5E9C
Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
| Chain | Residue | Details |
| B | ASP62 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B |
| Chain | Residue | Details |
| B | THR97 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15760902 |
| Chain | Residue | Details |
| A | LYS158 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15760902, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E9C |
| Chain | Residue | Details |
| A | GLN270 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E9C |
| Chain | Residue | Details |
| A | ARG303 | |
| A | HIS296 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B |
| Chain | Residue | Details |
| A | TYR348 | |
| A | GLY389 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97 |
| Chain | Residue | Details |
| A | ASN162 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609 |
| Chain | Residue | Details |
| A | ASN178 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
| Chain | Residue | Details |
| A | ASN200 | |
| A | ASN459 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M |
| Chain | Residue | Details |
| A | ASN217 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14573609, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:28581485, ECO:0007744|PDB:5E8M, ECO:0007744|PDB:5E97, ECO:0007744|PDB:5E98, ECO:0007744|PDB:5E9B, ECO:0007744|PDB:5E9C |
| Chain | Residue | Details |
| A | ASN238 |
