5C69
Crystal Structure of Prefusion-stabilized RSV F variant PR-DM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 601 |
| Chain | Residue |
| A | PHE110 |
| A | ARG312 |
| A | GLN327 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | HOH784 |
| A | SER416 |
| A | LYS418 |
| A | LYS438 |
| A | SER439 |
| A | HOH747 |
| A | HOH750 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | ASN250 |
| A | ARG337 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | LEU166 |
| A | ASP167 |
| A | LYS199 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | VAL212 |
| A | ASN213 |
| A | HOH701 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | ASN417 |
| A | LYS418 |
| A | GLY419 |
| A | LYS434 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | PRO238 |
| A | ASN399 |
| A | ASN401 |
| A | ARG402 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NHE A 608 |
| Chain | Residue |
| A | PHE110 |
| A | GLY112 |
| A | PHE113 |
| A | PHE113 |
| A | GLN327 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue NHE A 609 |
| Chain | Residue |
| A | PHE360 |
| A | PHE450 |
| A | TYR451 |
| A | ASP452 |
| A | VAL455 |
| A | ASN469 |
| A | HOH702 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 610 |
| Chain | Residue |
| A | ASN189 |
| A | ASN189 |
| A | ILE190 |
| A | ILE190 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 611 |
| Chain | Residue |
| A | TRP52 |
| A | TYR431 |
| A | HOH776 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 612 |
| Chain | Residue |
| A | LYS288 |
| A | TRP314 |
| A | ALA328 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 613 |
| Chain | Residue |
| A | LYS129 |
| A | GLN435 |
| A | GLU436 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Region: {"description":"Fusion peptide","evidences":[{"source":"UniProtKB","id":"P11209","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Coiled coil: {"evidences":[{"source":"PubMed","id":"10846072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29212939","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 51 |
| Details | Coiled coil: {"evidences":[{"source":"PubMed","id":"19966279","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31268705","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10846072","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"PubMed","id":"21586636","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"PubMed","id":"21586636","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28469033","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"PubMed","id":"21586636","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24179220","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
