5C1S
Crystal structure of the GDP-bound fast hydrolyzing mutant (V71A/K73Q) of EhRabX3 from Entamoeba histolytica
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005768 | cellular_component | endosome |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0043227 | cellular_component | membrane-bounded organelle |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005768 | cellular_component | endosome |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0043227 | cellular_component | membrane-bounded organelle |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GDP A 401 |
| Chain | Residue |
| A | SER29 |
| A | GLY30 |
| A | VAL31 |
| A | GLY32 |
| A | THR34 |
| A | THR35 |
| A | ASP130 |
| A | THR158 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue GDP B 401 |
| Chain | Residue |
| B | SER29 |
| B | GLY30 |
| B | VAL31 |
| B | GLY32 |
| B | LYS33 |
| B | THR34 |
| B | THR35 |
| B | ASP130 |
| B | THR158 |
| B | HOH503 |
| A | GLN73 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide ARG B 198 and TRP B 310 |
| Chain | Residue |
| B | THR194 |
| B | THR195 |
| B | ILE197 |
| B | ALA283 |
| B | ASP309 |
| B | LEU311 |
| B | SER319 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide GLY B 207 and ASP B 209 |
| Chain | Residue |
| B | THR206 |
| B | HIS208 |
| B | PHE210 |
| B | MSE211 |
