Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue T27 A 601 |
| Chain | Residue |
| A | LEU100 |
| A | PRO236 |
| A | TYR318 |
| A | HOH866 |
| B | GLU138 |
| B | HOH619 |
| A | LYS101 |
| A | LYS103 |
| A | TYR181 |
| A | TYR188 |
| A | PHE227 |
| A | TRP229 |
| A | LEU234 |
| A | HIS235 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue BYZ A 602 |
| Chain | Residue |
| A | ILE5 |
| A | ALA114 |
| A | VAL118 |
| A | PHE160 |
| A | SER163 |
| A | MET164 |
| A | LEU214 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue BYZ A 603 |
| Chain | Residue |
| A | ALA172 |
| A | ILE180 |
| B | THR139 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue BYZ A 604 |
| Chain | Residue |
| A | GLY93 |
| A | TYR181 |
| B | ASN137 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue BYZ A 605 |
| Chain | Residue |
| A | ARG356 |
| A | SER513 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue BYZ A 606 |
| Chain | Residue |
| A | VAL21 |
| A | PRO55 |
| A | ASN57 |
| A | ARG143 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue BYZ A 607 |
| Chain | Residue |
| A | GLY453 |
| A | LYS461 |
| A | HOH886 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue BYZ A 608 |
| Chain | Residue |
| A | ASP443 |
| A | ALA445 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue BYZ A 609 |
| Chain | Residue |
| A | TYR441 |
| A | GLY456 |
| A | TYR457 |
| A | GLY544 |
| A | ASN545 |
| A | GLU546 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 610 |
| Chain | Residue |
| A | ARG448 |
| A | THR473 |
| A | ASN474 |
| A | GLN475 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 611 |
| Chain | Residue |
| A | GLY333 |
| A | GLN334 |
| A | LYS512 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 612 |
| Chain | Residue |
| A | TRP426 |
| A | TYR427 |
| A | GLN428 |
| A | LEU525 |
| A | LYS528 |
| A | GLU529 |
| A | HOH734 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 613 |
| Chain | Residue |
| A | TRP426 |
| A | TYR427 |
| A | GLN509 |
| A | PRO510 |
| A | ASP511 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue BR A 614 |
| Chain | Residue |
| A | LYS388 |
| A | PHE389 |
| A | LYS390 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 615 |
| Chain | Residue |
| A | GLN242 |
| A | TRP266 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 616 |
| Chain | Residue |
| A | LYS46 |
| A | PHE116 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue BYZ B 501 |
| Chain | Residue |
| B | ALA114 |
| B | LEU209 |
| B | TRP212 |
| B | LEU228 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue BYZ B 502 |
| Chain | Residue |
| A | ILE380 |
| A | VAL381 |
| B | LEU26 |
| B | ILE31 |
| B | PRO133 |
| B | SER134 |
| B | ASN137 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue BYZ B 503 |
| Chain | Residue |
| B | TYR232 |
| B | LEU234 |
| B | TRP239 |
| B | LYS374 |
| B | GLU378 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue BYZ B 504 |
| Chain | Residue |
| B | TYR232 |
| B | ARG358 |
| B | THR377 |
| B | BYZ506 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue BYZ B 505 |
| Chain | Residue |
| B | PRO247 |
| B | LYS249 |
| B | ASP256 |
| B | LYS259 |
| B | HOH618 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue BYZ B 506 |
| Chain | Residue |
| B | THR409 |
| B | BYZ504 |
| B | LYS65 |
| B | ASP186 |
| B | GLN407 |
| B | ALA408 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue BYZ B 507 |
| Chain | Residue |
| B | VAL75 |
| B | ASP76 |
| B | PHE77 |
| B | ARG78 |
| B | GLY152 |
| B | THR409 |
| B | TRP410 |
| B | ILE411 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 508 |
| Chain | Residue |
| A | THR376 |
| B | THR27 |
| B | THR400 |
| B | GLU404 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS B 509 |
| Chain | Residue |
| A | GLN85 |
| B | TYR56 |
| B | LYS126 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 510 |
| Chain | Residue |
| B | GLN242 |
| B | PRO243 |
| B | ILE244 |
| B | LYS263 |
| B | TRP426 |
| B | GLN428 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue DMS B 511 |
| Chain | Residue |
| A | GLU138 |
| B | GLN269 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 512 |
| Chain | Residue |
| B | TRP24 |
| B | GLU399 |
| B | TRP402 |
| B | HOH673 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue DMS B 513 |
| Chain | Residue |
| B | TRP337 |
| B | TYR354 |
| B | ARG356 |
| B | MET357 |
| B | GLN367 |
| B | GLU370 |
| B | ALA371 |
| B | LYS374 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ASP110 | |
| B | ASP185 | |
| B | ASP186 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Essential for RT p66/p51 heterodimerization |
| Chain | Residue | Details |
| B | TRP401 | |
| B | TRP414 | |
| A | ASP498 | |
| A | ASP549 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Essential for RT p66/p51 heterodimerization |
| Chain | Residue | Details |
| A | TRP401 | |
| A | TRP414 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by viral protease; partial |
| Chain | Residue | Details |
| A | PHE440 | |
