5DCL
Structure of a lantibiotic response regulator: N terminal domain of the nisin resistance regulator NsrR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000156 | molecular_function | phosphorelay response regulator activity |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| B | 0000156 | molecular_function | phosphorelay response regulator activity |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0032993 | cellular_component | protein-DNA complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | LYS41 |
| A | TYR65 |
| A | GLU69 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ASP13 |
| A | PRO59 |
| A | TYR60 |
| A | PHE61 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | SER33 |
| A | SER35 |
| A | EDO304 |
| B | EDO309 |
| A | LYS22 |
| A | SER32 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | SER32 |
| A | SER33 |
| A | SER35 |
| A | GLU43 |
| A | PHE47 |
| A | EDO303 |
| B | SER107 |
| B | EDO309 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | LYS41 |
| A | ILE45 |
| A | PHE73 |
| A | LEU74 |
| A | EDO312 |
| A | HOH401 |
| B | LYS72 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ILE44 |
| A | GLN48 |
| A | PRO49 |
| A | ILE76 |
| A | EDO312 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLU12 |
| A | MET15 |
| A | SER33 |
| A | VAL34 |
| A | EDO308 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | VAL34 |
| A | SER35 |
| A | PHE37 |
| A | EDO307 |
| B | PRO105 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | THR57 |
| A | SER83 |
| A | LYS104 |
| A | EDO313 |
| B | EDO313 |
| B | HOH440 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | ILE56 |
| A | THR57 |
| A | PHE64 |
| A | HOH423 |
| B | TYR65 |
| B | EDO313 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | LEU20 |
| A | PRO105 |
| A | PHE106 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | ILE45 |
| A | GLN48 |
| A | EDO305 |
| A | EDO306 |
| A | HOH401 |
| B | LYS72 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | ASP14 |
| A | LYS104 |
| A | EDO309 |
| A | HOH418 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 314 |
| Chain | Residue |
| A | ASP99 |
| A | ALA117 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 315 |
| Chain | Residue |
| A | LYS72 |
| A | PHE73 |
| A | THR75 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 316 |
| Chain | Residue |
| A | LYS72 |
| A | HOH403 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 317 |
| Chain | Residue |
| A | GLN5 |
| A | SER26 |
| A | TYR29 |
| A | HIS30 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 318 |
| Chain | Residue |
| A | ASP89 |
| A | MET90 |
| A | PHE101 |
| A | VAL110 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| B | SER28 |
| B | TYR29 |
| B | ASP112 |
| B | HOH405 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | ILE45 |
| B | ASP89 |
| B | MET90 |
| B | PHE101 |
| B | EDO311 |
| B | HOH448 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | ARG38 |
| B | LYS41 |
| B | GLN42 |
| B | TRP66 |
| B | HOH407 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ASP13 |
| B | ASP55 |
| B | THR57 |
| B | LEU58 |
| B | LYS104 |
| B | HOH466 |
| B | GLU12 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | LYS22 |
| B | SER32 |
| B | SER33 |
| B | VAL34 |
| B | HOH461 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | ASP13 |
| B | ASP14 |
| B | MET15 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | ASP13 |
| B | LEU58 |
| B | PRO59 |
| B | TYR60 |
| B | PHE61 |
| B | HOH409 |
| B | HOH453 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | GLU4 |
| B | GLU4 |
| B | LYS22 |
| B | SER26 |
| B | TYR29 |
| B | HIS30 |
| B | VAL31 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| A | EDO303 |
| A | EDO304 |
| B | SER107 |
| B | LEU108 |
| B | ALA109 |
| B | EDO317 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | LYS41 |
| B | TYR65 |
| B | TRP66 |
| B | GLU69 |
| B | ALA117 |
| B | HOH431 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| A | GLN42 |
| B | MET90 |
| B | ASP100 |
| B | PHE101 |
| B | LYS114 |
| B | EDO302 |
| B | EDO318 |
| B | HOH457 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | ARG71 |
| B | HOH401 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 313 |
| Chain | Residue |
| A | SER83 |
| A | EDO309 |
| A | EDO310 |
| B | ALA68 |
| B | GLU69 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 314 |
| Chain | Residue |
| B | ARG38 |
| B | THR75 |
| B | PRO77 |
| B | EDO321 |
| B | HOH402 |
| B | HOH426 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 315 |
| Chain | Residue |
| B | ALA46 |
| B | VAL91 |
| B | ASN95 |
| site_id | AF7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 316 |
| Chain | Residue |
| B | PRO105 |
| B | PHE106 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 317 |
| Chain | Residue |
| B | HIS24 |
| B | ALA109 |
| B | ASP112 |
| B | EDO309 |
| B | HOH410 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 318 |
| Chain | Residue |
| A | ASN36 |
| A | ARG38 |
| B | SER103 |
| B | EDO311 |
| B | HOH404 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 319 |
| Chain | Residue |
| B | VAL34 |
| B | SER35 |
| B | PHE37 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 320 |
| Chain | Residue |
| A | GLN42 |
| A | ILE45 |
| B | LYS41 |
| B | LYS114 |
| site_id | AG3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 321 |
| Chain | Residue |
| B | ASN85 |
| B | EDO314 |
