5cbx

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005815	cellular_component	microtubule organizing center
A	0005759	cellular_component	mitochondrial matrix
A	0016607	cellular_component	nuclear speck
A	0005654	cellular_component	nucleoplasm
A	0005634	cellular_component	nucleus
A	0032991	cellular_component	protein-containing complex
A	0005819	cellular_component	spindle
A	0001047	molecular_function	core promoter binding
A	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0004883	molecular_function	glucocorticoid receptor activity
A	0051879	molecular_function	Hsp90 protein binding
A	0004879	molecular_function	nuclear receptor activity
A	0019901	molecular_function	protein kinase binding
A	0003723	molecular_function	RNA binding
A	0000978	molecular_function	RNA polymerase II proximal promoter sequence-specific DNA binding
A	0005496	molecular_function	steroid binding
A	1990239	molecular_function	steroid hormone binding
A	0032183	molecular_function	SUMO binding
A	0008270	molecular_function	zinc ion binding
A	0006915	biological_process	apoptotic process
A	0007049	biological_process	cell cycle
A	0051301	biological_process	cell division
A	0071549	biological_process	cellular response to dexamethasone stimulus
A	0071385	biological_process	cellular response to glucocorticoid stimulus
A	0071383	biological_process	cellular response to steroid hormone stimulus
A	0071560	biological_process	cellular response to transforming growth factor beta stimulus
A	0006325	biological_process	chromatin organization
A	0007059	biological_process	chromosome segregation
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0007165	biological_process	signal transduction
A	0006366	biological_process	transcription by RNA polymerase II
A	0006367	biological_process	transcription initiation from RNA polymerase II promoter
A	0006351	biological_process	transcription, DNA-templated
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005815	cellular_component	microtubule organizing center
B	0005759	cellular_component	mitochondrial matrix
B	0016607	cellular_component	nuclear speck
B	0005654	cellular_component	nucleoplasm
B	0005634	cellular_component	nucleus
B	0032991	cellular_component	protein-containing complex
B	0005819	cellular_component	spindle
B	0001047	molecular_function	core promoter binding
B	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0004883	molecular_function	glucocorticoid receptor activity
B	0051879	molecular_function	Hsp90 protein binding
B	0004879	molecular_function	nuclear receptor activity
B	0019901	molecular_function	protein kinase binding
B	0003723	molecular_function	RNA binding
B	0000978	molecular_function	RNA polymerase II proximal promoter sequence-specific DNA binding
B	0005496	molecular_function	steroid binding
B	1990239	molecular_function	steroid hormone binding
B	0032183	molecular_function	SUMO binding
B	0008270	molecular_function	zinc ion binding
B	0006915	biological_process	apoptotic process
B	0007049	biological_process	cell cycle
B	0051301	biological_process	cell division
B	0071549	biological_process	cellular response to dexamethasone stimulus
B	0071385	biological_process	cellular response to glucocorticoid stimulus
B	0071383	biological_process	cellular response to steroid hormone stimulus
B	0071560	biological_process	cellular response to transforming growth factor beta stimulus
B	0006325	biological_process	chromatin organization
B	0007059	biological_process	chromosome segregation
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0006355	biological_process	regulation of transcription, DNA-templated
B	0007165	biological_process	signal transduction
B	0006366	biological_process	transcription by RNA polymerase II
B	0006367	biological_process	transcription initiation from RNA polymerase II promoter
B	0006351	biological_process	transcription, DNA-templated
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005815	cellular_component	microtubule organizing center
E	0005759	cellular_component	mitochondrial matrix
E	0016607	cellular_component	nuclear speck
E	0005654	cellular_component	nucleoplasm
E	0005634	cellular_component	nucleus
E	0032991	cellular_component	protein-containing complex
E	0005819	cellular_component	spindle
E	0001047	molecular_function	core promoter binding
E	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
E	0004883	molecular_function	glucocorticoid receptor activity
E	0051879	molecular_function	Hsp90 protein binding
E	0004879	molecular_function	nuclear receptor activity
E	0019901	molecular_function	protein kinase binding
E	0003723	molecular_function	RNA binding
E	0000978	molecular_function	RNA polymerase II proximal promoter sequence-specific DNA binding
E	0005496	molecular_function	steroid binding
E	1990239	molecular_function	steroid hormone binding
E	0032183	molecular_function	SUMO binding
E	0008270	molecular_function	zinc ion binding
E	0006915	biological_process	apoptotic process
E	0007049	biological_process	cell cycle
E	0051301	biological_process	cell division
E	0071549	biological_process	cellular response to dexamethasone stimulus
E	0071385	biological_process	cellular response to glucocorticoid stimulus
E	0071383	biological_process	cellular response to steroid hormone stimulus
E	0071560	biological_process	cellular response to transforming growth factor beta stimulus
E	0006325	biological_process	chromatin organization
E	0007059	biological_process	chromosome segregation
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0006355	biological_process	regulation of transcription, DNA-templated
E	0007165	biological_process	signal transduction
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation from RNA polymerase II promoter
E	0006351	biological_process	transcription, DNA-templated
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005815	cellular_component	microtubule organizing center
F	0005759	cellular_component	mitochondrial matrix
F	0016607	cellular_component	nuclear speck
F	0005654	cellular_component	nucleoplasm
F	0005634	cellular_component	nucleus
F	0032991	cellular_component	protein-containing complex
F	0005819	cellular_component	spindle
F	0001047	molecular_function	core promoter binding
F	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
F	0004883	molecular_function	glucocorticoid receptor activity
F	0051879	molecular_function	Hsp90 protein binding
F	0004879	molecular_function	nuclear receptor activity
F	0019901	molecular_function	protein kinase binding
F	0003723	molecular_function	RNA binding
F	0000978	molecular_function	RNA polymerase II proximal promoter sequence-specific DNA binding
F	0005496	molecular_function	steroid binding
F	1990239	molecular_function	steroid hormone binding
F	0032183	molecular_function	SUMO binding
F	0008270	molecular_function	zinc ion binding
F	0006915	biological_process	apoptotic process
F	0007049	biological_process	cell cycle
F	0051301	biological_process	cell division
F	0071549	biological_process	cellular response to dexamethasone stimulus
F	0071385	biological_process	cellular response to glucocorticoid stimulus
F	0071383	biological_process	cellular response to steroid hormone stimulus
F	0071560	biological_process	cellular response to transforming growth factor beta stimulus
F	0006325	biological_process	chromatin organization
F	0007059	biological_process	chromosome segregation
F	0000122	biological_process	negative regulation of transcription by RNA polymerase II
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0006355	biological_process	regulation of transcription, DNA-templated
F	0007165	biological_process	signal transduction
F	0006366	biological_process	transcription by RNA polymerase II
F	0006367	biological_process	transcription initiation from RNA polymerase II promoter
F	0006351	biological_process	transcription, DNA-templated

Functional Information from PDB Data

site_id

Number of Residues

Details

AC1

binding site for residue ZN A 501

Chain	Residue
A	CYS421
A	CYS424
A	CYS438
A	CYS441

AC2

binding site for residue ZN A 502

Chain	Residue
A	CYS457
A	CYS463
A	CYS473
A	CYS476

AC3

binding site for residue ZN B 501

Chain	Residue
B	CYS421
B	CYS424
B	CYS438
B	CYS441

AC4

binding site for residue ZN B 502

Chain	Residue
B	CYS457
B	CYS463
B	CYS473
B	CYS476

AC5

binding site for residue ZN E 501

Chain	Residue
E	CYS421
E	CYS424
E	CYS438
E	CYS441

AC6

binding site for residue ZN E 502

Chain	Residue
E	CYS457
E	CYS463
E	CYS473
E	CYS476

AC7

binding site for residue ZN F 501

Chain	Residue
F	CYS421
F	CYS424
F	CYS438
F	CYS441

AC8

binding site for residue ZN F 502

Chain	Residue
F	CYS457
F	CYS463
F	CYS473
F	CYS476

Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_id

Number of Residues

Details

Functional Information from PROSITE/UniProt

site_id

Number of Residues

Details

Functional Information from SwissProt/UniProt

site_id

Number of Residues

Details

Catalytic Information from CSA

site_id

Number of Residues

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)

AncGR DNA Binding Domain - (+)GRE Complex

Functional Information from GO Data

Functional Information from PDB Data

Functional Information from PDB atom coordinates for the "HETATM" binding sites

Functional Information from PROSITE/UniProt

Functional Information from SwissProt/UniProt

Catalytic Information from CSA