5DLQ

Crystal structure of RanGTP-Exportin 4-eIF5A complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005049	molecular_function	nuclear export signal receptor activity
A	0005634	cellular_component	nucleus
A	0005643	cellular_component	nuclear pore
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006096	biological_process	glycolytic process
A	0006611	biological_process	protein export from nucleus
A	0015031	biological_process	protein transport
A	0031267	molecular_function	small GTPase binding
A	0046827	biological_process	positive regulation of protein export from nucleus
A	0051169	biological_process	nuclear transport
B	0005049	molecular_function	nuclear export signal receptor activity
B	0005634	cellular_component	nucleus
B	0005643	cellular_component	nuclear pore
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006096	biological_process	glycolytic process
B	0006611	biological_process	protein export from nucleus
B	0015031	biological_process	protein transport
B	0031267	molecular_function	small GTPase binding
B	0046827	biological_process	positive regulation of protein export from nucleus
B	0051169	biological_process	nuclear transport
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0006913	biological_process	nucleocytoplasmic transport
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0006913	biological_process	nucleocytoplasmic transport
E	0003723	molecular_function	RNA binding
E	0003746	molecular_function	translation elongation factor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005642	cellular_component	annulate lamellae
E	0005643	cellular_component	nuclear pore
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005829	cellular_component	cytosol
E	0006412	biological_process	translation
E	0006414	biological_process	translational elongation
E	0016020	cellular_component	membrane
E	0017070	molecular_function	U6 snRNA binding
E	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
E	0043022	molecular_function	ribosome binding
E	0045202	cellular_component	synapse
E	0045901	biological_process	positive regulation of translational elongation
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0098586	biological_process	cellular response to virus
E	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
F	0003723	molecular_function	RNA binding
F	0003746	molecular_function	translation elongation factor activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005642	cellular_component	annulate lamellae
F	0005643	cellular_component	nuclear pore
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005829	cellular_component	cytosol
F	0006412	biological_process	translation
F	0006414	biological_process	translational elongation
F	0016020	cellular_component	membrane
F	0017070	molecular_function	U6 snRNA binding
F	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
F	0043022	molecular_function	ribosome binding
F	0045202	cellular_component	synapse
F	0045901	biological_process	positive regulation of translational elongation
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0098586	biological_process	cellular response to virus
F	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue GTP C 217

Chain	Residue
B	PRO974
C	LYS37
C	TYR39
C	ALA41
C	THR42
C	ALA67
C	GLY68
C	LEU69
C	ASN122
C	LYS123
C	ASP125
C	GLY19
C	ILE126
C	SER150
C	ALA151
C	LYS152
C	MG218
C	GLY20
C	GLY22
C	LYS23
C	THR24
C	THR25
C	PHE35
C	GLU36

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG C 218

Chain	Residue
C	LYS23
C	THR24
C	THR42
C	ASP65
C	THR66
C	GTP217

---

site_id	AC3
Number of Residues	24
Details	binding site for residue GTP D 217

Chain	Residue
A	PRO974
D	GLY19
D	GLY20
D	THR21
D	GLY22
D	LYS23
D	THR24
D	THR25
D	PHE35
D	GLU36
D	LYS37
D	TYR39
D	ALA41
D	THR42
D	ALA67
D	GLY68
D	ASN122
D	LYS123
D	ASP125
D	ILE126
D	SER150
D	ALA151
D	LYS152
D	MG218

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG D 218

Chain	Residue
D	LYS23
D	THR24
D	THR42
D	ASP65
D	GTP217

---

Functional Information from PROSITE/UniProt

site_id	PS00302
Number of Residues	8
Details	IF5A_HYPUSINE Eukaryotic initiation factor 5A hypusine signature. TGKHGhAK

Chain	Residue	Details
F	THR48-LYS55

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	328
Details	Domain: {"description":"Small GTPase Ran-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Site: {"description":"Essential for GTP hydrolysis","evidences":[{"source":"PubMed","id":"18591255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8636225","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"31075303","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"29040603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62827","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19379712","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Modified residue: {"description":"Hypusine","evidences":[{"source":"PubMed","id":"27306458","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3095320","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P63242","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---