Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0015035 | molecular_function | protein-disulfide reductase activity |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 201 |
| Chain | Residue |
| B | PRO74 |
| B | GLY75 |
| B | GLY107 |
| B | GLU111 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 401 |
| Chain | Residue |
| C | HOH514 |
| C | GLU268 |
| C | GLU323 |
| C | HOH507 |
| C | HOH508 |
| C | HOH513 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 401 |
| Chain | Residue |
| D | TYR269 |
| D | ALA270 |
| D | VAL272 |
| D | ALA306 |
| D | ASP308 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| A | HOH202 |
| D | GLU268 |
| D | HOH503 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL |
| Chain | Residue | Details |
| A | LEU34-LEU52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Deprotonates C-terminal active site Cys","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Contributes to redox potential value","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 100 |
| Details | Domain: {"description":"Chromo 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00053","evidenceCode":"ECO:0000255"}]} |
