8 |
| Details | binding site for residue FMT F 601 |
| Chain | Residue |
| E | TD6601 |
| F | GLY31 |
| F | SER32 |
| F | ARG33 |
| F | THR78 |
| F | ARG107 |
| F | GLN118 |
| F | HOH1045 |
| site_id | AK3 |
| Number of Residues | 31 |
| Details | binding site for residue TD6 F 602 |
| Chain | Residue |
| E | PRO30 |
| E | GLU55 |
| E | THR81 |
| E | ALA82 |
| E | ASN117 |
| E | GLN118 |
| E | FMT613 |
| F | ASN390 |
| F | SER391 |
| F | LEU392 |
| F | ARG395 |
| F | ARG413 |
| F | SER416 |
| F | GLY417 |
| F | ILE418 |
| F | ASP419 |
| F | GLY441 |
| F | ASP442 |
| F | LEU443 |
| F | SER444 |
| F | TYR447 |
| F | ASN469 |
| F | GLY471 |
| F | GLY472 |
| F | GLN473 |
| F | ILE474 |
| F | MN603 |
| F | MG604 |
| F | HOH757 |
| F | HOH820 |
| F | HOH921 |
| site_id | AK4 |
| Number of Residues | 5 |
| Details | binding site for residue MN F 603 |
| Chain | Residue |
| F | ASP442 |
| F | ASN469 |
| F | GLY471 |
| F | TD6602 |
| F | HOH820 |
| site_id | AK5 |
| Number of Residues | 5 |
| Details | binding site for residue MG F 604 |
| Chain | Residue |
| F | ASP442 |
| F | ASN469 |
| F | GLY471 |
| F | TD6602 |
| F | HOH820 |
| site_id | AK6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL F 605 |
| Chain | Residue |
| F | HIS49 |
| F | HIS50 |
| F | THR51 |
| F | ARG430 |
| F | LEU454 |
| F | GLN457 |
| F | HOH748 |
| F | HOH755 |
| F | HOH926 |
| site_id | AK7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL F 606 |
| Chain | Residue |
| F | ARG364 |
| F | HIS374 |
| F | ARG375 |
| F | ASP378 |
| F | HOH1193 |
| site_id | AK8 |
| Number of Residues | 4 |
| Details | binding site for residue FMT F 607 |
| Chain | Residue |
| F | PRO198 |
| F | ARG201 |
| F | HOH731 |
| F | HOH913 |
| site_id | AK9 |
| Number of Residues | 5 |
| Details | binding site for residue FMT F 608 |
| Chain | Residue |
| F | GLN242 |
| F | TRP246 |
| F | HOH853 |
| F | HOH870 |
| F | HOH875 |
| site_id | AL1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO F 609 |
| Chain | Residue |
| F | HOH723 |
| F | HOH1206 |
| site_id | AL2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO F 610 |
| Chain | Residue |
| E | ARG487 |
| F | HIS49 |
| F | HOH743 |
| site_id | AL3 |
| Number of Residues | 9 |
| Details | binding site for residue FMT F 611 |
| Chain | Residue |
| E | GLY115 |
| F | SER288 |
| F | LEU289 |
| F | LEU295 |
| F | HOH705 |
| F | HOH717 |
| F | HOH720 |
| F | HOH747 |
| F | HOH844 |
| site_id | AL4 |
| Number of Residues | 30 |
| Details | binding site for residue TD6 G 601 |
| Chain | Residue |
| G | ASN390 |
| G | SER391 |
| G | LEU392 |
| G | ARG395 |
| G | ARG413 |
| G | SER416 |
| G | GLY417 |
| G | ILE418 |
| G | ASP419 |
| G | GLY441 |
| G | ASP442 |
| G | LEU443 |
| G | SER444 |
| G | ASN469 |
| G | GLY471 |
| G | GLY472 |
| G | GLN473 |
| G | ILE474 |
| G | MN602 |
| G | MG603 |
| G | HOH817 |
| G | HOH818 |
| G | HOH941 |
| H | PRO30 |
| H | GLU55 |
| H | THR81 |
| H | ALA82 |
| H | ASN117 |
| H | GLN118 |
| H | FMT601 |
| site_id | AL5 |
| Number of Residues | 5 |
| Details | binding site for residue MN G 602 |
| Chain | Residue |
| G | ASP442 |
| G | ASN469 |
| G | GLY471 |
| G | TD6601 |
| G | HOH818 |
| site_id | AL6 |
| Number of Residues | 5 |
| Details | binding site for residue MG G 603 |
| Chain | Residue |
| G | ASP442 |
| G | ASN469 |
| G | GLY471 |
| G | TD6601 |
| G | HOH818 |
| site_id | AL7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL G 604 |
| Chain | Residue |
| G | HIS49 |
| G | HIS50 |
| G | THR51 |
| G | ARG430 |
| G | LEU454 |
| G | HOH711 |
| G | HOH739 |
| G | HOH775 |
| site_id | AL8 |
| Number of Residues | 5 |
| Details | binding site for residue MG G 605 |
| Chain | Residue |
| G | ASP311 |
| G | HOH805 |
| G | HOH1003 |
| G | HOH1092 |
| G | HOH1246 |
| site_id | AL9 |
| Number of Residues | 7 |
| Details | binding site for residue FMT G 606 |
| Chain | Residue |
| G | ARG24 |
| G | HIS25 |
| G | SER69 |
| G | GLN71 |
| G | HOH788 |
| G | HOH1029 |
| G | HOH1031 |
| site_id | AM1 |
| Number of Residues | 5 |
| Details | binding site for residue FMT G 607 |
| Chain | Residue |
| G | PRO173 |
| G | LEU174 |
| G | TYR175 |
| G | HOH725 |
| G | HOH863 |
| site_id | AM2 |
| Number of Residues | 4 |
| Details | binding site for residue FMT G 608 |
| Chain | Residue |
| G | ARG430 |
| G | GLN457 |
| G | HOH838 |
| G | HOH857 |
| site_id | AM3 |
| Number of Residues | 3 |
| Details | binding site for residue FMT G 609 |
| Chain | Residue |
| G | GLN186 |
| G | TRP193 |
| G | HOH702 |
| site_id | AM4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO G 610 |
| Chain | Residue |
| G | ARG364 |
| G | HIS374 |
| G | ASP378 |
| G | FMT611 |
| site_id | AM5 |
| Number of Residues | 5 |
| Details | binding site for residue FMT G 611 |
| Chain | Residue |
| D | HOH1226 |
| G | ARG364 |
| G | EDO610 |
| G | HOH1026 |
| G | HOH1111 |
| site_id | AM6 |
| Number of Residues | 5 |
| Details | binding site for residue FMT G 612 |
| Chain | Residue |
| G | HIS374 |
| G | CYS377 |
| G | SER401 |
| G | GLN402 |
| G | HOH707 |
| site_id | AM7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 613 |
| Chain | Residue |
| G | LEU295 |
| G | HOH905 |
| G | HOH1141 |
| site_id | AM8 |
| Number of Residues | 7 |
| Details | binding site for residue FMT G 614 |
| Chain | Residue |
| G | SER288 |
| G | LEU289 |
| G | LEU295 |
| G | HOH703 |
| G | HOH726 |
| G | HOH773 |
| H | GLY115 |
| site_id | AM9 |
| Number of Residues | 8 |
| Details | binding site for residue FMT G 615 |
| Chain | Residue |
| G | GLY31 |
| G | SER32 |
| G | ARG33 |
| G | THR78 |
| G | ARG107 |
| G | GLN118 |
| G | HOH950 |
| H | TD6602 |
| site_id | AN1 |
| Number of Residues | 8 |
| Details | binding site for residue FMT H 601 |
| Chain | Residue |
| G | TD6601 |
| H | GLY31 |
| H | SER32 |
| H | ARG33 |
| H | THR78 |
| H | ARG107 |
| H | GLN118 |
| H | HOH1051 |
| site_id | AN2 |
| Number of Residues | 30 |
| Details | binding site for residue TD6 H 602 |
| Chain | Residue |
| G | PRO30 |
| G | GLU55 |
| G | THR81 |
| G | ALA82 |
| G | ASN117 |
| G | GLN118 |
| G | FMT615 |
| H | ASN390 |
| H | SER391 |
| H | LEU392 |
| H | ARG395 |
| H | ARG413 |
| H | SER416 |
| H | GLY417 |
| H | ILE418 |
| H | ASP419 |
| H | GLY441 |
| H | ASP442 |
| H | LEU443 |
| H | SER444 |
| H | ASN469 |
| H | GLY471 |
| H | GLY472 |
| H | GLN473 |
| H | ILE474 |
| H | MN603 |
| H | MG604 |
| H | HOH802 |
| H | HOH830 |
| H | HOH941 |
| site_id | AN3 |
| Number of Residues | 5 |
| Details | binding site for residue MN H 603 |
| Chain | Residue |
| H | ASP442 |
| H | ASN469 |
| H | GLY471 |
| H | TD6602 |
| H | HOH830 |
| site_id | AN4 |
| Number of Residues | 5 |
| Details | binding site for residue MG H 604 |
| Chain | Residue |
| H | ASP442 |
| H | ASN469 |
| H | GLY471 |
| H | TD6602 |
| H | HOH830 |
| site_id | AN5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL H 605 |
| Chain | Residue |
| H | HIS49 |
| H | HIS50 |
| H | THR51 |
| H | ARG430 |
| H | LEU454 |
| H | GLN457 |
| H | HOH764 |
| H | HOH768 |
| H | HOH848 |
| site_id | AN6 |
| Number of Residues | 4 |
| Details | binding site for residue FMT H 606 |
| Chain | Residue |
| G | ARG487 |
| H | ILE48 |
| H | HIS49 |
| H | HOH1105 |
| site_id | AN7 |
| Number of Residues | 12 |
| Details | binding site for residue GOL H 607 |
| Chain | Residue |
| H | THR96 |
| H | ARG228 |
| H | ASP310 |
| H | ASP311 |
| H | ILE312 |
| H | MG608 |
| H | HOH703 |
| H | HOH780 |
| H | HOH813 |
| H | HOH1035 |
| H | HOH1098 |
| H | HOH1150 |
| site_id | AN8 |
| Number of Residues | 6 |
| Details | binding site for residue MG H 608 |
| Chain | Residue |
| H | ASP311 |
| H | GOL607 |
| H | HOH813 |
| H | HOH1018 |
| H | HOH1098 |
| H | HOH1150 |
| site_id | AN9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO H 609 |
| Chain | Residue |
| G | GLY115 |
| G | ASN117 |
| G | HOH715 |
| H | SER288 |
| H | LEU289 |
| H | LEU295 |
| H | HOH738 |
| H | HOH757 |
| H | HOH843 |
| site_id | AO1 |
| Number of Residues | 4 |
| Details | binding site for residue FMT H 610 |
| Chain | Residue |
| H | LYS292 |
| H | ARG395 |
| H | HOH719 |
| H | HOH883 |
| site_id | AO2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL H 611 |
| Chain | Residue |
| E | GLN219 |
| E | ARG342 |
| E | HOH1085 |
| H | GLY433 |
| H | SER459 |
| H | ALA460 |
| H | HOH721 |
| site_id | AO3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO H 612 |
| Chain | Residue |
| H | ARG364 |
| H | HIS374 |
| H | ASP378 |
| H | HOH1095 |
| site_id | AO4 |
| Number of Residues | 5 |
| Details | binding site for residue FMT H 613 |
| Chain | Residue |
| H | HOH790 |
| H | HOH958 |
| H | HOH1023 |
| H | HOH1080 |
| H | HOH1129 |
