5DEP
Structure of Pseudomonas aeruginosa LpxA in complex with UDP-GlcNAc
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| C | 0009245 | biological_process | lipid A biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008610 | biological_process | lipid biosynthetic process |
| D | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| D | 0009245 | biological_process | lipid A biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008610 | biological_process | lipid biosynthetic process |
| E | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| E | 0009245 | biological_process | lipid A biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008610 | biological_process | lipid biosynthetic process |
| F | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| F | 0009245 | biological_process | lipid A biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 B 301 |
| Chain | Residue |
| B | SER192 |
| B | MET193 |
| B | ARG212 |
| B | TYR215 |
| B | LYS216 |
| B | ARG220 |
| F | GLU189 |
| F | ARG191 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue UD1 B 302 |
| Chain | Residue |
| A | ILE148 |
| A | PHE166 |
| A | ASN194 |
| A | ARG200 |
| A | ARG201 |
| B | ASP70 |
| B | LEU71 |
| B | LYS72 |
| B | HIS121 |
| B | HIS140 |
| B | HIS156 |
| B | GLN157 |
| B | TYR158 |
| B | HOH402 |
| B | HOH456 |
| A | ILE130 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue UD1 B 303 |
| Chain | Residue |
| A | LEU3 |
| A | ASP5 |
| A | ARG7 |
| B | ASP11 |
| B | GLY29 |
| B | ALA30 |
| B | GLU31 |
| B | LYS47 |
| B | GLY48 |
| B | ASP67 |
| B | ARG96 |
| B | HOH410 |
| B | HOH441 |
| B | HOH442 |
| D | MET1 |
| D | SER2 |
| D | LEU3 |
| D | HOH433 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 B 304 |
| Chain | Residue |
| B | HIS223 |
| B | GLU227 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| D | HIS110 |
| D | HIS128 |
| D | TRP146 |
| F | LEU71 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue UD1 D 302 |
| Chain | Residue |
| D | HIS128 |
| D | TRP146 |
| D | HIS164 |
| D | ARG201 |
| D | GLY202 |
| D | PHE203 |
| D | SER204 |
| D | GLU241 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 E 301 |
| Chain | Residue |
| E | PHE166 |
| E | ASN194 |
| E | ARG200 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue UD1 E 302 |
| Chain | Residue |
| E | ASP70 |
| E | LYS72 |
| E | HIS121 |
| E | GLN157 |
| E | TYR158 |
| F | ILE148 |
| F | PHE166 |
| F | ASN194 |
| F | ARG200 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue UD1 F 301 |
| Chain | Residue |
| D | ILE148 |
| D | PHE166 |
| D | ASN194 |
| D | ARG200 |
| D | ARG201 |
| D | HOH450 |
| F | ASP70 |
| F | LEU71 |
| F | LYS72 |
| F | HIS121 |
| F | HIS140 |
| F | GLN157 |
| F | TYR158 |
| F | HOH411 |
| F | HOH433 |
| F | HOH455 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for residue UD1 F 302 |
| Chain | Residue |
| F | HOH404 |
| F | HOH414 |
| A | SER2 |
| A | LEU3 |
| A | HOH344 |
| D | LEU3 |
| D | ASP5 |
| D | ARG7 |
| F | ILE9 |
| F | ASP11 |
| F | ILE27 |
| F | GLY29 |
| F | ALA30 |
| F | LYS47 |
| F | GLY48 |
| F | ASP67 |
| F | ARG96 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IDprAiIdpsArLAadVqVGpwSiVgaeV |
| Chain | Residue | Details |
| A | ILE4-VAL32 |
