5EAN

Crystal structure of Dna2 in complex with a 5' overhang DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000076	biological_process	DNA replication checkpoint signaling
A	0000166	molecular_function	nucleotide binding
A	0000723	biological_process	telomere maintenance
A	0000729	biological_process	DNA double-strand break processing
A	0000781	cellular_component	chromosome, telomeric region
A	0003677	molecular_function	DNA binding
A	0003678	molecular_function	DNA helicase activity
A	0003723	molecular_function	RNA binding
A	0003824	molecular_function	catalytic activity
A	0004386	molecular_function	helicase activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005760	cellular_component	gamma DNA polymerase complex
A	0006260	biological_process	DNA replication
A	0006264	biological_process	mitochondrial DNA replication
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006974	biological_process	DNA damage response
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0016890	molecular_function	obsolete site-specific endodeoxyribonuclease activity, specific for altered base
A	0017108	molecular_function	5'-flap endonuclease activity
A	0017116	molecular_function	single-stranded DNA helicase activity
A	0032201	biological_process	telomere maintenance via semi-conservative replication
A	0033567	biological_process	DNA replication, Okazaki fragment processing
A	0033892	molecular_function	deoxyribonuclease (pyrimidine dimer) activity
A	0042645	cellular_component	mitochondrial nucleoid
A	0043137	biological_process	DNA replication, removal of RNA primer
A	0043139	molecular_function	5'-3' DNA helicase activity
A	0043504	biological_process	mitochondrial DNA repair
A	0045740	biological_process	positive regulation of DNA replication
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0071932	biological_process	replication fork reversal
A	1902990	biological_process	mitotic telomere maintenance via semi-conservative replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SF4 A 1101

Chain	Residue
A	CYS137
A	ARG140
A	CYS394
A	CYS397
A	CYS403

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site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 1102

Chain	Residue
B	DA12
B	HOH201
A	HIS164
A	ASP278
A	GLU299
A	LEU300

---

site_id	AC3
Number of Residues	9
Details	binding site for residue ADP A 1103

Chain	Residue
A	GLY626
A	LEU627
A	ASN628
A	GLN631
A	GLY654
A	THR656
A	THR657
A	LYS689
A	TYR828

---

site_id	AC4
Number of Residues	7
Details	binding site for residue CA B 101

Chain	Residue
A	LYS301
A	HOH1202
B	DG11
B	DA12
B	DG13
B	HOH201
B	HOH202

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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