5CJ2

Ran GDP Y39A mutant triclinic crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000054	biological_process	ribosomal subunit export from nucleus
A	0000055	biological_process	ribosomal large subunit export from nucleus
A	0000056	biological_process	ribosomal small subunit export from nucleus
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000278	biological_process	mitotic cell cycle
A	0000287	molecular_function	magnesium ion binding
A	0000785	cellular_component	chromatin
A	0001673	cellular_component	male germ cell nucleus
A	0002177	cellular_component	manchette
A	0003682	molecular_function	chromatin binding
A	0003723	molecular_function	RNA binding
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005049	molecular_function	nuclear export signal receptor activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005643	cellular_component	nuclear pore
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005814	cellular_component	centriole
A	0005829	cellular_component	cytosol
A	0006259	biological_process	DNA metabolic process
A	0006606	biological_process	protein import into nucleus
A	0006611	biological_process	protein export from nucleus
A	0006913	biological_process	nucleocytoplasmic transport
A	0007052	biological_process	mitotic spindle organization
A	0007286	biological_process	spermatid development
A	0008104	biological_process	protein localization
A	0014070	biological_process	response to organic cyclic compound
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016032	biological_process	viral process
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0019904	molecular_function	protein domain specific binding
A	0021766	biological_process	hippocampus development
A	0030036	biological_process	actin cytoskeleton organization
A	0030496	cellular_component	midbody
A	0031503	biological_process	protein-containing complex localization
A	0032092	biological_process	positive regulation of protein binding
A	0032991	cellular_component	protein-containing complex
A	0035281	biological_process	pre-miRNA export from nucleus
A	0036126	cellular_component	sperm flagellum
A	0042307	biological_process	positive regulation of protein import into nucleus
A	0042470	cellular_component	melanosome
A	0042565	cellular_component	RNA nuclear export complex
A	0044877	molecular_function	protein-containing complex binding
A	0045296	molecular_function	cadherin binding
A	0045505	molecular_function	dynein intermediate chain binding
A	0046039	biological_process	GTP metabolic process
A	0046872	molecular_function	metal ion binding
A	0046982	molecular_function	protein heterodimerization activity
A	0051301	biological_process	cell division
A	0055037	cellular_component	recycling endosome
A	0061015	biological_process	snRNA import into nucleus
A	0061676	molecular_function	importin-alpha family protein binding
A	0070062	cellular_component	extracellular exosome
A	0070883	molecular_function	pre-miRNA binding
A	0071389	biological_process	cellular response to mineralocorticoid stimulus
A	0090543	cellular_component	Flemming body
A	1902570	biological_process	protein localization to nucleolus
B	0000054	biological_process	ribosomal subunit export from nucleus
B	0000055	biological_process	ribosomal large subunit export from nucleus
B	0000056	biological_process	ribosomal small subunit export from nucleus
B	0000070	biological_process	mitotic sister chromatid segregation
B	0000278	biological_process	mitotic cell cycle
B	0000287	molecular_function	magnesium ion binding
B	0000785	cellular_component	chromatin
B	0001673	cellular_component	male germ cell nucleus
B	0002177	cellular_component	manchette
B	0003682	molecular_function	chromatin binding
B	0003723	molecular_function	RNA binding
B	0003924	molecular_function	GTPase activity
B	0003925	molecular_function	G protein activity
B	0005049	molecular_function	nuclear export signal receptor activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005643	cellular_component	nuclear pore
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005814	cellular_component	centriole
B	0005829	cellular_component	cytosol
B	0006259	biological_process	DNA metabolic process
B	0006606	biological_process	protein import into nucleus
B	0006611	biological_process	protein export from nucleus
B	0006913	biological_process	nucleocytoplasmic transport
B	0007052	biological_process	mitotic spindle organization
B	0007286	biological_process	spermatid development
B	0008104	biological_process	protein localization
B	0014070	biological_process	response to organic cyclic compound
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016032	biological_process	viral process
B	0016787	molecular_function	hydrolase activity
B	0019003	molecular_function	GDP binding
B	0019904	molecular_function	protein domain specific binding
B	0021766	biological_process	hippocampus development
B	0030036	biological_process	actin cytoskeleton organization
B	0030496	cellular_component	midbody
B	0031503	biological_process	protein-containing complex localization
B	0032092	biological_process	positive regulation of protein binding
B	0032991	cellular_component	protein-containing complex
B	0035281	biological_process	pre-miRNA export from nucleus
B	0036126	cellular_component	sperm flagellum
B	0042307	biological_process	positive regulation of protein import into nucleus
B	0042470	cellular_component	melanosome
B	0042565	cellular_component	RNA nuclear export complex
B	0044877	molecular_function	protein-containing complex binding
B	0045296	molecular_function	cadherin binding
B	0045505	molecular_function	dynein intermediate chain binding
B	0046039	biological_process	GTP metabolic process
B	0046872	molecular_function	metal ion binding
B	0046982	molecular_function	protein heterodimerization activity
B	0051301	biological_process	cell division
B	0055037	cellular_component	recycling endosome
B	0061015	biological_process	snRNA import into nucleus
B	0061676	molecular_function	importin-alpha family protein binding
B	0070062	cellular_component	extracellular exosome
B	0070883	molecular_function	pre-miRNA binding
B	0071389	biological_process	cellular response to mineralocorticoid stimulus
B	0090543	cellular_component	Flemming body
B	1902570	biological_process	protein localization to nucleolus
C	0000054	biological_process	ribosomal subunit export from nucleus
C	0000055	biological_process	ribosomal large subunit export from nucleus
C	0000056	biological_process	ribosomal small subunit export from nucleus
C	0000070	biological_process	mitotic sister chromatid segregation
C	0000278	biological_process	mitotic cell cycle
C	0000287	molecular_function	magnesium ion binding
C	0000785	cellular_component	chromatin
C	0001673	cellular_component	male germ cell nucleus
C	0002177	cellular_component	manchette
C	0003682	molecular_function	chromatin binding
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0003925	molecular_function	G protein activity
C	0005049	molecular_function	nuclear export signal receptor activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005643	cellular_component	nuclear pore
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005814	cellular_component	centriole
C	0005829	cellular_component	cytosol
C	0006259	biological_process	DNA metabolic process
C	0006606	biological_process	protein import into nucleus
C	0006611	biological_process	protein export from nucleus
C	0006913	biological_process	nucleocytoplasmic transport
C	0007052	biological_process	mitotic spindle organization
C	0007286	biological_process	spermatid development
C	0008104	biological_process	protein localization
C	0014070	biological_process	response to organic cyclic compound
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016032	biological_process	viral process
C	0016787	molecular_function	hydrolase activity
C	0019003	molecular_function	GDP binding
C	0019904	molecular_function	protein domain specific binding
C	0021766	biological_process	hippocampus development
C	0030036	biological_process	actin cytoskeleton organization
C	0030496	cellular_component	midbody
C	0031503	biological_process	protein-containing complex localization
C	0032092	biological_process	positive regulation of protein binding
C	0032991	cellular_component	protein-containing complex
C	0035281	biological_process	pre-miRNA export from nucleus
C	0036126	cellular_component	sperm flagellum
C	0042307	biological_process	positive regulation of protein import into nucleus
C	0042470	cellular_component	melanosome
C	0042565	cellular_component	RNA nuclear export complex
C	0044877	molecular_function	protein-containing complex binding
C	0045296	molecular_function	cadherin binding
C	0045505	molecular_function	dynein intermediate chain binding
C	0046039	biological_process	GTP metabolic process
C	0046872	molecular_function	metal ion binding
C	0046982	molecular_function	protein heterodimerization activity
C	0051301	biological_process	cell division
C	0055037	cellular_component	recycling endosome
C	0061015	biological_process	snRNA import into nucleus
C	0061676	molecular_function	importin-alpha family protein binding
C	0070062	cellular_component	extracellular exosome
C	0070883	molecular_function	pre-miRNA binding
C	0071389	biological_process	cellular response to mineralocorticoid stimulus
C	0090543	cellular_component	Flemming body
C	1902570	biological_process	protein localization to nucleolus
D	0000054	biological_process	ribosomal subunit export from nucleus
D	0000055	biological_process	ribosomal large subunit export from nucleus
D	0000056	biological_process	ribosomal small subunit export from nucleus
D	0000070	biological_process	mitotic sister chromatid segregation
D	0000278	biological_process	mitotic cell cycle
D	0000287	molecular_function	magnesium ion binding
D	0000785	cellular_component	chromatin
D	0001673	cellular_component	male germ cell nucleus
D	0002177	cellular_component	manchette
D	0003682	molecular_function	chromatin binding
D	0003723	molecular_function	RNA binding
D	0003924	molecular_function	GTPase activity
D	0003925	molecular_function	G protein activity
D	0005049	molecular_function	nuclear export signal receptor activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005643	cellular_component	nuclear pore
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005814	cellular_component	centriole
D	0005829	cellular_component	cytosol
D	0006259	biological_process	DNA metabolic process
D	0006606	biological_process	protein import into nucleus
D	0006611	biological_process	protein export from nucleus
D	0006913	biological_process	nucleocytoplasmic transport
D	0007052	biological_process	mitotic spindle organization
D	0007286	biological_process	spermatid development
D	0008104	biological_process	protein localization
D	0014070	biological_process	response to organic cyclic compound
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0016032	biological_process	viral process
D	0016787	molecular_function	hydrolase activity
D	0019003	molecular_function	GDP binding
D	0019904	molecular_function	protein domain specific binding
D	0021766	biological_process	hippocampus development
D	0030036	biological_process	actin cytoskeleton organization
D	0030496	cellular_component	midbody
D	0031503	biological_process	protein-containing complex localization
D	0032092	biological_process	positive regulation of protein binding
D	0032991	cellular_component	protein-containing complex
D	0035281	biological_process	pre-miRNA export from nucleus
D	0036126	cellular_component	sperm flagellum
D	0042307	biological_process	positive regulation of protein import into nucleus
D	0042470	cellular_component	melanosome
D	0042565	cellular_component	RNA nuclear export complex
D	0044877	molecular_function	protein-containing complex binding
D	0045296	molecular_function	cadherin binding
D	0045505	molecular_function	dynein intermediate chain binding
D	0046039	biological_process	GTP metabolic process
D	0046872	molecular_function	metal ion binding
D	0046982	molecular_function	protein heterodimerization activity
D	0051301	biological_process	cell division
D	0055037	cellular_component	recycling endosome
D	0061015	biological_process	snRNA import into nucleus
D	0061676	molecular_function	importin-alpha family protein binding
D	0070062	cellular_component	extracellular exosome
D	0070883	molecular_function	pre-miRNA binding
D	0071389	biological_process	cellular response to mineralocorticoid stimulus
D	0090543	cellular_component	Flemming body
D	1902570	biological_process	protein localization to nucleolus
E	0000054	biological_process	ribosomal subunit export from nucleus
E	0000055	biological_process	ribosomal large subunit export from nucleus
E	0000056	biological_process	ribosomal small subunit export from nucleus
E	0000070	biological_process	mitotic sister chromatid segregation
E	0000278	biological_process	mitotic cell cycle
E	0000287	molecular_function	magnesium ion binding
E	0000785	cellular_component	chromatin
E	0001673	cellular_component	male germ cell nucleus
E	0002177	cellular_component	manchette
E	0003682	molecular_function	chromatin binding
E	0003723	molecular_function	RNA binding
E	0003924	molecular_function	GTPase activity
E	0003925	molecular_function	G protein activity
E	0005049	molecular_function	nuclear export signal receptor activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005634	cellular_component	nucleus
E	0005635	cellular_component	nuclear envelope
E	0005643	cellular_component	nuclear pore
E	0005654	cellular_component	nucleoplasm
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005814	cellular_component	centriole
E	0005829	cellular_component	cytosol
E	0006259	biological_process	DNA metabolic process
E	0006606	biological_process	protein import into nucleus
E	0006611	biological_process	protein export from nucleus
E	0006913	biological_process	nucleocytoplasmic transport
E	0007052	biological_process	mitotic spindle organization
E	0007286	biological_process	spermatid development
E	0008104	biological_process	protein localization
E	0014070	biological_process	response to organic cyclic compound
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0016032	biological_process	viral process
E	0016787	molecular_function	hydrolase activity
E	0019003	molecular_function	GDP binding
E	0019904	molecular_function	protein domain specific binding
E	0021766	biological_process	hippocampus development
E	0030036	biological_process	actin cytoskeleton organization
E	0030496	cellular_component	midbody
E	0031503	biological_process	protein-containing complex localization
E	0032092	biological_process	positive regulation of protein binding
E	0032991	cellular_component	protein-containing complex
E	0035281	biological_process	pre-miRNA export from nucleus
E	0036126	cellular_component	sperm flagellum
E	0042307	biological_process	positive regulation of protein import into nucleus
E	0042470	cellular_component	melanosome
E	0042565	cellular_component	RNA nuclear export complex
E	0044877	molecular_function	protein-containing complex binding
E	0045296	molecular_function	cadherin binding
E	0045505	molecular_function	dynein intermediate chain binding
E	0046039	biological_process	GTP metabolic process
E	0046872	molecular_function	metal ion binding
E	0046982	molecular_function	protein heterodimerization activity
E	0051301	biological_process	cell division
E	0055037	cellular_component	recycling endosome
E	0061015	biological_process	snRNA import into nucleus
E	0061676	molecular_function	importin-alpha family protein binding
E	0070062	cellular_component	extracellular exosome
E	0070883	molecular_function	pre-miRNA binding
E	0071389	biological_process	cellular response to mineralocorticoid stimulus
E	0090543	cellular_component	Flemming body
E	1902570	biological_process	protein localization to nucleolus
F	0000054	biological_process	ribosomal subunit export from nucleus
F	0000055	biological_process	ribosomal large subunit export from nucleus
F	0000056	biological_process	ribosomal small subunit export from nucleus
F	0000070	biological_process	mitotic sister chromatid segregation
F	0000278	biological_process	mitotic cell cycle
F	0000287	molecular_function	magnesium ion binding
F	0000785	cellular_component	chromatin
F	0001673	cellular_component	male germ cell nucleus
F	0002177	cellular_component	manchette
F	0003682	molecular_function	chromatin binding
F	0003723	molecular_function	RNA binding
F	0003924	molecular_function	GTPase activity
F	0003925	molecular_function	G protein activity
F	0005049	molecular_function	nuclear export signal receptor activity
F	0005515	molecular_function	protein binding
F	0005525	molecular_function	GTP binding
F	0005634	cellular_component	nucleus
F	0005635	cellular_component	nuclear envelope
F	0005643	cellular_component	nuclear pore
F	0005654	cellular_component	nucleoplasm
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005814	cellular_component	centriole
F	0005829	cellular_component	cytosol
F	0006259	biological_process	DNA metabolic process
F	0006606	biological_process	protein import into nucleus
F	0006611	biological_process	protein export from nucleus
F	0006913	biological_process	nucleocytoplasmic transport
F	0007052	biological_process	mitotic spindle organization
F	0007286	biological_process	spermatid development
F	0008104	biological_process	protein localization
F	0014070	biological_process	response to organic cyclic compound
F	0015031	biological_process	protein transport
F	0016020	cellular_component	membrane
F	0016032	biological_process	viral process
F	0016787	molecular_function	hydrolase activity
F	0019003	molecular_function	GDP binding
F	0019904	molecular_function	protein domain specific binding
F	0021766	biological_process	hippocampus development
F	0030036	biological_process	actin cytoskeleton organization
F	0030496	cellular_component	midbody
F	0031503	biological_process	protein-containing complex localization
F	0032092	biological_process	positive regulation of protein binding
F	0032991	cellular_component	protein-containing complex
F	0035281	biological_process	pre-miRNA export from nucleus
F	0036126	cellular_component	sperm flagellum
F	0042307	biological_process	positive regulation of protein import into nucleus
F	0042470	cellular_component	melanosome
F	0042565	cellular_component	RNA nuclear export complex
F	0044877	molecular_function	protein-containing complex binding
F	0045296	molecular_function	cadherin binding
F	0045505	molecular_function	dynein intermediate chain binding
F	0046039	biological_process	GTP metabolic process
F	0046872	molecular_function	metal ion binding
F	0046982	molecular_function	protein heterodimerization activity
F	0051301	biological_process	cell division
F	0055037	cellular_component	recycling endosome
F	0061015	biological_process	snRNA import into nucleus
F	0061676	molecular_function	importin-alpha family protein binding
F	0070062	cellular_component	extracellular exosome
F	0070883	molecular_function	pre-miRNA binding
F	0071389	biological_process	cellular response to mineralocorticoid stimulus
F	0090543	cellular_component	Flemming body
F	1902570	biological_process	protein localization to nucleolus
G	0000054	biological_process	ribosomal subunit export from nucleus
G	0000055	biological_process	ribosomal large subunit export from nucleus
G	0000056	biological_process	ribosomal small subunit export from nucleus
G	0000070	biological_process	mitotic sister chromatid segregation
G	0000278	biological_process	mitotic cell cycle
G	0000287	molecular_function	magnesium ion binding
G	0000785	cellular_component	chromatin
G	0001673	cellular_component	male germ cell nucleus
G	0002177	cellular_component	manchette
G	0003682	molecular_function	chromatin binding
G	0003723	molecular_function	RNA binding
G	0003924	molecular_function	GTPase activity
G	0003925	molecular_function	G protein activity
G	0005049	molecular_function	nuclear export signal receptor activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005634	cellular_component	nucleus
G	0005635	cellular_component	nuclear envelope
G	0005643	cellular_component	nuclear pore
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005814	cellular_component	centriole
G	0005829	cellular_component	cytosol
G	0006259	biological_process	DNA metabolic process
G	0006606	biological_process	protein import into nucleus
G	0006611	biological_process	protein export from nucleus
G	0006913	biological_process	nucleocytoplasmic transport
G	0007052	biological_process	mitotic spindle organization
G	0007286	biological_process	spermatid development
G	0008104	biological_process	protein localization
G	0014070	biological_process	response to organic cyclic compound
G	0015031	biological_process	protein transport
G	0016020	cellular_component	membrane
G	0016032	biological_process	viral process
G	0016787	molecular_function	hydrolase activity
G	0019003	molecular_function	GDP binding
G	0019904	molecular_function	protein domain specific binding
G	0021766	biological_process	hippocampus development
G	0030036	biological_process	actin cytoskeleton organization
G	0030496	cellular_component	midbody
G	0031503	biological_process	protein-containing complex localization
G	0032092	biological_process	positive regulation of protein binding
G	0032991	cellular_component	protein-containing complex
G	0035281	biological_process	pre-miRNA export from nucleus
G	0036126	cellular_component	sperm flagellum
G	0042307	biological_process	positive regulation of protein import into nucleus
G	0042470	cellular_component	melanosome
G	0042565	cellular_component	RNA nuclear export complex
G	0044877	molecular_function	protein-containing complex binding
G	0045296	molecular_function	cadherin binding
G	0045505	molecular_function	dynein intermediate chain binding
G	0046039	biological_process	GTP metabolic process
G	0046872	molecular_function	metal ion binding
G	0046982	molecular_function	protein heterodimerization activity
G	0051301	biological_process	cell division
G	0055037	cellular_component	recycling endosome
G	0061015	biological_process	snRNA import into nucleus
G	0061676	molecular_function	importin-alpha family protein binding
G	0070062	cellular_component	extracellular exosome
G	0070883	molecular_function	pre-miRNA binding
G	0071389	biological_process	cellular response to mineralocorticoid stimulus
G	0090543	cellular_component	Flemming body
G	1902570	biological_process	protein localization to nucleolus
H	0000054	biological_process	ribosomal subunit export from nucleus
H	0000055	biological_process	ribosomal large subunit export from nucleus
H	0000056	biological_process	ribosomal small subunit export from nucleus
H	0000070	biological_process	mitotic sister chromatid segregation
H	0000278	biological_process	mitotic cell cycle
H	0000287	molecular_function	magnesium ion binding
H	0000785	cellular_component	chromatin
H	0001673	cellular_component	male germ cell nucleus
H	0002177	cellular_component	manchette
H	0003682	molecular_function	chromatin binding
H	0003723	molecular_function	RNA binding
H	0003924	molecular_function	GTPase activity
H	0003925	molecular_function	G protein activity
H	0005049	molecular_function	nuclear export signal receptor activity
H	0005515	molecular_function	protein binding
H	0005525	molecular_function	GTP binding
H	0005634	cellular_component	nucleus
H	0005635	cellular_component	nuclear envelope
H	0005643	cellular_component	nuclear pore
H	0005654	cellular_component	nucleoplasm
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005814	cellular_component	centriole
H	0005829	cellular_component	cytosol
H	0006259	biological_process	DNA metabolic process
H	0006606	biological_process	protein import into nucleus
H	0006611	biological_process	protein export from nucleus
H	0006913	biological_process	nucleocytoplasmic transport
H	0007052	biological_process	mitotic spindle organization
H	0007286	biological_process	spermatid development
H	0008104	biological_process	protein localization
H	0014070	biological_process	response to organic cyclic compound
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
H	0016032	biological_process	viral process
H	0016787	molecular_function	hydrolase activity
H	0019003	molecular_function	GDP binding
H	0019904	molecular_function	protein domain specific binding
H	0021766	biological_process	hippocampus development
H	0030036	biological_process	actin cytoskeleton organization
H	0030496	cellular_component	midbody
H	0031503	biological_process	protein-containing complex localization
H	0032092	biological_process	positive regulation of protein binding
H	0032991	cellular_component	protein-containing complex
H	0035281	biological_process	pre-miRNA export from nucleus
H	0036126	cellular_component	sperm flagellum
H	0042307	biological_process	positive regulation of protein import into nucleus
H	0042470	cellular_component	melanosome
H	0042565	cellular_component	RNA nuclear export complex
H	0044877	molecular_function	protein-containing complex binding
H	0045296	molecular_function	cadherin binding
H	0045505	molecular_function	dynein intermediate chain binding
H	0046039	biological_process	GTP metabolic process
H	0046872	molecular_function	metal ion binding
H	0046982	molecular_function	protein heterodimerization activity
H	0051301	biological_process	cell division
H	0055037	cellular_component	recycling endosome
H	0061015	biological_process	snRNA import into nucleus
H	0061676	molecular_function	importin-alpha family protein binding
H	0070062	cellular_component	extracellular exosome
H	0070883	molecular_function	pre-miRNA binding
H	0071389	biological_process	cellular response to mineralocorticoid stimulus
H	0090543	cellular_component	Flemming body
H	1902570	biological_process	protein localization to nucleolus

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue GDP A 301

Chain	Residue
A	GLY20
A	ILE126
A	SER150
A	ALA151
A	LYS152
A	MG302
A	HOH404
A	HOH405
A	HOH416
A	THR21
A	GLY22
A	LYS23
A	THR24
A	THR25
A	ASN122
A	LYS123
A	ASP125

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 302

Chain	Residue
A	THR24
A	GDP301
A	HOH404
A	HOH409
A	HOH416
A	HOH418

---

site_id	AC3
Number of Residues	20
Details	binding site for residue GDP B 301

Chain	Residue
B	GLY20
B	THR21
B	GLY22
B	LYS23
B	THR24
B	THR25
B	ASN122
B	LYS123
B	ASP125
B	ILE126
B	SER150
B	ALA151
B	LYS152
B	MG302
B	HOH402
B	HOH408
B	HOH430
B	HOH452
B	HOH469
E	ASP190

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MG B 302

Chain	Residue
B	THR24
B	GDP301
B	HOH408
B	HOH430
B	HOH442
B	HOH452

---

site_id	AC5
Number of Residues	5
Details	binding site for residue MG B 303

Chain	Residue
B	GLU175
B	PO4304
B	HOH429
B	HOH471
E	HOH421

---

site_id	AC6
Number of Residues	10
Details	binding site for residue PO4 B 304

Chain	Residue
B	ARG166
B	GLU175
B	MG303
B	MG305
B	HOH424
B	HOH429
E	ARG166
E	GLU175
E	HOH403
E	HOH421

---

site_id	AC7
Number of Residues	6
Details	binding site for residue MG B 305

Chain	Residue
B	PO4304
B	HOH421
B	HOH424
E	GLU175
E	HOH403
E	HOH443

---

site_id	AC8
Number of Residues	19
Details	binding site for residue GDP C 301

Chain	Residue
C	GLY19
C	GLY20
C	THR21
C	GLY22
C	LYS23
C	THR24
C	THR25
C	ASN122
C	LYS123
C	ASP125
C	ILE126
C	SER150
C	ALA151
C	LYS152
C	MG302
C	HOH407
C	HOH412
C	HOH421
C	HOH440

---

site_id	AC9
Number of Residues	6
Details	binding site for residue MG C 302

Chain	Residue
C	THR24
C	GDP301
C	HOH407
C	HOH421
C	HOH440
E	HOH410

---

site_id	AD1
Number of Residues	6
Details	binding site for residue MG C 303

Chain	Residue
D	HOH409
D	HOH428
C	GLU175
C	PO4304
C	HOH406
C	HOH445

---

site_id	AD2
Number of Residues	11
Details	binding site for residue PO4 C 304

Chain	Residue
C	ARG166
C	GLU175
C	MG303
C	MG305
C	HOH406
C	HOH413
C	HOH419
D	ARG166
D	GLU175
D	HOH428
D	HOH433

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MG C 305

Chain	Residue
C	PO4304
C	HOH413
C	HOH419
D	GLU175
D	HOH433
D	HOH470

---

site_id	AD4
Number of Residues	19
Details	binding site for residue GDP D 301

Chain	Residue
C	ASP190
D	GLY20
D	THR21
D	GLY22
D	LYS23
D	THR24
D	THR25
D	ASN122
D	LYS123
D	ASP125
D	ILE126
D	SER150
D	ALA151
D	LYS152
D	MG302
D	HOH404
D	HOH413
D	HOH431
D	HOH441

---

site_id	AD5
Number of Residues	6
Details	binding site for residue MG D 302

Chain	Residue
D	THR24
D	GDP301
D	HOH413
D	HOH431
D	HOH432
D	HOH441

---

site_id	AD6
Number of Residues	19
Details	binding site for residue GDP E 301

Chain	Residue
B	LYS127
C	HOH420
E	GLY19
E	GLY20
E	THR21
E	GLY22
E	LYS23
E	THR24
E	THR25
E	ASN122
E	LYS123
E	ASP125
E	ILE126
E	SER150
E	ALA151
E	LYS152
E	MG302
E	HOH420
E	HOH438

---

site_id	AD7
Number of Residues	6
Details	binding site for residue MG E 302

Chain	Residue
C	HOH420
C	HOH429
E	THR24
E	GDP301
E	HOH420
E	HOH438

---

site_id	AD8
Number of Residues	19
Details	binding site for residue GDP F 301

Chain	Residue
F	GLY20
F	THR21
F	GLY22
F	LYS23
F	THR24
F	THR25
F	ASN122
F	LYS123
F	ASP125
F	ILE126
F	SER150
F	ALA151
F	LYS152
F	MG302
F	HOH409
F	HOH410
F	HOH416
F	HOH438
F	HOH443

---

site_id	AD9
Number of Residues	6
Details	binding site for residue MG F 302

Chain	Residue
F	THR24
F	GDP301
F	HOH409
F	HOH410
F	HOH416
F	HOH434

---

site_id	AE1
Number of Residues	18
Details	binding site for residue GDP G 301

Chain	Residue
G	GLY20
G	THR21
G	GLY22
G	LYS23
G	THR24
G	THR25
G	ASN122
G	LYS123
G	ASP125
G	ILE126
G	SER150
G	ALA151
G	LYS152
G	MG302
G	HOH401
G	HOH410
G	HOH417
G	HOH433

---

site_id	AE2
Number of Residues	6
Details	binding site for residue MG G 302

Chain	Residue
G	THR24
G	GDP301
G	HOH401
G	HOH410
G	HOH414
G	HOH417

---

site_id	AE3
Number of Residues	18
Details	binding site for residue GDP H 301

Chain	Residue
F	LYS127
H	GLY20
H	THR21
H	GLY22
H	LYS23
H	THR24
H	THR25
H	ASN122
H	LYS123
H	ASP125
H	ILE126
H	SER150
H	ALA151
H	LYS152
H	MG302
H	HOH405
H	HOH409
H	HOH422

---

site_id	AE4
Number of Residues	6
Details	binding site for residue MG H 302

Chain	Residue
H	THR24
H	GDP301
H	HOH409
H	HOH414
H	HOH417
H	HOH422

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:10078529, ECO:0000269|PubMed:10353245, ECO:0000269|PubMed:10367892, ECO:0000269|PubMed:11832950, ECO:0000269|PubMed:18611384, ECO:0000269|PubMed:19389996, ECO:0000269|PubMed:19505478, ECO:0000269|PubMed:24449914, ECO:0000269|PubMed:24915079, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:26349033, ECO:0000269|PubMed:28282025, ECO:0000269|PubMed:7885480, ECO:0007744|PDB:1IBR, ECO:0007744|PDB:1K5G, ECO:0007744|PDB:1RRP, ECO:0007744|PDB:3CH5, ECO:0007744|PDB:3GJ0, ECO:0007744|PDB:3GJ3, ECO:0007744|PDB:3GJ4, ECO:0007744|PDB:3GJ5, ECO:0007744|PDB:3GJ6, ECO:0007744|PDB:3GJ7, ECO:0007744|PDB:3GJ8, ECO:0007744|PDB:3GJX, ECO:0007744|PDB:3NBY, ECO:0007744|PDB:3NBZ, ECO:0007744|PDB:3NC0, ECO:0007744|PDB:3NC1, ECO:0007744|PDB:3ZJY, ECO:0007744|PDB:4C0Q, ECO:0007744|PDB:4OL0, ECO:0007744|PDB:5CIQ, ECO:0007744|PDB:5CIT, ECO:0007744|PDB:5CIW, ECO:0007744|PDB:5CLQ, ECO:0007744|PDB:5DH9, ECO:0007744|PDB:5DHA, ECO:0007744|PDB:5DHF, ECO:0007744|PDB:5DI9, ECO:0007744|PDB:5DIF, ECO:0007744|PDB:5DIS, ECO:0007744|PDB:5DLQ, ECO:0007744|PDB:5UWH, ECO:0007744|PDB:5UWI, ECO:0007744|PDB:5UWJ, ECO:0007744|PDB:5UWO, ECO:0007744|PDB:5UWP, ECO:0007744|PDB:5UWQ, ECO:0007744|PDB:5UWR, ECO:0007744|PDB:5UWS, ECO:0007744|PDB:5UWT, ECO:0007744|PDB:5UWU, ECO:0007744|PDB:5UWW

Chain	Residue	Details
A	ASP18
B	ASP18
C	ASP18
D	ASP18
E	ASP18
F	ASP18
G	ASP18
H	ASP18

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:10078529, ECO:0000269|PubMed:10353245, ECO:0000269|PubMed:10367892, ECO:0000269|PubMed:11832950, ECO:0000269|PubMed:19389996, ECO:0000269|PubMed:24449914, ECO:0000269|PubMed:24915079, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:26349033, ECO:0000269|PubMed:28282025, ECO:0000269|PubMed:7885480, ECO:0007744|PDB:1IBR, ECO:0007744|PDB:1K5D, ECO:0007744|PDB:1QBK, ECO:0007744|PDB:1RRP, ECO:0007744|PDB:3GJX, ECO:0007744|PDB:3NBY, ECO:0007744|PDB:3NBZ, ECO:0007744|PDB:3NC0, ECO:0007744|PDB:3NC1, ECO:0007744|PDB:3ZJY, ECO:0007744|PDB:4C0Q, ECO:0007744|PDB:4OL0, ECO:0007744|PDB:5CLL, ECO:0007744|PDB:5CLQ, ECO:0007744|PDB:5DH9, ECO:0007744|PDB:5DHA, ECO:0007744|PDB:5DHF, ECO:0007744|PDB:5DI9, ECO:0007744|PDB:5DIF, ECO:0007744|PDB:5DIS, ECO:0007744|PDB:5DLQ, ECO:0007744|PDB:5JLJ, ECO:0007744|PDB:5UWH, ECO:0007744|PDB:5UWI, ECO:0007744|PDB:5UWJ, ECO:0007744|PDB:5UWO, ECO:0007744|PDB:5UWP, ECO:0007744|PDB:5UWQ, ECO:0007744|PDB:5UWR, ECO:0007744|PDB:5UWS, ECO:0007744|PDB:5UWT, ECO:0007744|PDB:5UWU, ECO:0007744|PDB:5UWW

Chain	Residue	Details
A	GLU36
B	GLU36
C	GLU36
D	GLU36
E	GLU36
F	GLU36
G	GLU36
H	GLU36

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:10078529, ECO:0000269|PubMed:10353245, ECO:0000269|PubMed:10367892, ECO:0000269|PubMed:11832950, ECO:0000269|PubMed:18611384, ECO:0000269|PubMed:19389996, ECO:0000269|PubMed:19505478, ECO:0000269|PubMed:24449914, ECO:0000269|PubMed:24915079, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:26349033, ECO:0000269|PubMed:28282025, ECO:0000269|PubMed:7885480, ECO:0007744|PDB:1IBR, ECO:0007744|PDB:1K5D, ECO:0007744|PDB:1QBK, ECO:0007744|PDB:1RRP, ECO:0007744|PDB:3GJX, ECO:0007744|PDB:3NBY, ECO:0007744|PDB:3NBZ, ECO:0007744|PDB:3NC0, ECO:0007744|PDB:3NC1, ECO:0007744|PDB:3ZJY, ECO:0007744|PDB:4C0Q, ECO:0007744|PDB:4OL0, ECO:0007744|PDB:5DH9, ECO:0007744|PDB:5DHA, ECO:0007744|PDB:5DHF, ECO:0007744|PDB:5DI9, ECO:0007744|PDB:5DIF, ECO:0007744|PDB:5DIS, ECO:0007744|PDB:5DLQ, ECO:0007744|PDB:5JLJ, ECO:0007744|PDB:5UWH, ECO:0007744|PDB:5UWI, ECO:0007744|PDB:5UWJ, ECO:0007744|PDB:5UWO, ECO:0007744|PDB:5UWP, ECO:0007744|PDB:5UWQ, ECO:0007744|PDB:5UWR, ECO:0007744|PDB:5UWS, ECO:0007744|PDB:5UWT, ECO:0007744|PDB:5UWU, ECO:0007744|PDB:5UWW

Chain	Residue	Details
A	GLY68
B	GLY68
C	GLY68
D	GLY68
E	GLY68
F	GLY68
G	GLY68
H	GLY68

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:10078529, ECO:0000269|PubMed:10353245, ECO:0000269|PubMed:10367892, ECO:0000269|PubMed:11832950, ECO:0000269|PubMed:18611384, ECO:0000269|PubMed:19389996, ECO:0000269|PubMed:19505478, ECO:0000269|PubMed:24449914, ECO:0000269|PubMed:24915079, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:26349033, ECO:0000269|PubMed:28282025, ECO:0000269|PubMed:7885480, ECO:0007744|PDB:1IBR, ECO:0007744|PDB:1K5D, ECO:0007744|PDB:1QBK, ECO:0007744|PDB:1RRP, ECO:0007744|PDB:3CH5, ECO:0007744|PDB:3GJ0, ECO:0007744|PDB:3GJ3, ECO:0007744|PDB:3GJ4, ECO:0007744|PDB:3GJ5, ECO:0007744|PDB:3GJ6, ECO:0007744|PDB:3GJ7, ECO:0007744|PDB:3GJ8, ECO:0007744|PDB:3GJX, ECO:0007744|PDB:3NBY, ECO:0007744|PDB:3NBZ, ECO:0007744|PDB:3NC0, ECO:0007744|PDB:3NC1, ECO:0007744|PDB:3ZJY, ECO:0007744|PDB:4C0Q, ECO:0007744|PDB:4OL0, ECO:0007744|PDB:5CIQ, ECO:0007744|PDB:5CIT, ECO:0007744|PDB:5CIW, ECO:0007744|PDB:5CJ2, ECO:0007744|PDB:5CLL, ECO:0007744|PDB:5DH9, ECO:0007744|PDB:5DHA, ECO:0007744|PDB:5DHF, ECO:0007744|PDB:5DI9, ECO:0007744|PDB:5DIF, ECO:0007744|PDB:5DIS, ECO:0007744|PDB:5DLQ, ECO:0007744|PDB:5JLJ, ECO:0007744|PDB:5UWH, ECO:0007744|PDB:5UWI, ECO:0007744|PDB:5UWJ, ECO:0007744|PDB:5UWO, ECO:0007744|PDB:5UWP, ECO:0007744|PDB:5UWQ, ECO:0007744|PDB:5UWR, ECO:0007744|PDB:5UWS, ECO:0007744|PDB:5UWT, ECO:0007744|PDB:5UWU, ECO:0007744|PDB:5UWW

Chain	Residue	Details
A	ASN122
B	ASN122
C	ASN122
D	ASN122
E	ASN122
F	ASN122
G	ASN122
H	ASN122

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:10078529, ECO:0000269|PubMed:10353245, ECO:0000269|PubMed:10367892, ECO:0000269|PubMed:11832950, ECO:0000269|PubMed:18611384, ECO:0000269|PubMed:19389996, ECO:0000269|PubMed:19505478, ECO:0000269|PubMed:24449914, ECO:0000269|PubMed:24915079, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:26349033, ECO:0000269|PubMed:28282025, ECO:0000269|PubMed:7885480, ECO:0007744|PDB:1K5G, ECO:0007744|PDB:3CH5, ECO:0007744|PDB:3GJ0, ECO:0007744|PDB:3GJ3, ECO:0007744|PDB:3GJ4, ECO:0007744|PDB:3GJ5, ECO:0007744|PDB:3GJ6, ECO:0007744|PDB:3GJ7, ECO:0007744|PDB:3GJ8, ECO:0007744|PDB:3GJX, ECO:0007744|PDB:3NBY, ECO:0007744|PDB:3NBZ, ECO:0007744|PDB:3NC0, ECO:0007744|PDB:3NC1, ECO:0007744|PDB:3ZJY, ECO:0007744|PDB:4C0Q, ECO:0007744|PDB:4OL0, ECO:0007744|PDB:5CIQ, ECO:0007744|PDB:5CIT, ECO:0007744|PDB:5CIW, ECO:0007744|PDB:5CJ2, ECO:0007744|PDB:5CLL, ECO:0007744|PDB:5CLQ, ECO:0007744|PDB:5DH9, ECO:0007744|PDB:5DHA, ECO:0007744|PDB:5DHF, ECO:0007744|PDB:5DI9, ECO:0007744|PDB:5DIF, ECO:0007744|PDB:5DIS, ECO:0007744|PDB:5DLQ, ECO:0007744|PDB:5JLJ, ECO:0007744|PDB:5UWH, ECO:0007744|PDB:5UWI, ECO:0007744|PDB:5UWJ, ECO:0007744|PDB:5UWO, ECO:0007744|PDB:5UWP, ECO:0007744|PDB:5UWQ, ECO:0007744|PDB:5UWR, ECO:0007744|PDB:5UWS, ECO:0007744|PDB:5UWT, ECO:0007744|PDB:5UWU, ECO:0007744|PDB:5UWW

Chain	Residue	Details
A	SER150
B	SER150
C	SER150
D	SER150
E	SER150
F	SER150
G	SER150
H	SER150

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	SITE: Essential for GTP hydrolysis => ECO:0000269|PubMed:18591255, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:8636225

Chain	Residue	Details
A	GLN69
B	GLN69
C	GLN69
D	GLN69
E	GLN69
F	GLN69
G	GLN69
H	GLN69

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.12, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2
E	ALA2
F	ALA2
G	ALA2
H	ALA2

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR24
B	THR24
C	THR24
D	THR24
E	THR24
F	THR24
G	THR24
H	THR24

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:31075303

Chain	Residue	Details
A	LYS37
B	LYS37
C	LYS37
D	LYS37
E	LYS37
F	LYS37
G	LYS37
H	LYS37

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS60
E	LYS99
F	LYS60
F	LYS99
G	LYS60
G	LYS99
H	LYS60
H	LYS99
A	LYS99
B	LYS60
B	LYS99
C	LYS60
C	LYS99
D	LYS60
D	LYS99
E	LYS60

---

site_id	SWS_FT_FI11
Number of Residues	8
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS71
B	LYS71
C	LYS71
D	LYS71
E	LYS71
F	LYS71
G	LYS71
H	LYS71

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:29040603

Chain	Residue	Details
A	LYS134
B	LYS134
C	LYS134
D	LYS134
E	LYS134
F	LYS134
G	LYS134
H	LYS134

---

site_id	SWS_FT_FI13
Number of Residues	8
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62827

Chain	Residue	Details
A	LYS159
B	LYS159
C	LYS159
D	LYS159
E	LYS159
F	LYS159
G	LYS159
H	LYS159

---

site_id	SWS_FT_FI14
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate

Chain	Residue	Details
A	LYS71
B	LYS71
C	LYS71
D	LYS71
E	LYS71
F	LYS71
G	LYS71
H	LYS71

---

site_id	SWS_FT_FI15
Number of Residues	16
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
E	LYS152
F	LYS152
G	LYS152
H	LYS152
A	LYS152
B	LYS152
C	LYS152
D	LYS152

---