5DNY

Structure of the ATPrS-Mre11/Rad50-DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000403	molecular_function	Y-form DNA binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004529	molecular_function	DNA exonuclease activity
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0042802	molecular_function	identical protein binding
A	0045027	molecular_function	DNA end binding
A	0046872	molecular_function	metal ion binding
B	0006302	biological_process	double-strand break repair
B	0016887	molecular_function	ATP hydrolysis activity
C	0000403	molecular_function	Y-form DNA binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004529	molecular_function	DNA exonuclease activity
C	0006281	biological_process	DNA repair
C	0006302	biological_process	double-strand break repair
C	0006974	biological_process	DNA damage response
C	0008408	molecular_function	3'-5' exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0030145	molecular_function	manganese ion binding
C	0042802	molecular_function	identical protein binding
C	0045027	molecular_function	DNA end binding
C	0046872	molecular_function	metal ion binding
D	0006302	biological_process	double-strand break repair
D	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 401

Chain	Residue
A	ASP8
A	HIS10
A	ASP49
A	HIS188
A	MG402

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 402

Chain	Residue
A	MG401
A	ASP49
A	ASN84
A	HIS158
A	HIS186

---

site_id	AC3
Number of Residues	21
Details	binding site for residue AGS B 1101

Chain	Residue
B	LYS14
B	SER15
B	GLY35
B	SER36
B	GLY37
B	LYS38
B	SER39
B	SER40
B	THR60
B	ILE62
B	THR63
B	LYS64
B	GLN134
B	ASP946
B	GLU947
B	LYS994
D	TYR890
D	LEU910
D	ASN914
D	SER916
D	GLU919

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG C 401

Chain	Residue
C	ASP49
C	ASN84
C	HIS158
C	HIS186
C	MG402

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MG C 402

Chain	Residue
C	ASP8
C	HIS10
C	ASP49
C	HIS188
C	MG401
C	HOH501

---

site_id	AC6
Number of Residues	22
Details	binding site for residue AGS D 1101

Chain	Residue
B	TYR890
B	LEU910
B	ASN914
B	SER916
B	GLU919
D	LYS14
D	SER15
D	GLU33
D	GLY35
D	SER36
D	GLY37
D	LYS38
D	SER39
D	SER40
D	THR60
D	ILE62
D	THR63
D	LYS64
D	GLN134
D	ASP946
D	GLU947
D	LYS994

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_02044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00449","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"3AUY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PDB","id":"3AUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AUY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00449","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---