5CHG
Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0034061 | molecular_function | DNA polymerase activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0034061 | molecular_function | DNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | SER339 |
| A | ILE341 |
| A | ALA344 |
| P | DT4 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 601 |
| Chain | Residue |
| B | ARG514 |
| B | ARG517 |
| B | DGT603 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | DGT603 |
| B | ASP427 |
| B | ASP429 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue DGT B 603 |
| Chain | Residue |
| B | ARG386 |
| B | GLY416 |
| B | SER417 |
| B | ARG420 |
| B | GLY426 |
| B | ASP427 |
| B | ASP429 |
| B | TYR505 |
| B | PHE506 |
| B | GLY508 |
| B | ASN513 |
| B | SO4601 |
| B | MG602 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 84 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"14992725","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Region: {"description":"Involved in primer binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17475573","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PFQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17475573","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PFO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PFQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
