5DFD
Crystal structure of BRD2(BD2) W370F mutant with ligand 28 bound
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue 59E A 501 |
| Chain | Residue |
| A | PRO371 |
| A | LEU383 |
| A | ASN429 |
| A | HIS433 |
| A | VAL435 |
| A | HOH606 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | LYS441 |
| A | HOH603 |
| A | HOH604 |
| A | HOH619 |
| A | LYS402 |
| A | ASP407 |
| A | MET438 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AfpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
