5D3Q

Dynamin 1 GTPase-BSE fusion dimer complexed with GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue GDP A 801

Chain	Residue
A	SER41
A	LEU209
A	VAL235
A	ASN236
A	ARG237
A	SER238
A	GLN239
A	ILE242
A	EDO802
A	HOH912
A	HOH964
A	ALA42
A	HOH1099
B	ASP211
B	HOH974
A	GLY43
A	LYS44
A	SER45
A	SER46
A	ARG59
A	LYS206
A	ASP208

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO A 802

Chain	Residue
A	SER45
A	PRO58
A	ARG59
A	GDP801
A	HOH1009

---

site_id	AC3
Number of Residues	22
Details	binding site for residue GDP B 801

Chain	Residue
A	ASP211
A	HOH987
B	SER41
B	ALA42
B	GLY43
B	LYS44
B	SER45
B	SER46
B	ARG59
B	LYS206
B	ASP208
B	LEU209
B	VAL235
B	ASN236
B	ARG237
B	SER238
B	GLN239
B	HOH916
B	HOH1009
B	HOH1073
B	HOH1077
B	HOH1102

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO B 802

Chain	Residue
B	LEU207
B	ASP208
B	MET210
B	HIS262
B	HOH940

---

Functional Information from PROSITE/UniProt

site_id	PS00410
Number of Residues	10
Details	G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR

Chain	Residue	Details
A	LEU57-ARG66

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:20428113, ECO:0000269|PubMed:26612256, ECO:0007744|PDB:5D3Q

Chain	Residue	Details
B	SER41
A	SER41

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:20428113, ECO:0000269|PubMed:26612256, ECO:0007744|PDB:2X2E, ECO:0007744|PDB:2X2F, ECO:0007744|PDB:5D3Q

Chain	Residue	Details
A	LYS206
A	ASP208
B	GLY43
B	SER45
B	LYS206
B	ASP208
A	GLY43
A	SER45

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:20428113, ECO:0000269|PubMed:26612256, ECO:0000269|PubMed:30069048, ECO:0007744|PDB:2X2E, ECO:0007744|PDB:2X2F, ECO:0007744|PDB:5D3Q, ECO:0007744|PDB:6DLU

Chain	Residue	Details
B	GLN239
A	ASN236
A	ARG237
A	GLN239
B	LYS44
B	SER46
B	ASN236
B	ARG237
A	LYS44
A	SER46

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:26612256, ECO:0007744|PDB:5D3Q

Chain	Residue	Details
A	ARG59
B	ARG59

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:20428113, ECO:0007744|PDB:2X2E, ECO:0007744|PDB:2X2F

Chain	Residue	Details
A	GLY60
B	GLY60

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:20428113, ECO:0000269|PubMed:26612256, ECO:0000269|PubMed:30069048, ECO:0007744|PDB:2X2E, ECO:0007744|PDB:5D3Q, ECO:0007744|PDB:6DLU

Chain	Residue	Details
A	ASP211
B	ASP211

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P39053

Chain	Residue	Details
A	TYR80
B	TYR80

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphotyrosine; alternate => ECO:0000250|UniProtKB:P39053

Chain	Residue	Details
A	TYR125
B	TYR125

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P39053

Chain	Residue	Details
A	SER306
B	SER306

---