5D7X
Crystal structure of the human BRPF1 bromodomain in complex with XZ08
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 801 |
| Chain | Residue |
| A | GLY650 |
| A | ILE652 |
| A | LEU688 |
| A | ASN689 |
| A | ALA717 |
| A | ARG720 |
| A | HOH917 |
| A | HOH1027 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue XZ8 A 802 |
| Chain | Residue |
| A | PHE653 |
| A | GLU655 |
| A | PRO656 |
| A | VAL657 |
| A | PRO658 |
| A | ASN708 |
| A | PHE714 |
| A | HOH928 |
| A | HOH939 |
| A | HOH959 |
| A | HOH1038 |
| A | ILE652 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
