Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 1001 |
| Chain | Residue |
| B | ASP508 |
| B | ASP510 |
| B | HOH1102 |
| B | HOH1108 |
| B | HOH1114 |
| B | HOH1127 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 1002 |
| Chain | Residue |
| N | DG2013 |
| B | ASN475 |
| B | ASN476 |
| B | GLU477 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ASN313 |
| A | SER315 |
| A | VAL316 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 502 |
| Chain | Residue |
| A | TYR322 |
| A | THR325 |
| A | GLN328 |
| A | HOH684 |
| A | HOH689 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG47 |
| A | ARG48 |
| A | GLU156 |
| A | PRO157 |
| A | HOH632 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 701 |
| Chain | Residue |
| D | ASP508 |
| D | ASP510 |
| D | HOH804 |
| D | HOH808 |
| D | HOH811 |
| D | HOH816 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue 54Q I 2101 |
| Chain | Residue |
| A | PTR123 |
| A | HOH606 |
| D | GLY436 |
| D | ASP437 |
| D | ARG458 |
| D | GLY459 |
| D | HOH802 |
| F | DC8 |
| I | DC2012 |
| I | DG2013 |
| N | DG2009 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue DT N 2101 |
| Chain | Residue |
| A | SER240 |
| A | SER330 |
| C | ARG414 |
| N | DT2019 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue 54Q N 2102 |
| Chain | Residue |
| B | GLY436 |
| B | ASP437 |
| B | ARG458 |
| B | GLY459 |
| B | HOH1101 |
| C | PTR123 |
| E | DC8 |
| I | DG2009 |
| N | DC2012 |
| N | DG2013 |
| N | HOH2214 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PTR123 | |
| C | PTR123 | |
| B | ASP510 | |
| D | GLU435 | |
| D | ASP508 | |
| D | ASP510 | |
| Chain | Residue | Details |
| B | LYS460 | |
| B | ASN463 | |
| D | LYS460 | |
| D | ASN463 | |
