Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | TRP268 |
| A | ARG416 |
| A | PHE417 |
| A | ASP418 |
| A | HOH838 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | TRP268 |
| A | GLN437 |
| A | HOH628 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | VAL42 |
| A | ILE43 |
| A | PRO44 |
| A | HOH807 |
| A | HOH818 |
| D | PRO129 |
| A | ASN41 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | VAL61 |
| A | PRO384 |
| A | LEU385 |
| A | HOH787 |
| A | HOH882 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | LYS241 |
| A | SER297 |
| A | PHE338 |
| A | HOH625 |
| A | HOH894 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | TYR298 |
| A | THR476 |
| A | PHE477 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 507 |
| Chain | Residue |
| A | PHE62 |
| A | HIS69 |
| A | HIS179 |
| A | TRP268 |
| A | PHE417 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue DMS A 508 |
| Chain | Residue |
| A | THR310 |
| A | VAL311 |
| A | ASN312 |
| A | LEU329 |
| A | GLN390 |
| A | HIS391 |
| A | GLN392 |
| A | ILE394 |
| A | HOH898 |
| A | HOH923 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ASN41 |
| B | VAL42 |
| B | ILE43 |
| B | PRO44 |
| B | HOH629 |
| B | HOH834 |
| C | PRO129 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | VAL61 |
| B | LEU369 |
| B | PRO384 |
| B | LEU385 |
| B | HOH760 |
| B | HOH794 |
| B | HOH864 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ALA415 |
| B | PHE417 |
| B | EDO504 |
| B | EDO506 |
| B | DMS507 |
| B | HOH616 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | TRP268 |
| B | ARG416 |
| B | PHE417 |
| B | ASP418 |
| B | EDO503 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | TYR298 |
| B | ILE475 |
| B | THR476 |
| B | PHE477 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | PHE270 |
| B | GLN437 |
| B | EDO503 |
| B | HOH636 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 507 |
| Chain | Residue |
| B | PHE62 |
| B | HIS69 |
| B | HIS179 |
| B | TRP268 |
| B | PHE417 |
| B | EDO503 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue DMS B 508 |
| Chain | Residue |
| B | THR310 |
| B | VAL311 |
| B | ASN312 |
| B | LEU329 |
| B | GLN390 |
| B | HIS391 |
| B | GLN392 |
| B | HOH643 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | ASN41 |
| C | VAL42 |
| C | ILE43 |
| C | PRO44 |
| C | HOH601 |
| C | HOH785 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | LEU385 |
| C | ILE388 |
| C | HOH714 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | TRP268 |
| C | ARG416 |
| C | PHE417 |
| C | ASP418 |
| C | HOH712 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 504 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue DMS C 505 |
| Chain | Residue |
| C | THR67 |
| C | HIS69 |
| C | HIS179 |
| C | PHE417 |
| C | PHE426 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS C 506 |
| Chain | Residue |
| C | ASN312 |
| C | HIS391 |
| C | GLN392 |
| C | ASN393 |
| C | ILE394 |
| C | HOH748 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 501 |
| Chain | Residue |
| D | ASN41 |
| D | VAL42 |
| D | ILE43 |
| D | PRO44 |
| D | HOH601 |
| D | HOH833 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| D | VAL61 |
| D | PHE331 |
| D | LEU369 |
| D | LEU385 |
| D | HOH702 |
| D | HOH754 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue DMS D 503 |
| Chain | Residue |
| D | THR67 |
| D | HIS69 |
| D | TRP268 |
| D | PHE417 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue DMS D 504 |
| Chain | Residue |
| D | LEU329 |
| D | GLN392 |
| D | HOH771 |
