5EC1

KcsA with V76ester mutation

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue F09 C 2001

Chain	Residue
A	ARG57
C	LEU46
C	LEU90
C	VAL91
C	VAL94

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site_id	AC2
Number of Residues	7
Details	binding site for residue DGA C 2002

Chain	Residue
C	CYS70
C	LEU86
C	ARG89
C	SER44
C	TYR45
C	PRO63
C	LEU66

---

site_id	AC3
Number of Residues	8
Details	binding site for residue K C 2003

Chain	Residue
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78

---

site_id	AC4
Number of Residues	8
Details	binding site for residue K C 2004

Chain	Residue
C	LHV76
C	LHV76
C	LHV76
C	LHV76
C	GLY77
C	GLY77
C	GLY77
C	GLY77

---

site_id	AC5
Number of Residues	4
Details	binding site for residue K C 2005

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75

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site_id	AC6
Number of Residues	4
Details	binding site for residue K C 2007

Chain	Residue
C	K2008
C	K2008
C	K2008
C	K2008

---

site_id	AC7
Number of Residues	4
Details	binding site for residue K C 2008

Chain	Residue
C	K2007
C	K2007
C	K2007
C	K2007

---

site_id	AC8
Number of Residues	14
Details	binding site for Ligand residues LHV C 76 through GLY C 77 bound to THR C 75

Chain	Residue
C	GLU71
C	THR74
C	THR75
C	THR75
C	TYR78
C	GLY79
C	K2003
C	K2003
C	K2003
C	K2003
C	K2004
C	K2004
C	K2004
C	K2004

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

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