5DMI

Structure of the extracellular domain of the CD40 in complex with CHI220 FAB

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009897	cellular_component	external side of plasma membrane
A	0038023	molecular_function	signaling receptor activity
A	0042113	biological_process	B cell activation
A	0050776	biological_process	regulation of immune response

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 H 301

Chain	Residue
H	ASP62
H	ARG66

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site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 L 301

Chain	Residue
L	HIS53
L	SER54

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR206-HIS212

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site_id	PS00652
Number of Residues	34
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Crekq..Ylinsq.....C..Csl.Cqpgqklvsd..Cteft..ETEC

Chain	Residue	Details
A	CYS26-CYS59

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site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CtCeeGWhctsea..C

Chain	Residue	Details
A	CYS103-CYS116

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASP153
A	ASP180

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