5DY7
Crystal structure of the human BRPF1 bromodomain in complex with SEED4
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 5GT A 801 |
| Chain | Residue |
| A | ILE652 |
| A | VAL657 |
| A | PRO658 |
| A | GLU661 |
| A | VAL662 |
| A | ASN708 |
| A | PHE714 |
| A | HOH917 |
| A | HOH929 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 802 |
| Chain | Residue |
| A | SER702 |
| A | LEU705 |
| A | LYS706 |
| A | TYR715 |
| A | VAL719 |
| A | ARG722 |
| A | HOH915 |
| A | HOH987 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
