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5CMD

Oligomer crystal structure of CC chemokine 5 (CCL5)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002407biological_processdendritic cell chemotaxis
A0002548biological_processmonocyte chemotaxis
A0002676biological_processregulation of chronic inflammatory response
A0004435molecular_functionphosphatidylinositol phospholipase C activity
A0004672molecular_functionprotein kinase activity
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0006816biological_processcalcium ion transport
A0006874biological_processintracellular calcium ion homeostasis
A0006887biological_processexocytosis
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007159biological_processleukocyte cell-cell adhesion
A0007186biological_processG protein-coupled receptor signaling pathway
A0007267biological_processcell-cell signaling
A0008009molecular_functionchemokine activity
A0009615biological_processresponse to virus
A0009636biological_processresponse to toxic substance
A0010536biological_processpositive regulation of activation of Janus kinase activity
A0010759biological_processpositive regulation of macrophage chemotaxis
A0010820biological_processpositive regulation of T cell chemotaxis
A0014911biological_processpositive regulation of smooth muscle cell migration
A0016004molecular_functionphospholipase activator activity
A0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
A0030335biological_processpositive regulation of cell migration
A0031328biological_processpositive regulation of cellular biosynthetic process
A0031584biological_processactivation of phospholipase D activity
A0031726molecular_functionCCR1 chemokine receptor binding
A0031729molecular_functionCCR4 chemokine receptor binding
A0031730molecular_functionCCR5 chemokine receptor binding
A0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
A0034097biological_processresponse to cytokine
A0034112biological_processpositive regulation of homotypic cell-cell adhesion
A0034612biological_processresponse to tumor necrosis factor
A0042056molecular_functionchemoattractant activity
A0042102biological_processpositive regulation of T cell proliferation
A0042119biological_processneutrophil activation
A0042327biological_processpositive regulation of phosphorylation
A0042379molecular_functionchemokine receptor binding
A0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043922biological_processnegative regulation by host of viral transcription
A0044344biological_processcellular response to fibroblast growth factor stimulus
A0045070biological_processpositive regulation of viral genome replication
A0045071biological_processnegative regulation of viral genome replication
A0045089biological_processpositive regulation of innate immune response
A0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
A0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
A0045785biological_processpositive regulation of cell adhesion
A0045948biological_processpositive regulation of translational initiation
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0046817molecular_functionchemokine receptor antagonist activity
A0048020molecular_functionCCR chemokine receptor binding
A0048245biological_processeosinophil chemotaxis
A0048246biological_processmacrophage chemotaxis
A0048661biological_processpositive regulation of smooth muscle cell proliferation
A0050673biological_processepithelial cell proliferation
A0050679biological_processpositive regulation of epithelial cell proliferation
A0050796biological_processregulation of insulin secretion
A0050863biological_processregulation of T cell activation
A0050918biological_processpositive chemotaxis
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0051928biological_processpositive regulation of calcium ion transport
A0060326biological_processcell chemotaxis
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070098biological_processchemokine-mediated signaling pathway
A0070100biological_processnegative regulation of chemokine-mediated signaling pathway
A0070233biological_processnegative regulation of T cell apoptotic process
A0070234biological_processpositive regulation of T cell apoptotic process
A0071346biological_processcellular response to type II interferon
A0071347biological_processcellular response to interleukin-1
A0071356biological_processcellular response to tumor necrosis factor
A0090026biological_processpositive regulation of monocyte chemotaxis
A0098586biological_processcellular response to virus
A2000110biological_processnegative regulation of macrophage apoptotic process
A2000406biological_processpositive regulation of T cell migration
A2000503biological_processpositive regulation of natural killer cell chemotaxis
B0002407biological_processdendritic cell chemotaxis
B0002548biological_processmonocyte chemotaxis
B0002676biological_processregulation of chronic inflammatory response
B0004435molecular_functionphosphatidylinositol phospholipase C activity
B0004672molecular_functionprotein kinase activity
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0006816biological_processcalcium ion transport
B0006874biological_processintracellular calcium ion homeostasis
B0006887biological_processexocytosis
B0006935biological_processchemotaxis
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007159biological_processleukocyte cell-cell adhesion
B0007186biological_processG protein-coupled receptor signaling pathway
B0007267biological_processcell-cell signaling
B0008009molecular_functionchemokine activity
B0009615biological_processresponse to virus
B0009636biological_processresponse to toxic substance
B0010536biological_processpositive regulation of activation of Janus kinase activity
B0010759biological_processpositive regulation of macrophage chemotaxis
B0010820biological_processpositive regulation of T cell chemotaxis
B0014911biological_processpositive regulation of smooth muscle cell migration
B0016004molecular_functionphospholipase activator activity
B0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
B0030335biological_processpositive regulation of cell migration
B0031328biological_processpositive regulation of cellular biosynthetic process
B0031584biological_processactivation of phospholipase D activity
B0031726molecular_functionCCR1 chemokine receptor binding
B0031729molecular_functionCCR4 chemokine receptor binding
B0031730molecular_functionCCR5 chemokine receptor binding
B0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
B0034097biological_processresponse to cytokine
B0034112biological_processpositive regulation of homotypic cell-cell adhesion
B0034612biological_processresponse to tumor necrosis factor
B0042056molecular_functionchemoattractant activity
B0042102biological_processpositive regulation of T cell proliferation
B0042119biological_processneutrophil activation
B0042327biological_processpositive regulation of phosphorylation
B0042379molecular_functionchemokine receptor binding
B0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043922biological_processnegative regulation by host of viral transcription
B0044344biological_processcellular response to fibroblast growth factor stimulus
B0045070biological_processpositive regulation of viral genome replication
B0045071biological_processnegative regulation of viral genome replication
B0045089biological_processpositive regulation of innate immune response
B0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
B0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
B0045785biological_processpositive regulation of cell adhesion
B0045948biological_processpositive regulation of translational initiation
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046817molecular_functionchemokine receptor antagonist activity
B0048020molecular_functionCCR chemokine receptor binding
B0048245biological_processeosinophil chemotaxis
B0048246biological_processmacrophage chemotaxis
B0048661biological_processpositive regulation of smooth muscle cell proliferation
B0050673biological_processepithelial cell proliferation
B0050679biological_processpositive regulation of epithelial cell proliferation
B0050796biological_processregulation of insulin secretion
B0050863biological_processregulation of T cell activation
B0050918biological_processpositive chemotaxis
B0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B0051928biological_processpositive regulation of calcium ion transport
B0060326biological_processcell chemotaxis
B0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0070098biological_processchemokine-mediated signaling pathway
B0070100biological_processnegative regulation of chemokine-mediated signaling pathway
B0070233biological_processnegative regulation of T cell apoptotic process
B0070234biological_processpositive regulation of T cell apoptotic process
B0071346biological_processcellular response to type II interferon
B0071347biological_processcellular response to interleukin-1
B0071356biological_processcellular response to tumor necrosis factor
B0090026biological_processpositive regulation of monocyte chemotaxis
B0098586biological_processcellular response to virus
B2000110biological_processnegative regulation of macrophage apoptotic process
B2000406biological_processpositive regulation of T cell migration
B2000503biological_processpositive regulation of natural killer cell chemotaxis
C0002407biological_processdendritic cell chemotaxis
C0002548biological_processmonocyte chemotaxis
C0002676biological_processregulation of chronic inflammatory response
C0004435molecular_functionphosphatidylinositol phospholipase C activity
C0004672molecular_functionprotein kinase activity
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005737cellular_componentcytoplasm
C0006816biological_processcalcium ion transport
C0006874biological_processintracellular calcium ion homeostasis
C0006887biological_processexocytosis
C0006935biological_processchemotaxis
C0006954biological_processinflammatory response
C0006955biological_processimmune response
C0007159biological_processleukocyte cell-cell adhesion
C0007186biological_processG protein-coupled receptor signaling pathway
C0007267biological_processcell-cell signaling
C0008009molecular_functionchemokine activity
C0009615biological_processresponse to virus
C0009636biological_processresponse to toxic substance
C0010536biological_processpositive regulation of activation of Janus kinase activity
C0010759biological_processpositive regulation of macrophage chemotaxis
C0010820biological_processpositive regulation of T cell chemotaxis
C0014911biological_processpositive regulation of smooth muscle cell migration
C0016004molecular_functionphospholipase activator activity
C0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
C0030335biological_processpositive regulation of cell migration
C0031328biological_processpositive regulation of cellular biosynthetic process
C0031584biological_processactivation of phospholipase D activity
C0031726molecular_functionCCR1 chemokine receptor binding
C0031729molecular_functionCCR4 chemokine receptor binding
C0031730molecular_functionCCR5 chemokine receptor binding
C0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
C0034097biological_processresponse to cytokine
C0034112biological_processpositive regulation of homotypic cell-cell adhesion
C0034612biological_processresponse to tumor necrosis factor
C0042056molecular_functionchemoattractant activity
C0042102biological_processpositive regulation of T cell proliferation
C0042119biological_processneutrophil activation
C0042327biological_processpositive regulation of phosphorylation
C0042379molecular_functionchemokine receptor binding
C0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043922biological_processnegative regulation by host of viral transcription
C0044344biological_processcellular response to fibroblast growth factor stimulus
C0045070biological_processpositive regulation of viral genome replication
C0045071biological_processnegative regulation of viral genome replication
C0045089biological_processpositive regulation of innate immune response
C0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
C0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
C0045785biological_processpositive regulation of cell adhesion
C0045948biological_processpositive regulation of translational initiation
C0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
C0046817molecular_functionchemokine receptor antagonist activity
C0048020molecular_functionCCR chemokine receptor binding
C0048245biological_processeosinophil chemotaxis
C0048246biological_processmacrophage chemotaxis
C0048661biological_processpositive regulation of smooth muscle cell proliferation
C0050673biological_processepithelial cell proliferation
C0050679biological_processpositive regulation of epithelial cell proliferation
C0050796biological_processregulation of insulin secretion
C0050863biological_processregulation of T cell activation
C0050918biological_processpositive chemotaxis
C0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C0051928biological_processpositive regulation of calcium ion transport
C0060326biological_processcell chemotaxis
C0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
C0070098biological_processchemokine-mediated signaling pathway
C0070100biological_processnegative regulation of chemokine-mediated signaling pathway
C0070233biological_processnegative regulation of T cell apoptotic process
C0070234biological_processpositive regulation of T cell apoptotic process
C0071346biological_processcellular response to type II interferon
C0071347biological_processcellular response to interleukin-1
C0071356biological_processcellular response to tumor necrosis factor
C0090026biological_processpositive regulation of monocyte chemotaxis
C0098586biological_processcellular response to virus
C2000110biological_processnegative regulation of macrophage apoptotic process
C2000406biological_processpositive regulation of T cell migration
C2000503biological_processpositive regulation of natural killer cell chemotaxis
D0002407biological_processdendritic cell chemotaxis
D0002548biological_processmonocyte chemotaxis
D0002676biological_processregulation of chronic inflammatory response
D0004435molecular_functionphosphatidylinositol phospholipase C activity
D0004672molecular_functionprotein kinase activity
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005737cellular_componentcytoplasm
D0006816biological_processcalcium ion transport
D0006874biological_processintracellular calcium ion homeostasis
D0006887biological_processexocytosis
D0006935biological_processchemotaxis
D0006954biological_processinflammatory response
D0006955biological_processimmune response
D0007159biological_processleukocyte cell-cell adhesion
D0007186biological_processG protein-coupled receptor signaling pathway
D0007267biological_processcell-cell signaling
D0008009molecular_functionchemokine activity
D0009615biological_processresponse to virus
D0009636biological_processresponse to toxic substance
D0010536biological_processpositive regulation of activation of Janus kinase activity
D0010759biological_processpositive regulation of macrophage chemotaxis
D0010820biological_processpositive regulation of T cell chemotaxis
D0014911biological_processpositive regulation of smooth muscle cell migration
D0016004molecular_functionphospholipase activator activity
D0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
D0030335biological_processpositive regulation of cell migration
D0031328biological_processpositive regulation of cellular biosynthetic process
D0031584biological_processactivation of phospholipase D activity
D0031726molecular_functionCCR1 chemokine receptor binding
D0031729molecular_functionCCR4 chemokine receptor binding
D0031730molecular_functionCCR5 chemokine receptor binding
D0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
D0034097biological_processresponse to cytokine
D0034112biological_processpositive regulation of homotypic cell-cell adhesion
D0034612biological_processresponse to tumor necrosis factor
D0042056molecular_functionchemoattractant activity
D0042102biological_processpositive regulation of T cell proliferation
D0042119biological_processneutrophil activation
D0042327biological_processpositive regulation of phosphorylation
D0042379molecular_functionchemokine receptor binding
D0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043922biological_processnegative regulation by host of viral transcription
D0044344biological_processcellular response to fibroblast growth factor stimulus
D0045070biological_processpositive regulation of viral genome replication
D0045071biological_processnegative regulation of viral genome replication
D0045089biological_processpositive regulation of innate immune response
D0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
D0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
D0045785biological_processpositive regulation of cell adhesion
D0045948biological_processpositive regulation of translational initiation
D0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
D0046817molecular_functionchemokine receptor antagonist activity
D0048020molecular_functionCCR chemokine receptor binding
D0048245biological_processeosinophil chemotaxis
D0048246biological_processmacrophage chemotaxis
D0048661biological_processpositive regulation of smooth muscle cell proliferation
D0050673biological_processepithelial cell proliferation
D0050679biological_processpositive regulation of epithelial cell proliferation
D0050796biological_processregulation of insulin secretion
D0050863biological_processregulation of T cell activation
D0050918biological_processpositive chemotaxis
D0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
D0051928biological_processpositive regulation of calcium ion transport
D0060326biological_processcell chemotaxis
D0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
D0070098biological_processchemokine-mediated signaling pathway
D0070100biological_processnegative regulation of chemokine-mediated signaling pathway
D0070233biological_processnegative regulation of T cell apoptotic process
D0070234biological_processpositive regulation of T cell apoptotic process
D0071346biological_processcellular response to type II interferon
D0071347biological_processcellular response to interleukin-1
D0071356biological_processcellular response to tumor necrosis factor
D0090026biological_processpositive regulation of monocyte chemotaxis
D0098586biological_processcellular response to virus
D2000110biological_processnegative regulation of macrophage apoptotic process
D2000406biological_processpositive regulation of T cell migration
D2000503biological_processpositive regulation of natural killer cell chemotaxis
E0002407biological_processdendritic cell chemotaxis
E0002548biological_processmonocyte chemotaxis
E0002676biological_processregulation of chronic inflammatory response
E0004435molecular_functionphosphatidylinositol phospholipase C activity
E0004672molecular_functionprotein kinase activity
E0005125molecular_functioncytokine activity
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005737cellular_componentcytoplasm
E0006816biological_processcalcium ion transport
E0006874biological_processintracellular calcium ion homeostasis
E0006887biological_processexocytosis
E0006935biological_processchemotaxis
E0006954biological_processinflammatory response
E0006955biological_processimmune response
E0007159biological_processleukocyte cell-cell adhesion
E0007186biological_processG protein-coupled receptor signaling pathway
E0007267biological_processcell-cell signaling
E0008009molecular_functionchemokine activity
E0009615biological_processresponse to virus
E0009636biological_processresponse to toxic substance
E0010536biological_processpositive regulation of activation of Janus kinase activity
E0010759biological_processpositive regulation of macrophage chemotaxis
E0010820biological_processpositive regulation of T cell chemotaxis
E0014911biological_processpositive regulation of smooth muscle cell migration
E0016004molecular_functionphospholipase activator activity
E0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
E0030335biological_processpositive regulation of cell migration
E0031328biological_processpositive regulation of cellular biosynthetic process
E0031584biological_processactivation of phospholipase D activity
E0031726molecular_functionCCR1 chemokine receptor binding
E0031729molecular_functionCCR4 chemokine receptor binding
E0031730molecular_functionCCR5 chemokine receptor binding
E0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
E0034097biological_processresponse to cytokine
E0034112biological_processpositive regulation of homotypic cell-cell adhesion
E0034612biological_processresponse to tumor necrosis factor
E0042056molecular_functionchemoattractant activity
E0042102biological_processpositive regulation of T cell proliferation
E0042119biological_processneutrophil activation
E0042327biological_processpositive regulation of phosphorylation
E0042379molecular_functionchemokine receptor binding
E0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0043922biological_processnegative regulation by host of viral transcription
E0044344biological_processcellular response to fibroblast growth factor stimulus
E0045070biological_processpositive regulation of viral genome replication
E0045071biological_processnegative regulation of viral genome replication
E0045089biological_processpositive regulation of innate immune response
E0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
E0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
E0045785biological_processpositive regulation of cell adhesion
E0045948biological_processpositive regulation of translational initiation
E0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
E0046817molecular_functionchemokine receptor antagonist activity
E0048020molecular_functionCCR chemokine receptor binding
E0048245biological_processeosinophil chemotaxis
E0048246biological_processmacrophage chemotaxis
E0048661biological_processpositive regulation of smooth muscle cell proliferation
E0050673biological_processepithelial cell proliferation
E0050679biological_processpositive regulation of epithelial cell proliferation
E0050796biological_processregulation of insulin secretion
E0050863biological_processregulation of T cell activation
E0050918biological_processpositive chemotaxis
E0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E0051928biological_processpositive regulation of calcium ion transport
E0060326biological_processcell chemotaxis
E0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
E0070098biological_processchemokine-mediated signaling pathway
E0070100biological_processnegative regulation of chemokine-mediated signaling pathway
E0070233biological_processnegative regulation of T cell apoptotic process
E0070234biological_processpositive regulation of T cell apoptotic process
E0071346biological_processcellular response to type II interferon
E0071347biological_processcellular response to interleukin-1
E0071356biological_processcellular response to tumor necrosis factor
E0090026biological_processpositive regulation of monocyte chemotaxis
E0098586biological_processcellular response to virus
E2000110biological_processnegative regulation of macrophage apoptotic process
E2000406biological_processpositive regulation of T cell migration
E2000503biological_processpositive regulation of natural killer cell chemotaxis
F0002407biological_processdendritic cell chemotaxis
F0002548biological_processmonocyte chemotaxis
F0002676biological_processregulation of chronic inflammatory response
F0004435molecular_functionphosphatidylinositol phospholipase C activity
F0004672molecular_functionprotein kinase activity
F0005125molecular_functioncytokine activity
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005737cellular_componentcytoplasm
F0006816biological_processcalcium ion transport
F0006874biological_processintracellular calcium ion homeostasis
F0006887biological_processexocytosis
F0006935biological_processchemotaxis
F0006954biological_processinflammatory response
F0006955biological_processimmune response
F0007159biological_processleukocyte cell-cell adhesion
F0007186biological_processG protein-coupled receptor signaling pathway
F0007267biological_processcell-cell signaling
F0008009molecular_functionchemokine activity
F0009615biological_processresponse to virus
F0009636biological_processresponse to toxic substance
F0010536biological_processpositive regulation of activation of Janus kinase activity
F0010759biological_processpositive regulation of macrophage chemotaxis
F0010820biological_processpositive regulation of T cell chemotaxis
F0014911biological_processpositive regulation of smooth muscle cell migration
F0016004molecular_functionphospholipase activator activity
F0030298molecular_functionreceptor signaling protein tyrosine kinase activator activity
F0030335biological_processpositive regulation of cell migration
F0031328biological_processpositive regulation of cellular biosynthetic process
F0031584biological_processactivation of phospholipase D activity
F0031726molecular_functionCCR1 chemokine receptor binding
F0031729molecular_functionCCR4 chemokine receptor binding
F0031730molecular_functionCCR5 chemokine receptor binding
F0033634biological_processpositive regulation of cell-cell adhesion mediated by integrin
F0034097biological_processresponse to cytokine
F0034112biological_processpositive regulation of homotypic cell-cell adhesion
F0034612biological_processresponse to tumor necrosis factor
F0042056molecular_functionchemoattractant activity
F0042102biological_processpositive regulation of T cell proliferation
F0042119biological_processneutrophil activation
F0042327biological_processpositive regulation of phosphorylation
F0042379molecular_functionchemokine receptor binding
F0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0043922biological_processnegative regulation by host of viral transcription
F0044344biological_processcellular response to fibroblast growth factor stimulus
F0045070biological_processpositive regulation of viral genome replication
F0045071biological_processnegative regulation of viral genome replication
F0045089biological_processpositive regulation of innate immune response
F0045744biological_processnegative regulation of G protein-coupled receptor signaling pathway
F0045745biological_processpositive regulation of G protein-coupled receptor signaling pathway
F0045785biological_processpositive regulation of cell adhesion
F0045948biological_processpositive regulation of translational initiation
F0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
F0046817molecular_functionchemokine receptor antagonist activity
F0048020molecular_functionCCR chemokine receptor binding
F0048245biological_processeosinophil chemotaxis
F0048246biological_processmacrophage chemotaxis
F0048661biological_processpositive regulation of smooth muscle cell proliferation
F0050673biological_processepithelial cell proliferation
F0050679biological_processpositive regulation of epithelial cell proliferation
F0050796biological_processregulation of insulin secretion
F0050863biological_processregulation of T cell activation
F0050918biological_processpositive chemotaxis
F0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
F0051928biological_processpositive regulation of calcium ion transport
F0060326biological_processcell chemotaxis
F0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
F0070098biological_processchemokine-mediated signaling pathway
F0070100biological_processnegative regulation of chemokine-mediated signaling pathway
F0070233biological_processnegative regulation of T cell apoptotic process
F0070234biological_processpositive regulation of T cell apoptotic process
F0071346biological_processcellular response to type II interferon
F0071347biological_processcellular response to interleukin-1
F0071356biological_processcellular response to tumor necrosis factor
F0090026biological_processpositive regulation of monocyte chemotaxis
F0098586biological_processcellular response to virus
F2000110biological_processnegative regulation of macrophage apoptotic process
F2000406biological_processpositive regulation of T cell migration
F2000503biological_processpositive regulation of natural killer cell chemotaxis
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue SO4 A 103
ChainResidue
ASER31
AGLY32

site_idAC2
Number of Residues3
Detailsbinding site for residue SO4 A 104
ChainResidue
ALYS56
AARG59
FLYS56

site_idAC3
Number of Residues2
Detailsbinding site for residue SO4 B 101
ChainResidue
BLYS55
BLYS56

site_idAC4
Number of Residues1
Detailsbinding site for residue SO4 B 102
ChainResidue
BARG17

site_idAC5
Number of Residues2
Detailsbinding site for residue SO4 C 101
ChainResidue
CLYS56
CLYS55

site_idAC6
Number of Residues2
Detailsbinding site for residue SO4 E 101
ChainResidue
ELYS55
ELYS56

site_idAC7
Number of Residues2
Detailsbinding site for residue SO4 F 101
ChainResidue
FLYS55
FLYS56

Functional Information from PROSITE/UniProt
site_idPS00472
Number of Residues42
DetailsSMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFayiarp..LprahIkeYfytsgk..Csnp.AVVFvtrknrqv.CA
ChainResidueDetails
ACYS10-ALA51

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsMOD_RES: Methionine sulfoxide => ECO:0000269|PubMed:1380064
ChainResidueDetails
AMET67
BMET67
CMET67
DMET67
EMET67
FMET67

site_idSWS_FT_FI2
Number of Residues12
DetailsCARBOHYD: O-linked (GalNAc...) serine; partial => ECO:0000269|PubMed:1380064
ChainResidueDetails
ASER4
ASER5
BSER4
BSER5
CSER4
CSER5
DSER4
DSER5
ESER4
ESER5
FSER4
FSER5

221051

PDB entries from 2024-06-12

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