5E0O

Brugia malayi Trehalose-6 Phosphate Phosphatase in complex with PEG at the active site.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004805	molecular_function	trehalose-phosphatase activity
A	0005737	cellular_component	cytoplasm
A	0005992	biological_process	trehalose biosynthetic process
A	0016311	biological_process	dephosphorylation
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	1901136	biological_process	carbohydrate derivative catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MG A 501

Chain	Residue
A	ASP213
A	ASP215
A	ASP424
A	THR425
A	ASP428
A	PEG503
A	HOH602

---

site_id	AC2
Number of Residues	7
Details	binding site for residue SO4 A 502

Chain	Residue
A	SER427
A	LYS451
A	SER453
A	PEG503
A	HOH618
A	THR425
A	LEU426

---

site_id	AC3
Number of Residues	11
Details	binding site for residue PEG A 503

Chain	Residue
A	ASP213
A	TRP214
A	ASP215
A	ALA254
A	TRP280
A	LYS398
A	THR425
A	SER427
A	MG501
A	SO4502
A	HOH602

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"24992307","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24992307","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"24992307","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---