5EE5
Structure of human ARL1 in complex with the DCB domain of BIG1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005802 | cellular_component | trans-Golgi network |
| B | 0005829 | cellular_component | cytosol |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0007030 | biological_process | Golgi organization |
| B | 0008047 | molecular_function | enzyme activator activity |
| B | 0009404 | biological_process | toxin metabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0019904 | molecular_function | protein domain specific binding |
| B | 0032588 | cellular_component | trans-Golgi network membrane |
| B | 0034067 | biological_process | protein localization to Golgi apparatus |
| B | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1990583 | molecular_function | phospholipase D activator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | ASN187 |
| A | ASN190 |
| B | GLN64 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 304 |
| Chain | Residue |
| A | GLU47 |
| A | GLN51 |
| A | HOH408 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | TYR182 |
| A | GLN191 |
| A | CL313 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 308 |
| Chain | Residue |
| A | ARG176 |
| A | ASN180 |
| A | LEU202 |
| A | ASN203 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 312 |
| Chain | Residue |
| A | LEU100 |
| A | ASP101 |
| A | GLN104 |
| A | GLN150 |
| A | LYS153 |
| A | ALA154 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 313 |
| Chain | Residue |
| A | GOL307 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | binding site for residue GTP B 201 |
| Chain | Residue |
| B | ASP26 |
| B | GLY27 |
| B | ALA28 |
| B | GLY29 |
| B | LYS30 |
| B | THR31 |
| B | THR32 |
| B | THR45 |
| B | THR48 |
| B | GLY69 |
| B | GLY70 |
| B | ASN126 |
| B | LYS127 |
| B | ASP129 |
| B | MET130 |
| B | SER159 |
| B | ALA160 |
| B | THR161 |
| B | MG202 |
| B | MG205 |
| B | HOH305 |
| B | HOH308 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 202 |
| Chain | Residue |
| B | THR31 |
| B | THR48 |
| B | ASP67 |
| B | GTP201 |
| B | MG205 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 203 |
| Chain | Residue |
| B | ASP93 |
| B | ASP96 |
| B | ARG99 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 204 |
| Chain | Residue |
| B | THR57 |
| B | TYR58 |
| B | LEU61 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 205 |
| Chain | Residue |
| B | THR31 |
| B | ILE46 |
| B | THR48 |
| B | GTP201 |
| B | MG202 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 206 |
| Chain | Residue |
| B | GLU112 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 207 |
| Chain | Residue |
| B | ASP150 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 208 |
| Chain | Residue |
| B | VAL39 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 212 |
| Chain | Residue |
| B | CYS95 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 213 |
| Chain | Residue |
| B | GLU171 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 214 |
| Chain | Residue |
| B | ARG75 |
| B | PRO76 |
| B | GLU106 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 215 |
| Chain | Residue |
| B | ALA119 |
| B | LYS152 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue ACT B 216 |
| Chain | Residue |
| B | TYR77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14580338","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27373159","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27436755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14580338","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
