Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5CV4

Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/V66H at cryogenic temperature

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004518molecular_functionnuclease activity
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue CA A 201
ChainResidue
AASP21
AASP40
ATHR41
AGLU43
ATHP202
AHOH305
AHOH315

site_idAC2
Number of Residues23
Detailsbinding site for residue THP A 202
ChainResidue
ALYS84
ATYR85
AARG87
ALEU89
ATYR113
ATYR115
ALYS127
ACA201
AHOH301
AHOH305
AHOH310
AHOH320
AHOH323
AHOH329
AHOH335
AHOH346
AHOH350
AHOH358
AHOH364
AHOH369
AHOH372
AARG35
AASP40

Functional Information from PROSITE/UniProt
site_idPS01284
Number of Residues11
DetailsTNASE_2 Thermonuclease family signature 2. DKYGRgLAyIY
ChainResidueDetails
AASP83-TYR93

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:288045
ChainResidueDetails
AARG35
AGLU43
ATYR93

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING:
ChainResidueDetails
AASP21
AASP40
ATHR41

Catalytic Information from CSA
site_idMCSA1
Number of Residues6
DetailsM-CSA 165
ChainResidueDetails
AASP21metal ligand
AARG35electrostatic stabiliser, hydrogen bond donor
AASP40metal ligand
ATHR41metal ligand
AGLU43hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
ATYR93electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon