5CVJ
Monolignol 4-O-methyltransferase 5 - coniferyl alcohol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0050630 | molecular_function | (iso)eugenol O-methyltransferase activity |
| A | 0102719 | molecular_function | S-adenosyl-L-methionine:eugenol-O-methyltransferase activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0046983 | molecular_function | protein dimerization activity |
| B | 0050630 | molecular_function | (iso)eugenol O-methyltransferase activity |
| B | 0102719 | molecular_function | S-adenosyl-L-methionine:eugenol-O-methyltransferase activity |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0008171 | molecular_function | O-methyltransferase activity |
| C | 0032259 | biological_process | methylation |
| C | 0046983 | molecular_function | protein dimerization activity |
| C | 0050630 | molecular_function | (iso)eugenol O-methyltransferase activity |
| C | 0102719 | molecular_function | S-adenosyl-L-methionine:eugenol-O-methyltransferase activity |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008171 | molecular_function | O-methyltransferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0046983 | molecular_function | protein dimerization activity |
| D | 0050630 | molecular_function | (iso)eugenol O-methyltransferase activity |
| D | 0102719 | molecular_function | S-adenosyl-L-methionine:eugenol-O-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue SAH D 401 |
| Chain | Residue |
| D | TRP166 |
| D | MET255 |
| D | LYS268 |
| D | ASP273 |
| D | TRP274 |
| D | N7I402 |
| D | HOH507 |
| D | HOH526 |
| D | HOH585 |
| D | HOH596 |
| D | HOH613 |
| D | MET183 |
| D | HOH616 |
| D | HOH625 |
| D | SER187 |
| D | GLY211 |
| D | GLY213 |
| D | ASP234 |
| D | LEU235 |
| D | VAL238 |
| D | ASP254 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue N7I D 402 |
| Chain | Residue |
| D | PHE130 |
| D | LEU133 |
| D | ALA134 |
| D | ILE165 |
| D | TRP166 |
| D | TRP269 |
| D | HIS272 |
| D | ASP273 |
| D | TYR326 |
| D | ASN327 |
| D | SAH401 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 D 403 |
| Chain | Residue |
| D | TYR198 |
| D | ASN199 |
| D | GLY200 |
| D | LYS351 |
| D | ALA353 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 D 404 |
| Chain | Residue |
| D | ASN121 |
| D | ASP123 |
| D | THR188 |
| D | ILE189 |
| D | LYS192 |
| D | HOH535 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 D 405 |
| Chain | Residue |
| D | LYS120 |
| D | GLY124 |
| D | VAL125 |
| D | SER126 |
| D | PRO129 |
| D | LYS181 |
| D | SER185 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | TRP166 |
| A | MET183 |
| A | SER187 |
| A | GLY211 |
| A | ASP234 |
| A | LEU235 |
| A | VAL238 |
| A | ASP254 |
| A | MET255 |
| A | PHE256 |
| A | LYS268 |
| A | TRP269 |
| A | ILE270 |
| A | ASP273 |
| A | N7I402 |
| A | HOH508 |
| A | HOH556 |
| A | HOH564 |
| A | HOH605 |
| A | HOH626 |
| A | HOH632 |
| A | HOH653 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue N7I A 402 |
| Chain | Residue |
| A | LEU133 |
| A | ALA134 |
| A | LEU139 |
| A | TRP166 |
| A | PHE179 |
| A | TRP269 |
| A | HIS272 |
| A | ASP273 |
| A | LEU322 |
| A | TYR326 |
| A | ASN327 |
| A | SAH401 |
| A | HOH533 |
| A | HOH685 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 403 |
| Chain | Residue |
| A | LYS120 |
| A | GLY124 |
| A | VAL125 |
| A | SER126 |
| A | PRO129 |
| A | LYS181 |
| A | SER185 |
| A | HOH505 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 404 |
| Chain | Residue |
| A | LYS192 |
| A | HOH581 |
| A | ASN121 |
| A | ASP123 |
| A | VAL125 |
| A | THR188 |
| A | ILE189 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 A 405 |
| Chain | Residue |
| A | ALA134 |
| A | THR135 |
| A | ASP136 |
| A | LEU139 |
| A | LEU140 |
| site_id | AD2 |
| Number of Residues | 22 |
| Details | binding site for residue SAH B 401 |
| Chain | Residue |
| B | TRP166 |
| B | MET183 |
| B | SER187 |
| B | GLY211 |
| B | GLY213 |
| B | ASP234 |
| B | LEU235 |
| B | VAL238 |
| B | ASP254 |
| B | MET255 |
| B | LYS268 |
| B | ILE270 |
| B | ASP273 |
| B | TRP274 |
| B | N7I402 |
| B | HOH533 |
| B | HOH535 |
| B | HOH587 |
| B | HOH606 |
| B | HOH626 |
| B | HOH632 |
| B | HOH649 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue N7I B 402 |
| Chain | Residue |
| B | ALA134 |
| B | ILE165 |
| B | TRP166 |
| B | MET183 |
| B | TRP269 |
| B | HIS272 |
| B | ASP273 |
| B | LEU322 |
| B | MET323 |
| B | TYR326 |
| B | ASN327 |
| B | SAH401 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 B 403 |
| Chain | Residue |
| B | LYS120 |
| B | GLY124 |
| B | VAL125 |
| B | SER126 |
| B | PRO129 |
| B | LYS181 |
| B | SER185 |
| B | HOH508 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 B 404 |
| Chain | Residue |
| B | PRO101 |
| B | SER102 |
| B | ASP276 |
| B | GLU277 |
| B | LEU280 |
| B | HOH529 |
| B | HOH534 |
| B | HOH564 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 B 405 |
| Chain | Residue |
| B | GLY153 |
| B | GLY154 |
| B | ILE155 |
| B | ASN158 |
| B | LYS159 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 B 406 |
| Chain | Residue |
| B | PHE233 |
| B | LEU251 |
| B | VAL259 |
| B | PRO260 |
| B | HOH571 |
| B | HOH574 |
| B | HOH644 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 B 407 |
| Chain | Residue |
| B | TYR198 |
| B | ASN199 |
| B | GLY200 |
| B | LYS351 |
| B | ALA353 |
| B | HOH540 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 B 408 |
| Chain | Residue |
| B | PRO291 |
| B | ASP292 |
| B | HIS293 |
| B | GLY294 |
| B | HOH613 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue NO3 B 409 |
| Chain | Residue |
| B | PRO226 |
| B | ILE228 |
| B | GLY247 |
| B | HOH506 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 B 410 |
| Chain | Residue |
| B | THR72 |
| B | HOH520 |
| D | GLU152 |
| site_id | AE3 |
| Number of Residues | 22 |
| Details | binding site for residue SAH C 401 |
| Chain | Residue |
| C | TRP166 |
| C | MET183 |
| C | SER187 |
| C | GLY211 |
| C | GLY213 |
| C | ASP234 |
| C | LEU235 |
| C | VAL238 |
| C | ASP254 |
| C | MET255 |
| C | PHE256 |
| C | LYS268 |
| C | ILE270 |
| C | ASP273 |
| C | N7I402 |
| C | HOH510 |
| C | HOH549 |
| C | HOH589 |
| C | HOH600 |
| C | HOH613 |
| C | HOH634 |
| C | HOH643 |
| site_id | AE4 |
| Number of Residues | 12 |
| Details | binding site for residue N7I C 402 |
| Chain | Residue |
| C | LEU133 |
| C | ALA134 |
| C | TRP166 |
| C | PHE179 |
| C | TRP269 |
| C | HIS272 |
| C | ASP273 |
| C | LEU322 |
| C | MET323 |
| C | TYR326 |
| C | ASN327 |
| C | SAH401 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 C 403 |
| Chain | Residue |
| C | PRO101 |
| C | SER102 |
| C | ASP276 |
| C | GLU277 |
| C | LEU280 |
| C | HOH503 |
| C | HOH516 |
| C | HOH556 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 C 404 |
| Chain | Residue |
| C | MET197 |
| C | TYR198 |
| C | ASN199 |
| C | GLY200 |
| C | LYS351 |
| C | ALA353 |
| C | HOH532 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 C 405 |
| Chain | Residue |
| C | LYS120 |
| C | GLY124 |
| C | VAL125 |
| C | SER126 |
| C | PRO129 |
| C | LYS181 |
| C | SER185 |
| C | HOH501 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue NO3 C 406 |
| Chain | Residue |
| C | GLY154 |
| C | ILE155 |
| C | ASN158 |
| C | LYS159 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01020 |
| Chain | Residue | Details |
| D | HIS272 | |
| A | HIS272 | |
| B | HIS272 | |
| C | HIS272 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22851762 |
| Chain | Residue | Details |
| D | SER187 | |
| A | LYS268 | |
| B | SER187 | |
| B | GLY211 | |
| B | ASP234 | |
| B | ASP254 | |
| B | LYS268 | |
| C | SER187 | |
| C | GLY211 | |
| C | ASP234 | |
| C | ASP254 | |
| D | GLY211 | |
| C | LYS268 | |
| D | ASP234 | |
| D | ASP254 | |
| D | LYS268 | |
| A | SER187 | |
| A | GLY211 | |
| A | ASP234 | |
| A | ASP254 |
