5CZG
Crystal Structure Analysis of hypothetical bromodomain Tb427.10.7420 from Trypanosoma brucei in complex with bromosporine
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 501 |
| Chain | Residue |
| A | GLY0 |
| A | ASP42 |
| A | HOH614 |
| A | HOH649 |
| A | HOH649 |
| A | HOH689 |
| A | HOH689 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 502 |
| Chain | Residue |
| A | PHE10 |
| A | HOH618 |
| A | HOH668 |
| A | HOH685 |
| A | ASN4 |
| A | ASP7 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue BMF A 503 |
| Chain | Residue |
| A | MET30 |
| A | VAL35 |
| A | GLU39 |
| A | LEU40 |
| A | TYR85 |
| A | ASN86 |
| A | TRP92 |
| A | HOH606 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 53 |
| Details | BROMODOMAIN_1 Bromodomain signature. HpvSaeelP.......DYHtvIkrpVdlssIrdgiekgt..Yatdvdvqndvar.MitNAleY |
| Chain | Residue | Details |
| A | HIS33-TYR85 |
