5CXI
Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA (4-BNC-CoA)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue 5TW A 201 |
| Chain | Residue |
| A | GLU71 |
| A | PHE72 |
| A | ALA103 |
| A | LEU110 |
| A | MET114 |
| A | TYR118 |
| A | ARG158 |
| A | SER161 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 5TW B 201 |
| Chain | Residue |
| B | ALA103 |
| B | MET114 |
| B | ILE136 |
| B | ARG158 |
| B | SER161 |
| B | HOH360 |
| B | GLU71 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335 |
| Chain | Residue | Details |
| A | GLN38-PHE57 | |
| B | GLN38-PHE57 |
