5CO4

Structural insights into the 2-OH methylation of C/U34 on tRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001510	biological_process	RNA methylation
A	0002130	biological_process	wobble position ribose methylation
A	0003723	molecular_function	RNA binding
A	0005737	cellular_component	cytoplasm
A	0006396	biological_process	RNA processing
A	0008033	biological_process	tRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008173	molecular_function	RNA methyltransferase activity
A	0008175	molecular_function	tRNA methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0030488	biological_process	tRNA methylation
A	0032259	biological_process	methylation
A	0141098	molecular_function	tRNA (cytidine(34)-2'-O)-methyltransferase activity
A	0141102	molecular_function	tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
B	0001510	biological_process	RNA methylation
B	0002130	biological_process	wobble position ribose methylation
B	0003723	molecular_function	RNA binding
B	0005737	cellular_component	cytoplasm
B	0006396	biological_process	RNA processing
B	0008033	biological_process	tRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0008173	molecular_function	RNA methyltransferase activity
B	0008175	molecular_function	tRNA methyltransferase activity
B	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
B	0016740	molecular_function	transferase activity
B	0030488	biological_process	tRNA methylation
B	0032259	biological_process	methylation
B	0141098	molecular_function	tRNA (cytidine(34)-2'-O)-methyltransferase activity
B	0141102	molecular_function	tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue MTA B 401

Chain	Residue
B	PHE79
B	ILE120
B	MET122
B	LEU129
B	ALA134
B	HOH567
B	SER80
B	ALA81
B	PHE100
B	GLY101
B	PRO102
B	GLU103
B	GLY106
B	LEU118

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site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 201

Chain	Residue
A	PHE79
A	SER80
A	ALA81
A	ARG82
A	GLY106
A	LEU107
A	MTA202
A	HOH310

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site_id	AC3
Number of Residues	14
Details	binding site for residue MTA A 202

Chain	Residue
A	PHE79
A	SER80
A	PHE100
A	GLY101
A	PRO102
A	GLU103
A	GLY106
A	LEU118
A	ILE120
A	MET122
A	LEU129
A	LEU131
A	ALA134
A	GOL201

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