5CTE
Humanized yeast ACC carboxyltransferase domain bound to 2,2-dimethylpropyl (1S)-1-methyl-8-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,8-diazaspiro[4.5]decane-2-carboxylate
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 57L B 2301 |
| Chain | Residue |
| B | ARG1954 |
| B | GLU2032 |
| B | HOH2519 |
| C | LEU1762 |
| C | LYS1764 |
| C | VAL1765 |
| B | GLY1955 |
| B | PHE1956 |
| B | SER1957 |
| B | GLY1958 |
| B | LEU2025 |
| B | GLU2026 |
| B | GLU2028 |
| B | GLY2029 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 57L C 2301 |
| Chain | Residue |
| B | THR1757 |
| B | ALA1761 |
| B | LEU1762 |
| B | VAL1765 |
| C | ARG1954 |
| C | PHE1956 |
| C | SER1957 |
| C | GLY1958 |
| C | LEU2025 |
| C | GLU2026 |
| C | GLU2028 |
| C | GLY2029 |
| C | GLU2032 |
| C | HOH2660 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 2302 |
| Chain | Residue |
| C | ARG2154 |
| C | TRP2158 |
| C | LYS2185 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 336 |
| Details | Domain: {"description":"CoA carboxyltransferase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01136","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12663926","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26458104","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1OD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CSL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12663926","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1OD2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26458104","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5CSL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 315 |
| Details | Domain: {"description":"CoA carboxyltransferase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01137","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
