5CBE

E10 in complex with CXCL13

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0003823	molecular_function	antigen binding
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0016064	biological_process	immunoglobulin mediated immune response
A	0019814	cellular_component	immunoglobulin complex
A	0072562	cellular_component	blood microparticle
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0003823	molecular_function	antigen binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
B	0019814	cellular_component	immunoglobulin complex
B	0070062	cellular_component	extracellular exosome
C	0002250	biological_process	adaptive immune response
C	0002376	biological_process	immune system process
C	0003823	molecular_function	antigen binding
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
C	0016020	cellular_component	membrane
C	0016064	biological_process	immunoglobulin mediated immune response
C	0019814	cellular_component	immunoglobulin complex
C	0072562	cellular_component	blood microparticle
D	0002250	biological_process	adaptive immune response
D	0002376	biological_process	immune system process
D	0003823	molecular_function	antigen binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005886	cellular_component	plasma membrane
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane
D	0019814	cellular_component	immunoglobulin complex
D	0070062	cellular_component	extracellular exosome
E	0002467	biological_process	germinal center formation
E	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
E	0002544	biological_process	chronic inflammatory response
E	0002920	biological_process	regulation of humoral immune response
E	0005125	molecular_function	cytokine activity
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0006935	biological_process	chemotaxis
E	0006952	biological_process	defense response
E	0006954	biological_process	inflammatory response
E	0006955	biological_process	immune response
E	0007166	biological_process	cell surface receptor signaling pathway
E	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
E	0007267	biological_process	cell-cell signaling
E	0008009	molecular_function	chemokine activity
E	0008201	molecular_function	heparin binding
E	0010820	biological_process	positive regulation of T cell chemotaxis
E	0017134	molecular_function	fibroblast growth factor binding
E	0030593	biological_process	neutrophil chemotaxis
E	0031724	molecular_function	CXCR5 chemokine receptor binding
E	0031735	molecular_function	CCR10 chemokine receptor binding
E	0033625	biological_process	positive regulation of integrin activation
E	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
E	0035754	biological_process	B cell chemotaxis
E	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
E	0042742	biological_process	defense response to bacterium
E	0045236	molecular_function	CXCR chemokine receptor binding
E	0045765	biological_process	regulation of angiogenesis
E	0048018	molecular_function	receptor ligand activity
E	0048248	molecular_function	CXCR3 chemokine receptor binding
E	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0070098	biological_process	chemokine-mediated signaling pathway
E	0071222	biological_process	cellular response to lipopolysaccharide
E	0090630	biological_process	activation of GTPase activity
E	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
F	0002467	biological_process	germinal center formation
F	0002518	biological_process	lymphocyte chemotaxis across high endothelial venule
F	0002544	biological_process	chronic inflammatory response
F	0002920	biological_process	regulation of humoral immune response
F	0005125	molecular_function	cytokine activity
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0006935	biological_process	chemotaxis
F	0006952	biological_process	defense response
F	0006954	biological_process	inflammatory response
F	0006955	biological_process	immune response
F	0007166	biological_process	cell surface receptor signaling pathway
F	0007204	biological_process	positive regulation of cytosolic calcium ion concentration
F	0007267	biological_process	cell-cell signaling
F	0008009	molecular_function	chemokine activity
F	0008201	molecular_function	heparin binding
F	0010820	biological_process	positive regulation of T cell chemotaxis
F	0017134	molecular_function	fibroblast growth factor binding
F	0030593	biological_process	neutrophil chemotaxis
F	0031724	molecular_function	CXCR5 chemokine receptor binding
F	0031735	molecular_function	CCR10 chemokine receptor binding
F	0033625	biological_process	positive regulation of integrin activation
F	0033634	biological_process	positive regulation of cell-cell adhesion mediated by integrin
F	0035754	biological_process	B cell chemotaxis
F	0035768	biological_process	endothelial cell chemotaxis to fibroblast growth factor
F	0042742	biological_process	defense response to bacterium
F	0045236	molecular_function	CXCR chemokine receptor binding
F	0045765	biological_process	regulation of angiogenesis
F	0048018	molecular_function	receptor ligand activity
F	0048248	molecular_function	CXCR3 chemokine receptor binding
F	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
F	0070098	biological_process	chemokine-mediated signaling pathway
F	0071222	biological_process	cellular response to lipopolysaccharide
F	0090630	biological_process	activation of GTPase activity
F	2000545	biological_process	negative regulation of endothelial cell chemotaxis to fibroblast growth factor

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO A 201

Chain	Residue
A	ASP100
A	ALA100
B	TRP32
B	ASP50

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Functional Information from PROSITE/UniProt

site_id	PS00471
Number of Residues	46
Details	SMALL_CYTOKINES_CXC Small cytokines (intercrine/chemokine) C-x-C subfamily signature. CrCVqessvfIprRfIdrIqilprGngCprkEIIvwkknksiv.CVD

Chain	Residue	Details
E	CYS9-ASP54

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:500108

Chain	Residue	Details
B	ILE21
D	ILE21

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