Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue B12 A 300 |
| Chain | Residue |
| A | LEU121 |
| A | SER145 |
| A | GLY174 |
| A | GLU175 |
| A | ARG176 |
| A | HIS177 |
| A | GLU178 |
| A | ILE179 |
| A | GLY180 |
| A | SER222 |
| A | VAL224 |
| A | LEU124 |
| A | LEU225 |
| A | GLY247 |
| A | GLY248 |
| A | GLN249 |
| A | MET264 |
| A | ASP266 |
| A | LEU267 |
| A | 5AD301 |
| A | HOH401 |
| A | HOH403 |
| A | ARG125 |
| A | HOH406 |
| A | HOH408 |
| A | HOH437 |
| A | HOH442 |
| A | GLY128 |
| A | GLU129 |
| A | TRP131 |
| A | HIS132 |
| A | GLU141 |
| A | HIS142 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 5AD A 301 |
| Chain | Residue |
| A | TRP131 |
| A | VAL138 |
| A | GLU141 |
| A | HIS142 |
| A | B12300 |
| B | ASP201 |
| B | HOH424 |
| site_id | AC3 |
| Number of Residues | 34 |
| Details | binding site for residue B12 B 301 |
| Chain | Residue |
| B | LEU121 |
| B | LEU124 |
| B | ARG125 |
| B | GLY128 |
| B | TRP131 |
| B | HIS132 |
| B | GLU141 |
| B | HIS142 |
| B | SER145 |
| B | ARG149 |
| B | GLY174 |
| B | GLU175 |
| B | ARG176 |
| B | HIS177 |
| B | GLU178 |
| B | ILE179 |
| B | GLY180 |
| B | VAL220 |
| B | LEU221 |
| B | SER222 |
| B | VAL224 |
| B | LEU225 |
| B | GLY247 |
| B | GLY248 |
| B | GLN249 |
| B | MET264 |
| B | LEU267 |
| B | 5AD302 |
| B | HOH401 |
| B | HOH402 |
| B | HOH415 |
| B | HOH418 |
| B | HOH434 |
| D | ARG230 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue 5AD B 302 |
| Chain | Residue |
| A | ASP201 |
| A | PRO203 |
| B | TRP131 |
| B | VAL138 |
| B | GLU141 |
| B | HIS142 |
| B | B12301 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | LYS238 |
| B | ALA241 |
| B | PRO242 |
| B | ARG243 |
| B | VAL244 |
| B | GLY260 |
| B | GLU262 |
| site_id | AC6 |
| Number of Residues | 34 |
| Details | binding site for residue B12 C 300 |
| Chain | Residue |
| C | ARG176 |
| C | HIS177 |
| C | GLU178 |
| C | ILE179 |
| C | GLY180 |
| C | VAL220 |
| C | LEU221 |
| C | SER222 |
| C | VAL224 |
| C | LEU225 |
| C | GLY247 |
| C | GLY248 |
| C | GLN249 |
| C | MET264 |
| C | ASP266 |
| C | LEU267 |
| C | 5AD301 |
| C | HOH408 |
| C | HOH409 |
| C | HOH414 |
| C | HOH433 |
| C | HOH447 |
| C | HOH452 |
| C | LEU121 |
| C | LEU124 |
| C | ARG125 |
| C | GLY128 |
| C | GLU129 |
| C | TRP131 |
| C | GLU141 |
| C | HIS142 |
| C | SER145 |
| C | GLY174 |
| C | GLU175 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue 5AD C 301 |
| Chain | Residue |
| C | TRP131 |
| C | VAL138 |
| C | GLU141 |
| C | HIS142 |
| C | B12300 |
| C | HOH404 |
| C | HOH442 |
| C | HOH445 |
| D | ASP201 |
| site_id | AC8 |
| Number of Residues | 37 |
| Details | binding site for residue B12 D 300 |
| Chain | Residue |
| B | ALA231 |
| B | HOH416 |
| B | HOH431 |
| D | LEU121 |
| D | LEU124 |
| D | ARG125 |
| D | GLY128 |
| D | TRP131 |
| D | HIS132 |
| D | GLU141 |
| D | HIS142 |
| D | SER145 |
| D | ARG149 |
| D | GLY174 |
| D | GLU175 |
| D | ARG176 |
| D | HIS177 |
| D | GLU178 |
| D | ILE179 |
| D | GLY180 |
| D | LEU221 |
| D | SER222 |
| D | VAL224 |
| D | LEU225 |
| D | GLY247 |
| D | GLY248 |
| D | GLN249 |
| D | MET264 |
| D | ASP266 |
| D | LEU267 |
| D | 5AD301 |
| D | HOH402 |
| D | HOH407 |
| D | HOH413 |
| D | HOH427 |
| D | HOH429 |
| D | HOH447 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue 5AD D 301 |
| Chain | Residue |
| C | ASP201 |
| C | PRO203 |
| D | TRP131 |
| D | VAL138 |
| D | GLU141 |
| D | HIS142 |
| D | B12300 |
| D | HOH401 |
| D | HOH452 |
