5E1A

Structure of KcsA with L24C/R117C mutations

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue K C 3001

Chain	Residue
C	GLY77
C	K3002
C	K3002
C	K3002
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K3002

---

site_id	AC2
Number of Residues	16
Details	binding site for residue K C 3002

Chain	Residue
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	K3001
C	K3001
C	K3001
C	K3001
C	K3003
C	K3003
C	K3003
C	K3003

---

site_id	AC3
Number of Residues	16
Details	binding site for residue K C 3003

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	K3002
C	K3002
C	K3002
C	K3002
C	K3004
C	K3004
C	K3004
C	K3004

---

site_id	AC4
Number of Residues	8
Details	binding site for residue K C 3004

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K3003
C	K3003
C	K3003
C	K3003

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	7
Details	Intramembrane: {"description":"Pore-forming"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	5
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

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