5D4U
SAM-bound HcgC from Methanocaldococcus jannaschii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| A | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| A | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| B | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| B | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| B | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| C | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| C | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| C | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| D | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| D | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| D | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SAM A 301 |
| Chain | Residue |
| A | LYS34 |
| A | LEU117 |
| A | THR118 |
| A | GLY122 |
| A | ILE123 |
| A | GLU139 |
| A | GLY184 |
| A | THR185 |
| A | SO4302 |
| A | HOH402 |
| A | HOH424 |
| A | GLY54 |
| A | HOH476 |
| A | TYR56 |
| A | LEU57 |
| A | TRP58 |
| A | ASP77 |
| A | ILE78 |
| A | HIS79 |
| A | LEU97 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | TYR56 |
| A | GLY184 |
| A | MET186 |
| A | THR187 |
| A | SAM301 |
| A | HOH402 |
| A | HOH418 |
| A | HOH477 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | HIS79 |
| A | GLU80 |
| A | PHE81 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG106 |
| A | GLU108 |
| A | HOH433 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residue SAM B 301 |
| Chain | Residue |
| B | LYS34 |
| B | GLY54 |
| B | TYR56 |
| B | LEU57 |
| B | TRP58 |
| B | ASP77 |
| B | ILE78 |
| B | HIS79 |
| B | MET82 |
| B | LEU117 |
| B | THR118 |
| B | ILE123 |
| B | GLU139 |
| B | GLY184 |
| B | THR185 |
| B | SO4302 |
| B | HOH406 |
| B | HOH469 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | TYR56 |
| B | GLY184 |
| B | MET186 |
| B | THR187 |
| B | SAM301 |
| B | HOH401 |
| B | HOH404 |
| B | HOH406 |
| B | HOH434 |
| B | HOH466 |
| B | HOH482 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| A | TYR150 |
| B | ASP140 |
| B | LYS142 |
| B | TYR156 |
| B | LYS172 |
| B | HOH430 |
| B | HOH451 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | HIS79 |
| B | GLU80 |
| B | PHE81 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | ASP225 |
| B | HIS227 |
| B | LYS228 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 306 |
| Chain | Residue |
| B | ARG214 |
| B | GLU232 |
| D | ARG214 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 307 |
| Chain | Residue |
| B | ARG178 |
| B | GLU199 |
| B | ASN256 |
| B | ASN257 |
| B | LEU260 |
| B | HOH403 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for residue SAM C 301 |
| Chain | Residue |
| C | GLY184 |
| C | THR185 |
| C | HOH403 |
| C | LYS34 |
| C | GLY54 |
| C | TYR56 |
| C | LEU57 |
| C | TRP58 |
| C | ASP77 |
| C | ILE78 |
| C | HIS79 |
| C | MET82 |
| C | LEU117 |
| C | THR118 |
| C | GLY122 |
| C | ILE123 |
| C | GLU139 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | ASP140 |
| C | LYS142 |
| C | TYR156 |
| C | LYS172 |
| C | HOH422 |
| C | HOH469 |
| D | PHE145 |
| D | TYR150 |
| D | HOH451 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| C | HIS79 |
| C | GLU80 |
| C | PHE81 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| A | TYR208 |
| C | TYR56 |
| C | GLY184 |
| C | MET186 |
| C | THR187 |
| C | HOH403 |
| C | HOH437 |
| site_id | AD7 |
| Number of Residues | 19 |
| Details | binding site for residue SAM D 301 |
| Chain | Residue |
| D | LYS34 |
| D | GLY54 |
| D | TYR56 |
| D | LEU57 |
| D | TRP58 |
| D | ASP77 |
| D | ILE78 |
| D | HIS79 |
| D | MET82 |
| D | LEU117 |
| D | THR118 |
| D | GLY122 |
| D | ILE123 |
| D | GLU139 |
| D | GLY184 |
| D | THR185 |
| D | SO4302 |
| D | HOH401 |
| D | HOH434 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| B | TYR208 |
| D | TYR56 |
| D | GLY184 |
| D | MET186 |
| D | THR187 |
| D | GLU217 |
| D | SAM301 |
| D | HOH401 |
| D | HOH473 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | HIS79 |
| D | GLU80 |
| D | PHE81 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| C | ASN88 |
| D | TYR35 |
| D | ARG39 |
| D | MET65 |
| D | LYS68 |
| D | TYR69 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 305 |
| Chain | Residue |
| D | ASN110 |
| D | PRO111 |
| D | ASP112 |
| D | ASN132 |
