Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | GLU222 |
| A | PRO223 |
| A | GLU267 |
| A | PRO268 |
| A | VAL270 |
| A | TRP272 |
| A | ASN273 |
| A | PRO298 |
| A | HIS299 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | ARG90 |
| A | PHE432 |
| A | VAL433 |
| A | SER434 |
| A | ASP435 |
| A | ARG458 |
| A | HOH718 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | ILE41 |
| A | THR42 |
| A | ASP53 |
| A | ARG57 |
| A | HIS133 |
| A | HOH703 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | THR39 |
| A | PRO40 |
| A | ILE41 |
| A | ALA129 |
| A | GLY131 |
| A | EDO606 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | TRP272 |
| A | PRO277 |
| A | SER278 |
| A | ASN331 |
| A | ALA334 |
| A | ARG338 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | THR128 |
| A | ALA129 |
| A | PRO212 |
| A | EDO604 |
| A | HOH706 |
| A | HOH806 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | ALA443 |
| A | VAL444 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | ASP68 |
| A | TYR73 |
| A | LEU74 |
| A | GLY99 |
| A | THR100 |
| A | SER101 |
| A | TYR116 |
| A | HOH702 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | PHE170 |
| A | GLU222 |
| A | ASN273 |
| A | GLN274 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | ARG228 |
| A | SER231 |
| A | CYS237 |
| A | PRO238 |
| A | ASP239 |
| A | PHE240 |
| A | HOH743 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | GLU114 |
| A | ALA203 |
| A | ARG207 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 612 |
| Chain | Residue |
| A | ASP68 |
| A | ASP70 |
| A | PRO72 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | GLN108 |
| B | ARG109 |
| B | ARG228 |
| B | PHE240 |
| B | THR243 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | ASP103 |
| B | SER144 |
| B | LYS145 |
| B | ASN150 |
| B | GLY151 |
| B | PHE152 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | ALA339 |
| B | ASN340 |
| B | HOH703 |
| B | HOH809 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | HIS50 |
| B | LEU51 |
| B | THR58 |
| B | VAL59 |
| B | PHE367 |
| B | HOH717 |
| B | HOH732 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | PRO168 |
| B | GLY169 |
| B | PHE170 |
| B | PRO171 |
| B | LEU172 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | ASP326 |
| B | ARG362 |
| B | ARG366 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| B | THR271 |
| B | TRP272 |
| B | MET276 |
| B | PRO277 |
| B | SER278 |
| B | HOH707 |
| B | HOH748 |
| B | PRO268 |
| B | ASN269 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| B | GLN245 |
| B | GLN249 |
| B | ALA288 |
| B | LEU289 |
| B | THR290 |
| B | THR291 |
| B | HOH715 |
| site_id | AE3 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide ASP B 118 and ARG B 207 |
| Chain | Residue |
| B | GLU114 |
| B | ALA115 |
| B | TYR116 |
| B | LEU117 |
| B | ARG119 |
| B | LEU120 |
| B | THR121 |
| B | GLY122 |
| B | ALA203 |
| B | LEU204 |
| B | ALA205 |
| B | GLU206 |
| B | VAL208 |
| B | GLU209 |
| B | HOH710 |
