5DSV

Crystal structure of human proteasome alpha7 tetradecamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005839	cellular_component	proteasome core complex
A	0006281	biological_process	DNA repair
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0006915	biological_process	apoptotic process
A	0006974	biological_process	DNA damage response
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0008021	cellular_component	synaptic vesicle
A	0010498	biological_process	proteasomal protein catabolic process
A	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0030317	biological_process	flagellated sperm motility
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032729	biological_process	positive regulation of type II interferon production
A	0032743	biological_process	positive regulation of interleukin-2 production
A	0032760	biological_process	positive regulation of tumor necrosis factor production
A	0034341	biological_process	response to type II interferon
A	0034515	cellular_component	proteasome storage granule
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
A	0045061	biological_process	thymic T cell selection
A	0045063	biological_process	T-helper 1 cell differentiation
A	0045590	biological_process	negative regulation of regulatory T cell differentiation
A	0051321	biological_process	meiotic cell cycle
A	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	0070062	cellular_component	extracellular exosome
A	0071357	biological_process	cellular response to type I interferon
A	0072539	biological_process	T-helper 17 cell differentiation
A	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
A	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
B	0000502	cellular_component	proteasome complex
B	0002376	biological_process	immune system process
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005839	cellular_component	proteasome core complex
B	0006281	biological_process	DNA repair
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0006915	biological_process	apoptotic process
B	0006974	biological_process	DNA damage response
B	0006979	biological_process	response to oxidative stress
B	0007283	biological_process	spermatogenesis
B	0008021	cellular_component	synaptic vesicle
B	0010498	biological_process	proteasomal protein catabolic process
B	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0030317	biological_process	flagellated sperm motility
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032729	biological_process	positive regulation of type II interferon production
B	0032743	biological_process	positive regulation of interleukin-2 production
B	0032760	biological_process	positive regulation of tumor necrosis factor production
B	0034341	biological_process	response to type II interferon
B	0034515	cellular_component	proteasome storage granule
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
B	0045061	biological_process	thymic T cell selection
B	0045063	biological_process	T-helper 1 cell differentiation
B	0045590	biological_process	negative regulation of regulatory T cell differentiation
B	0051321	biological_process	meiotic cell cycle
B	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
B	0061136	biological_process	regulation of proteasomal protein catabolic process
B	0070062	cellular_component	extracellular exosome
B	0071357	biological_process	cellular response to type I interferon
B	0072539	biological_process	T-helper 17 cell differentiation
B	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
B	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
C	0000502	cellular_component	proteasome complex
C	0002376	biological_process	immune system process
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005839	cellular_component	proteasome core complex
C	0006281	biological_process	DNA repair
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0006915	biological_process	apoptotic process
C	0006974	biological_process	DNA damage response
C	0006979	biological_process	response to oxidative stress
C	0007283	biological_process	spermatogenesis
C	0008021	cellular_component	synaptic vesicle
C	0010498	biological_process	proteasomal protein catabolic process
C	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0030317	biological_process	flagellated sperm motility
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032729	biological_process	positive regulation of type II interferon production
C	0032743	biological_process	positive regulation of interleukin-2 production
C	0032760	biological_process	positive regulation of tumor necrosis factor production
C	0034341	biological_process	response to type II interferon
C	0034515	cellular_component	proteasome storage granule
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
C	0045061	biological_process	thymic T cell selection
C	0045063	biological_process	T-helper 1 cell differentiation
C	0045590	biological_process	negative regulation of regulatory T cell differentiation
C	0051321	biological_process	meiotic cell cycle
C	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
C	0061136	biological_process	regulation of proteasomal protein catabolic process
C	0070062	cellular_component	extracellular exosome
C	0071357	biological_process	cellular response to type I interferon
C	0072539	biological_process	T-helper 17 cell differentiation
C	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
C	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
D	0000502	cellular_component	proteasome complex
D	0002376	biological_process	immune system process
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005839	cellular_component	proteasome core complex
D	0006281	biological_process	DNA repair
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0006979	biological_process	response to oxidative stress
D	0007283	biological_process	spermatogenesis
D	0008021	cellular_component	synaptic vesicle
D	0010498	biological_process	proteasomal protein catabolic process
D	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0030317	biological_process	flagellated sperm motility
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0032729	biological_process	positive regulation of type II interferon production
D	0032743	biological_process	positive regulation of interleukin-2 production
D	0032760	biological_process	positive regulation of tumor necrosis factor production
D	0034341	biological_process	response to type II interferon
D	0034515	cellular_component	proteasome storage granule
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
D	0045061	biological_process	thymic T cell selection
D	0045063	biological_process	T-helper 1 cell differentiation
D	0045590	biological_process	negative regulation of regulatory T cell differentiation
D	0051321	biological_process	meiotic cell cycle
D	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
D	0061136	biological_process	regulation of proteasomal protein catabolic process
D	0070062	cellular_component	extracellular exosome
D	0071357	biological_process	cellular response to type I interferon
D	0072539	biological_process	T-helper 17 cell differentiation
D	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
D	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
E	0000502	cellular_component	proteasome complex
E	0002376	biological_process	immune system process
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005839	cellular_component	proteasome core complex
E	0006281	biological_process	DNA repair
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0006915	biological_process	apoptotic process
E	0006974	biological_process	DNA damage response
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0008021	cellular_component	synaptic vesicle
E	0010498	biological_process	proteasomal protein catabolic process
E	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0030317	biological_process	flagellated sperm motility
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032729	biological_process	positive regulation of type II interferon production
E	0032743	biological_process	positive regulation of interleukin-2 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0034341	biological_process	response to type II interferon
E	0034515	cellular_component	proteasome storage granule
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
E	0045061	biological_process	thymic T cell selection
E	0045063	biological_process	T-helper 1 cell differentiation
E	0045590	biological_process	negative regulation of regulatory T cell differentiation
E	0051321	biological_process	meiotic cell cycle
E	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
E	0061136	biological_process	regulation of proteasomal protein catabolic process
E	0070062	cellular_component	extracellular exosome
E	0071357	biological_process	cellular response to type I interferon
E	0072539	biological_process	T-helper 17 cell differentiation
E	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
E	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
F	0000502	cellular_component	proteasome complex
F	0002376	biological_process	immune system process
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006281	biological_process	DNA repair
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0006915	biological_process	apoptotic process
F	0006974	biological_process	DNA damage response
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0008021	cellular_component	synaptic vesicle
F	0010498	biological_process	proteasomal protein catabolic process
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0030317	biological_process	flagellated sperm motility
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032729	biological_process	positive regulation of type II interferon production
F	0032743	biological_process	positive regulation of interleukin-2 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0034341	biological_process	response to type II interferon
F	0034515	cellular_component	proteasome storage granule
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
F	0045061	biological_process	thymic T cell selection
F	0045063	biological_process	T-helper 1 cell differentiation
F	0045590	biological_process	negative regulation of regulatory T cell differentiation
F	0051321	biological_process	meiotic cell cycle
F	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0070062	cellular_component	extracellular exosome
F	0071357	biological_process	cellular response to type I interferon
F	0072539	biological_process	T-helper 17 cell differentiation
F	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
F	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	0000502	cellular_component	proteasome complex
G	0002376	biological_process	immune system process
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0006281	biological_process	DNA repair
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006915	biological_process	apoptotic process
G	0006974	biological_process	DNA damage response
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0008021	cellular_component	synaptic vesicle
G	0010498	biological_process	proteasomal protein catabolic process
G	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030317	biological_process	flagellated sperm motility
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032729	biological_process	positive regulation of type II interferon production
G	0032743	biological_process	positive regulation of interleukin-2 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0034341	biological_process	response to type II interferon
G	0034515	cellular_component	proteasome storage granule
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
G	0045061	biological_process	thymic T cell selection
G	0045063	biological_process	T-helper 1 cell differentiation
G	0045590	biological_process	negative regulation of regulatory T cell differentiation
G	0051321	biological_process	meiotic cell cycle
G	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0070062	cellular_component	extracellular exosome
G	0071357	biological_process	cellular response to type I interferon
G	0072539	biological_process	T-helper 17 cell differentiation
G	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
H	0000502	cellular_component	proteasome complex
H	0002376	biological_process	immune system process
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005839	cellular_component	proteasome core complex
H	0006281	biological_process	DNA repair
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
H	0006915	biological_process	apoptotic process
H	0006974	biological_process	DNA damage response
H	0006979	biological_process	response to oxidative stress
H	0007283	biological_process	spermatogenesis
H	0008021	cellular_component	synaptic vesicle
H	0010498	biological_process	proteasomal protein catabolic process
H	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
H	0019773	cellular_component	proteasome core complex, alpha-subunit complex
H	0030317	biological_process	flagellated sperm motility
H	0031625	molecular_function	ubiquitin protein ligase binding
H	0032729	biological_process	positive regulation of type II interferon production
H	0032743	biological_process	positive regulation of interleukin-2 production
H	0032760	biological_process	positive regulation of tumor necrosis factor production
H	0034341	biological_process	response to type II interferon
H	0034515	cellular_component	proteasome storage granule
H	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
H	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
H	0045061	biological_process	thymic T cell selection
H	0045063	biological_process	T-helper 1 cell differentiation
H	0045590	biological_process	negative regulation of regulatory T cell differentiation
H	0051321	biological_process	meiotic cell cycle
H	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
H	0061136	biological_process	regulation of proteasomal protein catabolic process
H	0070062	cellular_component	extracellular exosome
H	0071357	biological_process	cellular response to type I interferon
H	0072539	biological_process	T-helper 17 cell differentiation
H	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000502	cellular_component	proteasome complex
I	0002376	biological_process	immune system process
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005839	cellular_component	proteasome core complex
I	0006281	biological_process	DNA repair
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0006915	biological_process	apoptotic process
I	0006974	biological_process	DNA damage response
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0008021	cellular_component	synaptic vesicle
I	0010498	biological_process	proteasomal protein catabolic process
I	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
I	0019773	cellular_component	proteasome core complex, alpha-subunit complex
I	0030317	biological_process	flagellated sperm motility
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032729	biological_process	positive regulation of type II interferon production
I	0032743	biological_process	positive regulation of interleukin-2 production
I	0032760	biological_process	positive regulation of tumor necrosis factor production
I	0034341	biological_process	response to type II interferon
I	0034515	cellular_component	proteasome storage granule
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
I	0045061	biological_process	thymic T cell selection
I	0045063	biological_process	T-helper 1 cell differentiation
I	0045590	biological_process	negative regulation of regulatory T cell differentiation
I	0051321	biological_process	meiotic cell cycle
I	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
I	0061136	biological_process	regulation of proteasomal protein catabolic process
I	0070062	cellular_component	extracellular exosome
I	0071357	biological_process	cellular response to type I interferon
I	0072539	biological_process	T-helper 17 cell differentiation
I	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
J	0000502	cellular_component	proteasome complex
J	0002376	biological_process	immune system process
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005839	cellular_component	proteasome core complex
J	0006281	biological_process	DNA repair
J	0006511	biological_process	ubiquitin-dependent protein catabolic process
J	0006915	biological_process	apoptotic process
J	0006974	biological_process	DNA damage response
J	0006979	biological_process	response to oxidative stress
J	0007283	biological_process	spermatogenesis
J	0008021	cellular_component	synaptic vesicle
J	0010498	biological_process	proteasomal protein catabolic process
J	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
J	0019773	cellular_component	proteasome core complex, alpha-subunit complex
J	0030317	biological_process	flagellated sperm motility
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032729	biological_process	positive regulation of type II interferon production
J	0032743	biological_process	positive regulation of interleukin-2 production
J	0032760	biological_process	positive regulation of tumor necrosis factor production
J	0034341	biological_process	response to type II interferon
J	0034515	cellular_component	proteasome storage granule
J	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
J	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
J	0045061	biological_process	thymic T cell selection
J	0045063	biological_process	T-helper 1 cell differentiation
J	0045590	biological_process	negative regulation of regulatory T cell differentiation
J	0051321	biological_process	meiotic cell cycle
J	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
J	0061136	biological_process	regulation of proteasomal protein catabolic process
J	0070062	cellular_component	extracellular exosome
J	0071357	biological_process	cellular response to type I interferon
J	0072539	biological_process	T-helper 17 cell differentiation
J	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
K	0000502	cellular_component	proteasome complex
K	0002376	biological_process	immune system process
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005839	cellular_component	proteasome core complex
K	0006281	biological_process	DNA repair
K	0006511	biological_process	ubiquitin-dependent protein catabolic process
K	0006915	biological_process	apoptotic process
K	0006974	biological_process	DNA damage response
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0008021	cellular_component	synaptic vesicle
K	0010498	biological_process	proteasomal protein catabolic process
K	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
K	0019773	cellular_component	proteasome core complex, alpha-subunit complex
K	0030317	biological_process	flagellated sperm motility
K	0031625	molecular_function	ubiquitin protein ligase binding
K	0032729	biological_process	positive regulation of type II interferon production
K	0032743	biological_process	positive regulation of interleukin-2 production
K	0032760	biological_process	positive regulation of tumor necrosis factor production
K	0034341	biological_process	response to type II interferon
K	0034515	cellular_component	proteasome storage granule
K	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
K	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
K	0045061	biological_process	thymic T cell selection
K	0045063	biological_process	T-helper 1 cell differentiation
K	0045590	biological_process	negative regulation of regulatory T cell differentiation
K	0051321	biological_process	meiotic cell cycle
K	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0070062	cellular_component	extracellular exosome
K	0071357	biological_process	cellular response to type I interferon
K	0072539	biological_process	T-helper 17 cell differentiation
K	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	0000502	cellular_component	proteasome complex
L	0002376	biological_process	immune system process
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005839	cellular_component	proteasome core complex
L	0006281	biological_process	DNA repair
L	0006511	biological_process	ubiquitin-dependent protein catabolic process
L	0006915	biological_process	apoptotic process
L	0006974	biological_process	DNA damage response
L	0006979	biological_process	response to oxidative stress
L	0007283	biological_process	spermatogenesis
L	0008021	cellular_component	synaptic vesicle
L	0010498	biological_process	proteasomal protein catabolic process
L	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
L	0019773	cellular_component	proteasome core complex, alpha-subunit complex
L	0030317	biological_process	flagellated sperm motility
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032729	biological_process	positive regulation of type II interferon production
L	0032743	biological_process	positive regulation of interleukin-2 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0034341	biological_process	response to type II interferon
L	0034515	cellular_component	proteasome storage granule
L	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
L	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
L	0045061	biological_process	thymic T cell selection
L	0045063	biological_process	T-helper 1 cell differentiation
L	0045590	biological_process	negative regulation of regulatory T cell differentiation
L	0051321	biological_process	meiotic cell cycle
L	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	0072539	biological_process	T-helper 17 cell differentiation
L	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	0000502	cellular_component	proteasome complex
M	0002376	biological_process	immune system process
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005839	cellular_component	proteasome core complex
M	0006281	biological_process	DNA repair
M	0006511	biological_process	ubiquitin-dependent protein catabolic process
M	0006915	biological_process	apoptotic process
M	0006974	biological_process	DNA damage response
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0008021	cellular_component	synaptic vesicle
M	0010498	biological_process	proteasomal protein catabolic process
M	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
M	0019773	cellular_component	proteasome core complex, alpha-subunit complex
M	0030317	biological_process	flagellated sperm motility
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032729	biological_process	positive regulation of type II interferon production
M	0032743	biological_process	positive regulation of interleukin-2 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0034341	biological_process	response to type II interferon
M	0034515	cellular_component	proteasome storage granule
M	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
M	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
M	0045061	biological_process	thymic T cell selection
M	0045063	biological_process	T-helper 1 cell differentiation
M	0045590	biological_process	negative regulation of regulatory T cell differentiation
M	0051321	biological_process	meiotic cell cycle
M	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	0072539	biological_process	T-helper 17 cell differentiation
M	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	0000502	cellular_component	proteasome complex
N	0002376	biological_process	immune system process
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005839	cellular_component	proteasome core complex
N	0006281	biological_process	DNA repair
N	0006511	biological_process	ubiquitin-dependent protein catabolic process
N	0006915	biological_process	apoptotic process
N	0006974	biological_process	DNA damage response
N	0006979	biological_process	response to oxidative stress
N	0007283	biological_process	spermatogenesis
N	0008021	cellular_component	synaptic vesicle
N	0010498	biological_process	proteasomal protein catabolic process
N	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
N	0019773	cellular_component	proteasome core complex, alpha-subunit complex
N	0030317	biological_process	flagellated sperm motility
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0032729	biological_process	positive regulation of type II interferon production
N	0032743	biological_process	positive regulation of interleukin-2 production
N	0032760	biological_process	positive regulation of tumor necrosis factor production
N	0034341	biological_process	response to type II interferon
N	0034515	cellular_component	proteasome storage granule
N	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
N	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
N	0045061	biological_process	thymic T cell selection
N	0045063	biological_process	T-helper 1 cell differentiation
N	0045590	biological_process	negative regulation of regulatory T cell differentiation
N	0051321	biological_process	meiotic cell cycle
N	0051603	biological_process	obsolete proteolysis involved in protein catabolic process
N	0061136	biological_process	regulation of proteasomal protein catabolic process
N	0070062	cellular_component	extracellular exosome
N	0071357	biological_process	cellular response to type I interferon
N	0072539	biological_process	T-helper 17 cell differentiation
N	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
N	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsaStFSPdGRvfQVEYAmkA

Chain	Residue	Details
A	TYR7-ALA29

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12376572","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---