5E38

Structural basis of mapping the spontaneous mutations with 5-flourouracil in uracil phosphoribosyltransferase from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004845	molecular_function	uracil phosphoribosyltransferase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006223	biological_process	uracil salvage
A	0008655	biological_process	pyrimidine-containing compound salvage
A	0016757	molecular_function	glycosyltransferase activity
A	0044206	biological_process	UMP salvage
B	0000287	molecular_function	magnesium ion binding
B	0004845	molecular_function	uracil phosphoribosyltransferase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0006223	biological_process	uracil salvage
B	0008655	biological_process	pyrimidine-containing compound salvage
B	0016757	molecular_function	glycosyltransferase activity
B	0044206	biological_process	UMP salvage
C	0000287	molecular_function	magnesium ion binding
C	0004845	molecular_function	uracil phosphoribosyltransferase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0006223	biological_process	uracil salvage
C	0008655	biological_process	pyrimidine-containing compound salvage
C	0016757	molecular_function	glycosyltransferase activity
C	0044206	biological_process	UMP salvage
D	0000287	molecular_function	magnesium ion binding
D	0004845	molecular_function	uracil phosphoribosyltransferase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0006223	biological_process	uracil salvage
D	0008655	biological_process	pyrimidine-containing compound salvage
D	0016757	molecular_function	glycosyltransferase activity
D	0044206	biological_process	UMP salvage

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01218

Chain	Residue	Details
A	ARG77
B	ILE192
B	GLY197
B	ASP198
C	ARG77
C	ARG102
C	ASP129
C	ILE192
C	GLY197
C	ASP198
D	ARG77
A	ARG102
D	ARG102
D	ASP129
D	ILE192
D	GLY197
D	ASP198
A	ASP129
A	ILE192
A	GLY197
A	ASP198
B	ARG77
B	ARG102
B	ASP129

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