Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0010506 | biological_process | regulation of autophagy |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 51W A 401 |
| Chain | Residue |
| A | ILE22 |
| A | GLN142 |
| A | LEU145 |
| A | HOH522 |
| A | ALA44 |
| A | MET92 |
| A | GLU93 |
| A | TYR94 |
| A | CYS95 |
| A | GLY98 |
| A | ASP99 |
| A | HIS105 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | GLU73 |
| A | GLU93 |
| A | PRO149 |
| A | ARG160 |
| A | LYS162 |
| A | ALA249 |
| A | GLN253 |
| A | GOL403 |
| A | HOH512 |
| A | HOH530 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | LEU41 |
| A | GLU93 |
| A | TYR94 |
| A | ALA249 |
| A | GOL402 |
| A | HOH508 |
| A | HOH511 |
| A | HOH513 |
| A | HOH569 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | GLY23 |
| A | ASP165 |
| A | HOH523 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGHGAFAVVFkGrhraahdle.........VAVK |
| Chain | Residue | Details |
| A | ILE22-LYS46 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpqNILL |
| Chain | Residue | Details |
| A | ILE134-LEU146 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20921139","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O70405","evidenceCode":"ECO:0000250"}]} |
