Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | HIS519 |
| A | HIS553 |
| A | ASP554 |
| A | ASP664 |
| A | HOH907 |
| A | HOH909 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 802 |
| Chain | Residue |
| A | HOH907 |
| A | HOH926 |
| A | HOH927 |
| A | ASP554 |
| A | HOH901 |
| A | HOH905 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue 5AV A 803 |
| Chain | Residue |
| A | TYR514 |
| A | HIS515 |
| A | LEU665 |
| A | SER667 |
| A | VAL668 |
| A | ILE682 |
| A | PHE686 |
| A | GLN716 |
| A | PHE719 |
| A | 4PX804 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue 4PX A 804 |
| Chain | Residue |
| A | TYR514 |
| A | HIS515 |
| A | LEU625 |
| A | ASP664 |
| A | LEU665 |
| A | SER667 |
| A | ALA679 |
| A | ILE682 |
| A | PHE686 |
| A | MET703 |
| A | GLN716 |
| A | PHE719 |
| A | 5AV803 |
| A | HOH906 |
| A | HOH909 |
| A | HOH922 |
| A | HOH926 |
| B | GLY697 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | HIS519 |
| B | HIS553 |
| B | ASP554 |
| B | ASP664 |
| B | HOH909 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 802 |
| Chain | Residue |
| B | ASP554 |
| B | HOH902 |
| B | HOH908 |
| B | HOH909 |
| B | HOH912 |
| B | HOH926 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue 5AV B 803 |
| Chain | Residue |
| B | TYR514 |
| B | HIS515 |
| B | LEU665 |
| B | SER667 |
| B | VAL668 |
| B | ILE682 |
| B | PHE686 |
| B | GLN716 |
| B | PHE719 |
| B | HOH939 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS553-TYR564 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 317 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
